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30 Cards in this Set

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59. Clinical features of Acute Bronchitis?
a. Cough (w/ or w/o sputum) is the predominant symptom!!! It lasts 1-2 weeks.
i. In a significant number of pts, the cough may last for 1 month or longer.
ii. Chest discomfort and SOB may be present.
iii. Fever may or may not be present.
60. Tx of Acute bronchitis?
a. Abx are usually NOT necessary- most cases are viral.
b. Cough suppressants (codeine-containing meds) are effective for symptomatic relief.
c. Bronchodilators (albuterol) may relieve sx.
61. What does susceptibility to common cold depend on?
a. Pre-existing antibody levels.
62. Causes of common cold?
a. Rhinovirus is most common (at least 50% of cases)- there are more than 100 antigenic serotypes, so reinfection w/another serotype can lead to symptoms (no cross-immunity among serotypes).
b. Other viruses include: coronovirus, parainfluenza virus (types A, B, and C), adenovirus, coxsackie, and RSV.
63. Most common route of transmission of cold!?!?!?!?!?!
a. Hand-to-hand transmission.
64. Progression of common cold?
a. Most resolve w/I 1 week, but symptoms may last up to 10-14 days.
65. Presentation of common cold?
a. Rhinorrhea
b. Sore throat
c. Malaise
d. Nonproductive cough
e. Nasal congestion.
f. Fever is uncommon in adults (suggests a bacterial complication or influenza), but is not unusual in children.
66. Tx of cold?
a. Symptomatic
b. Adequate hydration
i. Loosens secretions and prevents airway obstruction
ii. Can be achieved by increasing fluid intake and inhaling steam.
c. Rest and analgesics (aspirin, acetaminophen, ibuprofen) – for relief of malaise, HA, fever, aches.
d. Cough suppressant (dextromethorphan, codeine).
e. Nasal decongestant spray (Neo-Synephrine) for less than 3 days.
f. Oral first-gen antihistamines for rhinorrhea/sneezing.
67. What features occur in both bacterial sinusitis and viral rhinosinusitis?
a. Sneezing/rhinorrhea
b. Nasal d/c (whether clear, purulent, or coloured)
c. Nasal obstruction
d. Facial pain/HA
68. Note: Many of the symptoms that occur w/the common cold are also seen in influenza but are more severe in the latter. Fever, HA, myalgias, and malaise are much more pronounced w/the flu.
68. Note: Many of the symptoms that occur w/the common cold are also seen in influenza but are more severe in the latter. Fever, HA, myalgias, and malaise are much more pronounced w/the flu.
69. Sinusitis?
a. Inflammation of the lining of the paranasal sinuses, often due to infection.
b. Mucosa oedema obstructs the sinus openings (ostia), trapping sinus secretions.
70. Pathophys of acute sinusitis?
a. Most cases occur are a complication of common cold or other URIs (However, fewer than 1% of URIs lead to acute sinusitis).
b. May also be caused by nasal obstruction due to polyps, deviated septum, or foreign body.
71. What is acute bacterial sinusitis most commonly due to?
1. Strep pneumoniae
2. Haemophilus
3. Anaerobes
b. Other types: viral, fungal, or allergic.
72. Most commonly involved sinuses w/acute sinusitis?!?
a. Maxillary.
73. Presentation of Acute sinusitis?
a. Nasal stuffiness, purulent nasal discharge, cough.
b. Sinus pain or pressure (location depends on which sinus is involved)-pain worsens w/percussion or bending head down).
74. Maxillary sinusitis (most common) presentation?
a. Pain over cheeks that may mimic pain of dental caries!!!
75. Frontal sinusitis presentation?
a. Pain over lower forehead.
76. Ethmoid sinusitis presentation?
a. Retro-orbital pain
b. Or
c. Pain in upper lateral aspect of nose
77. Chronic sinusitis?
a. Nasal congestion, postnasal d/c.
b. Pain and HA are usually mild or absent.
c. Fever is uncommon.
d. By definition: Symptoms should be present for at least 2-3 months.
78. Aetiologies of Chronic sinusitis?
a. In addition to the organisms listed for acute sinusitis, pts w/a hx of multiple sinus infections (and courses of abx) are at risk for infection w/staph aureus and gram-negative rods.
79. Diagnosis of sinusitis?
a. Diagnosis is based on clinical findings. Consider acute bacterial sinusitis if a pt has a cold for more than 8-10 days or has prolonged nasal congestion.
b. PE: Look for purulent d/c draining from one of the turbinates.
c. Perform transillumination of maxillary sinuses (note impaired light transmission)- the room must be completely dark w/a strong w/a strong light source.
d. Palpate over the sinuses for tenderness (not a reliable finding).
80. Imaging studies for sinusitis?
a. Usually not indicated in routine community-acquired infections.
b. A CT scan (coronal view) is superior to plain radiograph.
c. It should be performed in complicated disease of if surgery is being planned.
81. Complications of sinusitis?
a. Mucocele, polyps
b. Orbital cellulites-Usually originating from ethmoid sinusitis.
c. Osteomyelitis of frontal bones or maxilla
d. Cavernous sinus thrombosis (rare)
e. Very rare: epidural abscess, subdural empyema, meningitis, and brain abscess-due to contiguous spread through bone or via venous channels.
82. From what type of sinusitis does Orbital cellulitis usually originate?
a. ethmoid sinusitis.
83. General measures/advice for pt w/acute purulent sinusitis?
a. Saline Nasal spray aids drainage
b. Avoid smoke and other environmental pollutants
84. Tx of acute purulent sinusitis (4 things)?
a. Decongestants
b. Abx
c. Antihistamines
d. Nasal steroids
85. 2 decongestants for acute purulent sinusitis and MOA?
1. Pseudoephedrine
2. Oxymetazoline
b. Facilitate Sinus drainage!!!! And relieve congestion
c. Available in both topical and systemic preps.
d. Give for no more than 3-5 days.
86. Abx for acute purulent sinusitis?
a. Amoxicillin
b. Amoxicillin-clavulanate (Augmentin)
c. TMP/SMX
d. Levofloxacin
e. Moxifloxacin
f. Cefuroxime
87. Course of abx for acute purulent sinusitis?
a. Tx for 1-2 weeks, depending on severity.
b. If there is no improvement after 2 weeks of therapy, then sinus films and a penicillinase-resistant abx are appropriate.
c. Consider ENT consult.
d. Bc of the anatomic difficulties of drainage, the course of acute sinusitis takes longer to resolve than other URIs.
88. Antihistamines for tx of acute purulent sinusitis?
a. Reserve for pts w/allergies; use discriminately bc of “drying effect”
b. Loratadine, fexofenadine, chlorpheniramine (Chlortrimenton).