Supportive Tissues: Cartilage And Bone

Front 1

cartilage

Back 1

pliable and firm matrix, tensile strength

avascular, alymphatic, aneural

Front 2

Cartilage cells
chondroblasts
chondrocyte

Back 2

Chondroblasts
-immature
-at periphery of growing cartilage
-oval basophilic, in lacuna
-dividing cells and form matrices

Chondrocytes
-spherical nucleus, one or more nucleoli
-glycogen and lipid droplets in older chondrocytes
-can be more than one cell in a lacunae

Front 3

Cartilage Matrix

Back 3

-Ground substance and fibers
-type 2 collagen

Front 4

Classification of Cartilage
Hyaline

Back 4

Hyaline
-type 2 collagen fibers
periphery small chrondrocytes in elliptical lacunae running parallel to surface
-deep: large, polyhedral
-location trachea nose larynx bronchi on articulating surfaces
-pericellular, territorial, interterritorial
-perichondrium:
Chondrogenic and fibrous

Front 5

Elastic

Back 5

-wher elasticity and rigidity are needed
-few fibers near pericondrium, dense inner
-greater variation in lacunae size

Front 6

Fibrocartilage

Back 6

-least frequent
-type1 collagen fibers
-Rows of small lacunae with chondrocytes parallel to collagen bundles
-location tendons

Front 7

Development of Cartilage

Back 7

-origin mesenchymal
-cells cluster at center of chondrification
-secrete amorphous substance and type 2:
interstitial growth and appositional growth

Front 8

Nutrition of Cartilage

Back 8

-avascular, diffusion
-vascular channels penetrate if cartilage is thicker than 3mm

Front 9

Characteristics of Bone

Back 9

-firm less pliable than cartilage, cells and fibers embedded in hard unbending mineralized matrix
-vascular
-cantain bone marrow in medullary cavity
-dynamic
greatest tensile least weight

Front 10

Osteoblasts

Back 10

-role: active formation and mineralization of matrix
-deposits osteoid (collage 1 and proteoglycans)
-near surfaces
-basophilic cytoplasm

Front 11

Osteocyte

Back 11

-principal cell in bone
-maintain bone structure
-more lysosomes
-lacuna, extend processes in canaliculi
-removes osteocytic osteolysis and replaces perilacunar bone

Front 12

Osteoclast

Back 12

-large multinucleated
-resorb bone, secrete acid and lysosomal enzymes

Front 13

Bone Matrix

Back 13

-osteoid mineralized by deposition of hydroxyapaptite btw collagen fibers
-collagen fibers course spirally in each lamella of osteon