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10 Cards in this Set
- Front
- Back
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What are the DSM criteria for Substance-Induced Psychotic Disorder?
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A) Psychosis - prominent delusions or hallucinations
B) Evidence that psychotic symptoms developed during or within a month of intoxication or withdrawal C) Disturbance not better accounted for by another psychotic disorder D) Disturbance not part of a delirium syndrome |
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What are "uppers"? How do they work?
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"Uppers" are neurostimulants
Examples: -Amphetamine -Dextroamphetamine (Adderall) -Methamphetamine (speed, crystal meth) -Methylphenidate Neurostimulants work through blocking reuptake of monoamines (dopamine, serotonin, noradrenaline) or as releasing agents of these neurotransmitters. |
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What is khat?
What is the psychoactive compound found in khat? |
Khat (Catha edulis) is a flowering plant native to the Horn of Africa and the Arabian Pensinsula.
Cathinone, an amphetamine-like stimulant, is the psychoactive compound found in khat. |
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What is the scientific name for the khat plant?
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Catha edulis
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What is the mechanism of action behind cocaine's anesthetic propeties?
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Cocaine prevents the activation of Na+ channels required for depolarization
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What is the mechanism of action of cocaine?
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Cocaine blocks the reuptake of biogenic amines (monoamines). It blocks the reuptake of dopamine, serotonin, and noradrenaline, inreasing synaptic levels of these neurotransmitters.
The blockade of noradrenaline reuptake results in a sympathomimetic effect. |
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What is the mechanism of action of methamphetamine?
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Methamphetamine is a potent releasing agent of biogenic amines, including epinephrine, norepinephrine, dopamine, and serotonin.
Methamphetamine is incorporated into cytoplasmic vesicles where it displaces these neurotransmitters into the synapse. |
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What is the mechanism of action of MDMA?
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MDMA is a monoamine releasing agent (like methamphetamine) and a monoamine reuptake inhibitor (like cocaine)
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What is the withdrawal syndrome for neurostimulants?
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Dysphoric mood plus 2 of the following:
Fatigue Increased appetite Hypersomnia Psychomotor retardation |
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Describe the neurostimulant toxidrome:
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VITALS:
Increased heart rate Increased blood pressure MIND: Psychomotor agitation HEAD: Mydriasis SKIN: Diaphoresis CARDIOVASCULAR: Arrhythmia GI: Nausea/vomiting |
