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23 Cards in this Set

  • Front
  • Back
What is an observational study?
a study that
-observes the subject in the real world
-there is no intervention
What is an experimental study?
a study that
-does more than observe subjects
-treats, vaccinates and infects subjects
-in a controlled setting
--may or may not be in a lab
--clinical trials in feedlots
What are examples of observational studies?
case report/series
cross-sectional
Ecological
Case Control
Cohort
What are examples of experimental studies?
clinical trials
What is a prospective study?
a study that
-looks forward in time
-follows study subjects forward in time
What is a retrospective study?
a study that
-looks back in time
-look for characteristics or events that happen to study subject in the past
What are examples of prospective studies?
Clinical trials
Prospective cohorts
What are examples of retrospective studies?
case report/series
cross sectional
ecological
Case-control
Retrospective
What is a descriptive test?
no hypothesis
describes the disease and characterize the disease frequency, distribution, who it affects and seasonality
What is a hypothesis test?
identify or test a hypothesis
association between exposure and disease outcome
What is an example of descriptive testing?
case studies/series
some cross sectional studies
What are examples of Hypothesis testing?
ecological
some cross sectional
case control
cohort
clinical trials
What is the difference between case reports and case series studies?
both describe

reports are about one animal
series are about a small number of serveral animals

both:
-document the first notice of a new disease
-describe a unique clinical presentation
-describe a novel therapeutic approach
What are ecological studies?
compares characteristics of populations

-disease and exposures are measured at the population level
-individuals are not studied or sampled

populations can be defined
-by region, country, state or city
-by housing group
- by time (before or after intervention)
What are cross sectional studies?
study based on a sample of individuals from the population

-by random or convenience
What is an example of a random cross sectional study?
a random survey of dog owners in a city to determine how many are spayed/neutered VS intact
What is an example of a convenience cross sectional study?
a survey of dog seen in a city to determine how many are spayed/neutered VS intact
What are two types of cross sectional studies?
prevalence studies
association studies
What is a prevalence study?
type of cross-sectional study that
estimates the amount or the distribution of disease (where. who, seasonality)

select subjects that are representative of the population and measure whether they are diseased or not
What is an association study?
a type of cross sectional study that estimates an association between exposure and outcome
What are case control studies?
When subjects are selected based upon their disease status

cases - with the disease be studied
control- without the disease
subjects exposures are assesed
retrospectively by reviewing animal records and survey questions

-the number of cases with the exposure to the number of controls with exposure
What is a cohort study?
number of individuals with something in common

subjects are selected based upon their exposure status

non-exposed (controls) with no exposure

the disease status of the two controls determined retrospectively or prospectively

compare number of exposed with disease to the number of non exposed with disease
Overall what are the purposes of case studies/senses
Ecological
cross sectional
case control
cohort
and experimental studies?
case studies/sense - 1st cases of the disease

ecological - no subjection selection

cross-sectional - select from the population

case-control studies - select by disease starus

Cohort studies - select by exposure status

Experimental studies - clinical trials = not selected
subjects are randomly allocated into a group