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11 Cards in this Set

  • Front
  • Back
Streptococcus ECM toxin
Streptokinase = fibrinolysin
Streptodornase = Hydrolyze DNA
Hyaluronidase = spreading factor
Pyogenic exotoxin = superantigen
Hemolysin: Streptolysin
O = oxygen labile, antigen
ASO titer = disease course
S = oxygen stable, non antigen
Streptococcus Virulence
No strep has following:
Catalase, oxidase, motility, spores
C-substance = resist phag
M Protein = breaks C3 convertase, Rheumatogenic
Protein F = Fibronectin binding
Lipoteichoic acid = adherence
Streptococcus Pyogenes
Beta hemolytic
Lancefield Group A
Pharyngitis, Pyoderma (impetigo)
Scarlet fever = Erythrogenic toxin
Erysipelas = vesicular eruptions
Necrotizing Fasciitis
Toxic Shock = Bacteremia
Rheumatic fever = M type autoimm
Glomerulonephritis = IC deposition
Streptococcus Pheumoniae
Alpha hemolytic
Diplococcal
Virulence: Capsule, Pneumolysin O
Optochin inhibits
Bile salt soluble
Quellung reaction for strains
Cause: Pneumonia, Meningitis, AOM
Enterococcus Faecalis
Lancefield Group D
Grows in high salt & bile
Antibiotic resistant
Endogenous infection
UTI & intravasc catheter
Wound infection
Treat: Aminoglycoside + cell wall
VRE = vanco resist, transferrable
Streptococcus Agalactiae
Lancefield Group B
Beta hemolytic
Infant = Meningitis
Adult = UTI
Common = Bacteremia, Pneumonia
ID = hydrolyze hippurate, +cAMP
Narrow beta hemolysis
Streptococcus Viridans
Alpha hemolytic
Infect damaged valves
Oral flora
Neisseria Gonorrhoeae
G- Intracellular diplococci
Non hemolytic = chocolate agar
Thayer-Martin selective media
= Vanco, Colistin, Nystatin
Oxidase and Catalase positive
Aerobic, likes high CO2
No exotoxins
Pili for attachment
Outer Membrane Protein = invasion
Por Proteins = Prevent phagolysosome fusion, attach/invade, protect from Ab
LOS = lipid A (gives symptoms)
IgA protease
Beta lactamase
Neisseria Meningitidis
(meningococcus)
Thayer-Martin or Chocolate agar
G- diplococci
Type 4 pili = breach meninges

Meningococcemia:
Septicemia and petechiae/purpura
May have meningitis

Meningococcal meningitis:
Stiff neck, nausea, vomit, headache
High mortality

Gram stain CSF, culture blood
Capsule B and C most virulent
Moraxella Catarrhalis
G- diplococci
Beta lactamase
Lung infection
Otitis media
Kingella Kingae
Oxidase positive
G- diplococci/coccobacillus
Fastidious
Oral flora
Bone, joint, tendon infection
Introduced by toothbrushing