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11 Cards in this Set
- Front
- Back
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General characteristics
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-gram +
-facultative anaerobe -Beta hemolytic -catalase (-) |
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transmission
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oropharygeal area
spread by being aerosolized causes strep throat |
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Virulence Determinants
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-cell associated antigens
-M Proteins -Lipoteichoic acid -Hyaluronic Acid - F protein - Protein G |
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cell associated antigens
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carbohydrate antigen
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M proteins
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-binds to keratinocytes and fibrinogen
-blocks complement activation (factor H--serum protein--too much factor H binds to C3b and it degrades it) |
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Extracellular Products
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-Hemolysin
-streptokinase -C5a peptidase -hyaluronidase -DNase -Strep./pyrogenic exotoxins |
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Clinical Pres: Non-toxigenic
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-pharyngitis
-erysipelas -impetigo -puerperal Fever -severe invasive strep disease |
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Clical pres: Toxigenic
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-Scarlet Fever
-Strep. Toxic Shock Syndrome -Necrotizing fasciitis |
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Poststreptococcal Sequelae
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-Rheumatic fever
-Glomerulonephritis (Bright's Disease) |
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Diagnosis
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-gram-stain
-plate on Beta hemolysins, taxos A sensitivity, catalase - -aso test |
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treatment
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-amoxycillan
-erthomycin -no vaccine b/c too many M proteins |
