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11 Cards in this Set

  • Front
  • Back
General characteristics
-gram +
-facultative anaerobe
-Beta hemolytic
-catalase (-)
transmission
oropharygeal area
spread by being aerosolized
causes strep throat
Virulence Determinants
-cell associated antigens
-M Proteins
-Lipoteichoic acid
-Hyaluronic Acid
- F protein
- Protein G
cell associated antigens
carbohydrate antigen
M proteins
-binds to keratinocytes and fibrinogen
-blocks complement activation (factor H--serum protein--too much factor H binds to C3b and it degrades it)
Extracellular Products
-Hemolysin
-streptokinase
-C5a peptidase
-hyaluronidase
-DNase
-Strep./pyrogenic exotoxins
Clinical Pres: Non-toxigenic
-pharyngitis
-erysipelas
-impetigo
-puerperal Fever
-severe invasive strep disease
Clical pres: Toxigenic
-Scarlet Fever
-Strep. Toxic Shock Syndrome
-Necrotizing fasciitis
Poststreptococcal Sequelae
-Rheumatic fever
-Glomerulonephritis (Bright's Disease)
Diagnosis
-gram-stain
-plate on Beta hemolysins, taxos A sensitivity, catalase -
-aso test
treatment
-amoxycillan
-erthomycin
-no vaccine b/c too many M proteins