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25 Cards in this Set
- Front
- Back
648. How prevalent is alcoholism?
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a. 10-15% of people have alcoholism (alcohol abuse or dependence).
b. There is a genetic component to alcoholism!!! i. Close relatives of alcoholics (especially sons) are at increased risk for alcoholism. |
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649. Screening for alcoholism?
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a. Ask all pts about alcohol use. If alcoholism is suspected, use one of the following screening methods
b. CAGE (any more than 1 positive answer may suggest alcohol abuse) c. MAST (Michigan Alcoholism Screening Test) Questionnaire- 25-item questionnaire that also helps identify alcoholism. |
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650. CAGE questions?
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a. Cut down? (have you ever felt need to cut down)
b. Annoyed? (Ever felt annoyed by criticisms of your drinking). c. Guilty? Ever felt guilt about drinking d. Eye-opener? Ever taken a morning eye-opener. |
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651. Alcohol and lipid levels?
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a. Modest alcohol intake (max 1-2 drinks per day) is associated w/an increase in HDL.
b. On the other hand, alcohol increases TG levels. |
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652. 4 symptoms of alcohol withdrawal?
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a. Tachycardia
b. Sweating c. Anxiety d. Hallucinations. |
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653. Goal in treating alcohol withdrawal?
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a. To prevent progression to DTs, which is a medical emergency (mortality rate, 20%)
i. DTs occur in 5% of alcoholic withdrawals. |
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654. DT?
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a. DT is delirium develop-ing w/in a week of last alcoholic intake, usually 2-4 days after the last drink.
b. DT is characterized by: 1. tactile hallucinations 2. Visual hallucinations 3. Confusion 4. Sweating 5. ↑d tachycardia 6. Elevated BP. |
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655. Risk factors for developing DTs w/alcohol withdrawal?
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1. Pancreatitis
2. Hepatitis 3. Other illness b. DT is rare in healthy people. |
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656. Tx of alcohol withdrawal?
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a. Give BZDs if withdrawal symptoms are present.
b. Prevention of DT is the best tx. c. Diet is important in tx: 1. High in calorie 2. High in carbs 3. Multivitamins. |
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657. Complications of alcoholism-systems overview?
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a. GI
b. Cardiac c. CNS d. Pulmonary e. Nutritional deficiencies. f. Peripheral neuropathy g. Sexual dysfunction- impotence, loss of libido h. Psych- depression, anxiety, insomnia. i. ↑d frequency of malignancy- oesophagus, oral, liver, lung j. Frequent falls, minor injuries, motor vehicle accidents!!! |
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657. Complications of alcoholism-systems overview?
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a. GI
b. Cardiac c. CNS d. Pulmonary e. Nutritional deficiencies. f. Peripheral neuropathy g. Sexual dysfunction- impotence, loss of libido h. Psych- depression, anxiety, insomnia. i. ↑d frequency of malignancy- oesophagus, oral, liver, lung j. Frequent falls, minor injuries, motor vehicle accidents!!! |
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658. GI complications of alcohol?
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a. Gastritis
b. Oesophagitis c. Peptic ulcer disease d. Alcoholic liver disease (alcoholic hepatitis, cirrhosis, portal HTN) e. Pancreatitis (acute and chronic) f. Mallory-Weiss tears |
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659. Cardiac complications of alcohol?
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a. Alcoholic cardiomyopathy
b. Essential HTN (more than 3 drinks per day significantly increases BP) |
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660. CNS complications of alcohol?
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a. Wernicke’s encephalopathy
b. Korsakoff’s encephalopathy |
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661. Wernicke’s encephalopathy-cause?
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a. Often reversible
b. Caused by thiamine deficiency |
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662. Wernicke’s encephalopathy symptoms?
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a. Nystagmus
b. Ataxia c. Ophthalmoplegia d. Confusion |
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663. Korsakoff’s encephalopathy cause?
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a. Thiamine deficiency
b. Irreversible |
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664. Korsakoff’s encephalopathy symptoms?
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a. Alcohol-induced amnestic disorder
b. Mostly affects short-term memory c. Confabulation is common. |
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665. Pulmonary complications of alcohol?
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a. Pneumonia
b. Aspiration |
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666. Nutritional complications of alcohol?
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a. Especially thiamine deficiency
b. Hypomagnesemia c. Folate deficiency |
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667. Pathophys of peripheral neuropathy as a complication of alcohol?
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a. Due to thiamine deficiency.
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668. Lab findings in alcoholics?
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a. Anaemia
b. Macrocytic (most common)- due to folate deficiency c. Microcytic-due to GI bleeding d. LFTs: ↑ GGT, AST:ALT is 2:1 e. Hypertriglyceridemia f. Hyperuricemia, hypocalcemia g. Thiamine deficiency h. ↓d testosterone level. |
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669. Tx of Alcoholism?
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a. AA is best tx.
b. Disulfiram (Antabuse) c. Naltrexone (Trexan) d. Drugs for withdrawal: Benzos- best to use long-acting agents (diazepam) e. Correction of fluid imbalance, vitamin supplementation (thiamine, folate, multivitamins). |
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670. Effect of Disulfiram (Antabuse)?
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a. a few minutes after drinking alcohol, pt experiences SOB, flushing, palpitations, tachycardia.
b. If more alcohol is taken, HA and N/V ensue. c. Symptoms last about 90 minutes. d. It is appropriate for short-term use and should not be taken chronically. e. Routine f/u is important. |
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671. Effect of Naltrexone (Trexan)?
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a. This has been shown to improve abstinence rates.
b. It reduces the craving for alcohol. |