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87 Cards in this Set

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is cholecystectomy recommended in asx pts who have been found with gallstones?
NO, exception in IC host, porcelain gb, and stones >3cm
three m/c dx in RUQ px?
acute cholecystitis--> should have fever
cholelithiasis
biliary colic

others = GE, PUD, hepatitis, renal colic, pneum, pyelonephritis
is DM associated with gallstones?
no
radiation of pain to scapula seen with murphy's sign?
gallstone disease (clith, citis, or bcolic)
what is murphy's sign?
inspiratory arrest during dep palpation of RUQ due to pain
elevated bilirubin in cholelithiasis is due to what?
not due to cbd obstruction but due to inflammation and cholestasis
clithiasis has what on CBC? b/c?
MILD leukocytosis
hyperbilirubinemia
alp, elevated mildy
tx for symptomatic cholelithiasis?
cholecystectomy
what type of surgery is cholecystectomy? what kinds of AB's required?
clean-contaminated = need only inital dose of 1st gen ceph
UNLESS due to cholecystitis = give 2nd gen cehp tocover e.coli (or other common ones = enterobacter, klebsiella, enterococcus, g-a naerobes)
m/c complication of cholecystectomy?
injury to CBD --> strictures, infection, or cirrhosis!! or
injury to hepatic artery --> hep ischemic injury or bile duct ischemia and stricture
m/c cholecystitis bugs?
ECOLI!!!
then enterobacter, klebsiella, enterococcus, g-a naerobes
evidence of CBD obstruction?
CBD or other bile duct dilations
tx for bile duct obstruction?
lap cholecystectomy + intraop cholangiogram
or ERCP (pre or post surg)
sx cholelithiasis or gallstone pcreatitis in pregnant patient...NSIM?
NO surgery; just give hydration and px management and wait until after preg to remove gb
but if cholecystitis, obstr jaundice, or peritonitis, do surgery.
biliary pancreatitis - NSIM?
wait until pcitis subsided (usually by next day ) and amylase levels return to normal, then do c-cystectomy and cholangiography; if pt is ill, do ERCP first and relieve obstruction before ccystectomy
what is mandatory with biliary pcitis?
cholangiogram
severe illness due to acute pcitis 2ndary to biliary obstruction?
delay cholecystectomy; perform ERCP if need to remove stones obstructing cbd
gb with distension and fluid causing "internal echoes"? NSIM?
=gb empyema
do emergent exploration or percut cstomy for drainage of gb if health is poor
air in the biliary system, post -ccystectomy, and dilated bd's? NSIM?
think suppurative cholangitis.
tx = IV fluids, urgent decompression, ERCP WITH SPHINCTEROTOMY
type of pts that may manifest signs of SEPSIS with hypothermia and leukopenia?
elderly
cholangitis most often caused by?
choledocholithiasis
"retained" stone in cbd vs primary stone?
retained = seen <2yrs post c-cystectomy. primary = seen after 2 years
tx for choledocholithiasis OR cholangitis
ERCP with stone removal
followed by cholecystectomy
tx of biliary stricture (ie caused by past ccystectomy?
=surgical exploration and bypass with choledochojujenostomoy
NSIM in post -lapchol pt withfever and abd px, or with jaundice?
abd US
HIDA scan (hepatoiminodiacetic acid)
- detects biliary leaks
and acute cholecystitis
what if HIDA scan shows normal findings and no US findings of leak or collection?
follow pt
what does HIDA find?
biliary leaks, obstructed cystic ducts, and obstructed CBD's
if HIDA and ERCP finds leakage of bile duct, how treat?
treat by bile drainage (TEMPORARY) via stent via ERCP...later should do more definiteve tx such as ? (closing leakage with staple?)
if both HIDA and ERCP show complete bile duct obstruction? NSIM?
attemtp stone removal, if no repair possible, do choledochojejunostomy
PAINLESS jaundice with pruritis, direct bilirubinemia, normal lft's, and elevated alp?
think biliary tree obstruction due to:
pancr head cxr
periampullary cxr
cholangiocarc
stricture of CBD
cbd impaction in ampulla
what is klatskin tumor?
cholangiocarcinoma
in painless jaundice man, US sees dilated cbd but no gallstones or pancreatic masses...NSIM?
CT of abdomen
which is actually better, abd US or abd CT for visualizing DISTAL common duct area?
abd CT
if suspect pancr head cxr but see no mass on US or abd CT, what do next?
endoscopic ultrasound (through duod wall to see pancr head)
pre op findings that would make a pt with pancr cancer inoperative?
poor medical condition
distant mets present
neurologic sx or bone px
liver mets
sign of incurable disease in pancreatic cxr?
any distant mets, any invation into local structures ie portal vein, aorta, sma, etc
only indication for resection in pancr cxr?
localized lesion limted to pancr
first part of pancr cxr resection should be?
b/c ct may miss mets elsewehere, should first check pt/ omentum /ln's for mets....if seen, do frozen section and halt surgery if found to be cxr = indications for unresectability
5 year cure rate of pancr cxr after pancreatoduodenectomy? survival after only palliative surg (biliary stent and gastric bypass to prevent obstr)
10% only

8mo only
painless jaundice with no extrahepatic bd dilation or obstruction? NSIM?
think obstruction at hepatic duct level, ie KIlatskin tumor = tumor sof bil tree at bifurcation of hepatic ducts = cause intra not extrahepatic dilation.
NSIM = ERCP or ptca to demonstrate level of obstr; biopsy for dx of cholangiocarc (klatskin tumor)
are most klatskin tumors resectable or not?
most are not
5 yr survival rate for klatskin tumors?
15%
what is whipple's procedure?
pancreatoduodenectomy for ie pancr cxr, cholangiocarcinoma (klatskin tumor) or ampullary adenocarc,
does ampullary cxr have high or low cure rate?
has higher cure rate (65%) than pancr cxr
tx of gallbladder cxr?
open cholecystectomy with large 2-3cm margins resected into the liver and surrounding tissues;
small polyp <2cm in gb tx? larger?
small = observe
larger = cholecystectomy b/c may develop into adenocarc of gb
NSIM in acute epigastric pain, elevated amylase/lipase?
abd US --> if normal, -->?

