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25 Cards in this Set

  • Front
  • Back
648. How prevalent is alcoholism?
a. 10-15% of people have alcoholism (alcohol abuse or dependence).
b. There is a genetic component to alcoholism!!!
i. Close relatives of alcoholics (especially sons) are at increased risk for alcoholism.
649. Screening for alcoholism?
a. Ask all pts about alcohol use. If alcoholism is suspected, use one of the following screening methods
b. CAGE (any more than 1 positive answer may suggest alcohol abuse)
c. MAST (Michigan Alcoholism Screening Test) Questionnaire- 25-item questionnaire that also helps identify alcoholism.
650. CAGE questions?
a. Cut down? (have you ever felt need to cut down)
b. Annoyed? (Ever felt annoyed by criticisms of your drinking).
c. Guilty? Ever felt guilt about drinking
d. Eye-opener? Ever taken a morning eye-opener.
651. Alcohol and lipid levels?
a. Modest alcohol intake (max 1-2 drinks per day) is associated w/an increase in HDL.
b. On the other hand, alcohol increases TG levels.
652. 4 symptoms of alcohol withdrawal?
a. Tachycardia
b. Sweating
c. Anxiety
d. Hallucinations.
653. Goal in treating alcohol withdrawal?
a. To prevent progression to DTs, which is a medical emergency (mortality rate, 20%)
i. DTs occur in 5% of alcoholic withdrawals.
654. DT?
a. DT is delirium develop-ing w/in a week of last alcoholic intake, usually 2-4 days after the last drink.
b. DT is characterized by:
1. tactile hallucinations
2. Visual hallucinations
3. Confusion
4. Sweating
5. ↑d tachycardia
6. Elevated BP.
655. Risk factors for developing DTs w/alcohol withdrawal?
1. Pancreatitis
2. Hepatitis
3. Other illness
b. DT is rare in healthy people.
656. Tx of alcohol withdrawal?
a. Give BZDs if withdrawal symptoms are present.
b. Prevention of DT is the best tx.
c. Diet is important in tx:
1. High in calorie
2. High in carbs
3. Multivitamins.
657. Complications of alcoholism-systems overview?
a. GI
b. Cardiac
c. CNS
d. Pulmonary
e. Nutritional deficiencies.
f. Peripheral neuropathy
g. Sexual dysfunction- impotence, loss of libido
h. Psych- depression, anxiety, insomnia.
i. ↑d frequency of malignancy- oesophagus, oral, liver, lung
j. Frequent falls, minor injuries, motor vehicle accidents!!!
657. Complications of alcoholism-systems overview?
a. GI
b. Cardiac
c. CNS
d. Pulmonary
e. Nutritional deficiencies.
f. Peripheral neuropathy
g. Sexual dysfunction- impotence, loss of libido
h. Psych- depression, anxiety, insomnia.
i. ↑d frequency of malignancy- oesophagus, oral, liver, lung
j. Frequent falls, minor injuries, motor vehicle accidents!!!
658. GI complications of alcohol?
a. Gastritis
b. Oesophagitis
c. Peptic ulcer disease
d. Alcoholic liver disease (alcoholic hepatitis, cirrhosis, portal HTN)
e. Pancreatitis (acute and chronic)
f. Mallory-Weiss tears
659. Cardiac complications of alcohol?
a. Alcoholic cardiomyopathy
b. Essential HTN (more than 3 drinks per day significantly increases BP)
660. CNS complications of alcohol?
a. Wernicke’s encephalopathy
b. Korsakoff’s encephalopathy
661. Wernicke’s encephalopathy-cause?
a. Often reversible
b. Caused by thiamine deficiency
662. Wernicke’s encephalopathy symptoms?
a. Nystagmus
b. Ataxia
c. Ophthalmoplegia
d. Confusion
663. Korsakoff’s encephalopathy cause?
a. Thiamine deficiency
b. Irreversible
664. Korsakoff’s encephalopathy symptoms?
a. Alcohol-induced amnestic disorder
b. Mostly affects short-term memory
c. Confabulation is common.
665. Pulmonary complications of alcohol?
a. Pneumonia
b. Aspiration
666. Nutritional complications of alcohol?
a. Especially thiamine deficiency
b. Hypomagnesemia
c. Folate deficiency
667. Pathophys of peripheral neuropathy as a complication of alcohol?
a. Due to thiamine deficiency.
668. Lab findings in alcoholics?
a. Anaemia
b. Macrocytic (most common)- due to folate deficiency
c. Microcytic-due to GI bleeding
d. LFTs: ↑ GGT, AST:ALT is 2:1
e. Hypertriglyceridemia
f. Hyperuricemia, hypocalcemia
g. Thiamine deficiency
h. ↓d testosterone level.
669. Tx of Alcoholism?
a. AA is best tx.
b. Disulfiram (Antabuse)
c. Naltrexone (Trexan)
d. Drugs for withdrawal: Benzos- best to use long-acting agents (diazepam)
e. Correction of fluid imbalance, vitamin supplementation (thiamine, folate, multivitamins).
670. Effect of Disulfiram (Antabuse)?
a. a few minutes after drinking alcohol, pt experiences SOB, flushing, palpitations, tachycardia.
b. If more alcohol is taken, HA and N/V ensue.
c. Symptoms last about 90 minutes.
d. It is appropriate for short-term use and should not be taken chronically.
e. Routine f/u is important.
671. Effect of Naltrexone (Trexan)?
a. This has been shown to improve abstinence rates.
b. It reduces the craving for alcohol.