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13 Cards in this Set

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cartilage
pliable and firm matrix, tensile strength

avascular, alymphatic, aneural
Cartilage cells
chondroblasts
chondrocyte
Chondroblasts
-immature
-at periphery of growing cartilage
-oval basophilic, in lacuna
-dividing cells and form matrices

Chondrocytes
-spherical nucleus, one or more nucleoli
-glycogen and lipid droplets in older chondrocytes
-can be more than one cell in a lacunae
Cartilage Matrix
-Ground substance and fibers
-type 2 collagen
Classification of Cartilage
Hyaline
Hyaline
-type 2 collagen fibers
periphery small chrondrocytes in elliptical lacunae running parallel to surface
-deep: large, polyhedral
-location trachea nose larynx bronchi on articulating surfaces
-pericellular, territorial, interterritorial
-perichondrium:
Chondrogenic and fibrous
Elastic
-wher elasticity and rigidity are needed
-few fibers near pericondrium, dense inner
-greater variation in lacunae size
Fibrocartilage
-least frequent
-type1 collagen fibers
-Rows of small lacunae with chondrocytes parallel to collagen bundles
-location tendons
Development of Cartilage
-origin mesenchymal
-cells cluster at center of chondrification
-secrete amorphous substance and type 2:
interstitial growth and appositional growth
Nutrition of Cartilage
-avascular, diffusion
-vascular channels penetrate if cartilage is thicker than 3mm
Characteristics of Bone
-firm less pliable than cartilage, cells and fibers embedded in hard unbending mineralized matrix
-vascular
-cantain bone marrow in medullary cavity
-dynamic
greatest tensile least weight
Osteoblasts
-role: active formation and mineralization of matrix
-deposits osteoid (collage 1 and proteoglycans)
-near surfaces
-basophilic cytoplasm
Osteocyte
-principal cell in bone
-maintain bone structure
-more lysosomes
-lacuna, extend processes in canaliculi
-removes osteocytic osteolysis and replaces perilacunar bone
Osteoclast
-large multinucleated
-resorb bone, secrete acid and lysosomal enzymes
Bone Matrix
-osteoid mineralized by deposition of hydroxyapaptite btw collagen fibers
-collagen fibers course spirally in each lamella of osteon