then do obstructive abd series to r/o PERFORATION!!
tx of pancreatitis?
NPO, IV hydration, px control (NSAIDS) and observation
gallstone pancreatitis management?
manage pcitis, WAIT until passes, then do lap chol-ectomy
severe abd px + elev amylase --> progressing to hypotn, hyypoxia, and multiorgan failure? NSIM?
NECTROTIZING pcitis, with massive 3rd spacing due to pancr inflammation. + SIRS (severe inflamm response syndr) causing multi organ failure and eventually ARDS
NSIM = fluid resusc, ICU, CT abd, assess Ranson criteria for prognostic signs
what is SIRS?
'sepsis' without known infection
ranson criteria?
GA LAW in first 24 hrs
Gluc >200
Age > 55
LDH > 350
Ast > 250
Wbc > 16000

CHOBBS in 48 hrs
Ca <8mg/dL
Hmct decr by 10%
O2 (Pa02) <60 mm Hg
Base def >4 meq/L
BUN incr by 5mg/dL
Seq fluid >6 L

if 3 = 30% mort
if 5-6 = 40%
if 7-8 = 100%
do amylase levels correlate with severity ofr pancreatitis or prognosis?
No
way to evaluate for pancr abscess?
dynamic CT = contrast material timed to determinevfacularity of pancreas
pancr abscess suspected via CT tx?
confirm by percut US/CT guided sample and test for bact, then if so, drainage!!
older pt with abd px and increased amylase levels, suspect what?
either pancreatitis OR
mesenteric ischemia, OR volvulus could all manifest similarly; amylase is not specific enough
cause of early satiety in pt with persistent elevation of amylase and abd px, post acute pcitis?
PSEUDOCYST pressing on post wall of stomach!
dx of pseudocyst?
CT of abd, or US of abd
do you drain a pseudocyst? how tx?
no; just NPO, TPN, and observation unless signs of infection = AB's; or unless does not resolve with tx after 7 weeks = do surgery
what kind of surgery if after 7 weeks pseudocyst remains?
cystogastrostomy = drain cyst through post wall of stomach; as well as bx to ensure that cyst is not a cystadenom aor cystadenocarcinoma of pcreas
mass in liver in 37 y/old woman with ruq? what causes this?
cyst or
hemangioma = due to oc pills, enviro toxins, hep B and C, estrogen therapy, steroid therapy
simple liver cyst, NSIM?
no further managment if no sx f sx, aspiration
liver cyst with internal echoes? tx?
think echinococcal cyst;
do serolog tesst ofr echinococcus, then do injection of cyst with hypertonic saline, then excision of cyst...do not spill into pt, which can cause ptitis
fever, elev wbc ct, abd tenderness in RUQ, liver cyst, think?
ABCESS: tx = IV ab's and CT-guided drainage!!
amebic liver abcess, how to tx?
Don't need to drain, just give metronidazole
echinococcal cyst characteristics?
calcified outer wall, multilocular, internal echoes on US
90% of hepatic adenmoa pts have what hx?
OC usage ( as do hemangiomas)
how tx large hepatic adenoma? why?
resection
b/c risk of progression to HCC from malignant foci, and/or risk of rupture
hepatocellular carcinoma has what marker?
elevated alpha -FP
m/c solid liver mass in 37 y/0? dx?
hepatic hemangioma
dx via labeled RBC scan
types of liver lesions to remove?
symptomatic; risk of rupture; or uncertain dx lesions
how are most hemangiomas discovered?
during US for gstones
how treat hemangioma of liver?
if no sx, just observation.
tx of liver with focal nodular hyperplasia?
no tx necessary
what has a high risk of rupture during pregnancy and should therefor be resected before pregnancy?
hepatic adenoma!! (actually should first try to just stop OC's, since most will just regress w/o OC use)
NSIM when do bx and find HCC?
Staging by CT for mets to lung, abd, hilar ln's, etc
when is resection not warranted in liver hcc?
multiple lesions, or involvement of critical structure ie portal vn, IFC, hepatic vns
margins needed for a liver resection?
need 1 cm margins and need to preserve all vasculature
tx for multiple , small pyogenic abscesses of liver?
broad spectrum ABs for 4-6 weeks..only drain if large, single pyogenic abscess
liver amebic abscess tx?
Metronidazole alone, no need for drainage.
tx of liver abscess caused by e. histolytica?
this is amebic; tx with metronidazole only...no drainage necessary
45 y.o with crampy abd px, abvd distention, constip, and previous appendectomy...dx? NSIM?
sbo caused by strictures, although ileus could also do this
NSIM = abd series
what is an abd series for obstruction?
upright PA, lateral chest xray, flat and upright radiograph
radiograph of sbo?
multiple air fluid levels in SMALL bowel, no evicence of air in colon or rectum
elyte changes in sbo?
VOMITING causes loss of H, CL, NA, and h2o from stomach, causing contraction alkalosis, hypokalemia (H+ pulled out of cells, K+ pushed in), etc.
correction of sbo induced elyte abnorms?
give fluids + K+, then alkalosis will correct itself
in absence of marked lcytosis, fever, acidosis, or localized tendreness, how to manage SBO?
ydration, NG drainage and observation only...