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32 Cards in this Set

  • Front
  • Back
Tyramine
indirect agonist (causes diffusion of norepinephrine)
Amphetamine
indirect agonist (causes diffusion of norepinephrine)
Cocaine
Blocks uptake 1 (neuronal uptake, counteracts indirect agonists)
Reserpine
Blocks vesicular uptake of dopamine (counteracts indirect agonists)
Ephedrine
Mixed agonist
Phenylephrine
alpha 1 agonist
Norepinephrine
alpha 1, alpha 2, beta 1 agonist
Epinephrine
alpha 1, alpha 2, beta 1, beta 2, beta 3 agonist
Dobutamine
beta 1 agonist (raise HR and contractility w/out changing TPR)
Terbutaline
beta 2 agonist (useful in asthma)
Dopamine
alpha 1 and beta 1 agonist
Clonidine
alpha 2 agonist (prevents release of NE by binding to the alpha 2 autoreceptor on nerve terminal)
Prazosin
alpha 1 blocker
Tamsulosin (Flomax)
alpha 1 blocker (relieve urinary retention in BPH)
Phenoxybenzamine
NON-COMPETITIVE alpha 1 blocker
Yohimbine
alpha 2 blocker
Phentolamine
alpha 1 and alpha 2 blocker
Metoprolol
beta 1 blocker
Atenolol
beta 1 blocker
Butoxamine
beta 2 blocker
timolol
beta 1 and beta 2 blocker
Propanolol
beta 1 and beta 2 blocker
Labetalol
Mixed antagonist. blocks both alpha and beta
Alpha 1 (mechanism, location, actions)
increase IP3, increase DAG
Most VSM - contraction
Pupillary dilator - contraction (dilates pupil)
Pilomotor SM - erects hair
Prostate - Contraction
Heart - Increases for of contraction
Alpha 2 (mechanism, location, actions)
Decrease cAMP
Postsynanptic CNS adrenoreceptors - inhibit release of NE (only thing hightlighted in class)
Beta 1 (mechanism, location, actions)
increase cAMP
Heart - increase force and rate of contraction
Beta 2 (mechanism, location, actions)
increase cAMP
Resp, uterine, anf vascular SM - promotes relaxation
Beta 3 (mechanism, location, actions)
increase cAMP
Fat cells - activate lipolysis
D1 (mechanism, location, actions)
increase cAMP
Renal smooth muscle - dilates renal BVs
D2 (mechanism, location, actions)
decrease cAMP
nerve endings - modulates transmitter release
Methoxamine
alpha 1 agonist
Albuterol
beta 2 agonist (good for asthma)