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13 Cards in this Set
- Front
- Back
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BRAS
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B resisteant A sensitive (to bacitracin)
or is it s-pneumo is sensitive, whilst viridans is resistant???? |
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strep A skin infections spread more rapidly than stap aureus skin infections due to...?
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s-aureus has coagulase, which barrs off against migration
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SMASHED
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STREP A VIRULENCE FACTORS: SMASHED
STREP A: M protein Anti-C5a peptidase Streptokinase Hyaluronidase Exotoxin DNAses |
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NIPPLES
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strep A diseases = NIPPLES
Necrotising fasciitis and myositis Impetigo Pharyngitis Pneumonia Lymphangitis Erysipelas and cellulitis Scarlet fever/ Streptococcal TSS AS WELL AS: GN-itis (type II hypersensitivity) - pulmonary hypertension and edema Rheumatic fever 2 weeks after - (type II hypersensitivity) fever, arthritis, carditis, erythema marginatum, chorea |
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treatment of group A strep?
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beta lactams (or macrolides in case of PCN allergy)
we use ATB prophylaxis should be considered in patients who've had rheumatic fever at least 5 years post RF! |
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treatment of group B strep?
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we treat B positive mothers with ampicillin w/ AG at birth, or with cephalosporin (cephalosporins are safer!)
clinda or erythro for PCN allergy patients |
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what is the halo around the strep pneumonia on gram stain?
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the capsule!
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predisposing factors for strep pneumo infections?
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antecedent viral infection
COPD CHF alcoholism asplenia |
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which organisms have IgA protease?
which organisms |
nn
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strep pneumo is most common cause of which 4 diseases?
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typical, lobar, pneumonia - rusty (bloody) sputum, chills and fever (especially in old people)
adult meningitis: (peptidoglycan and techoic acids highly inflammatory in CNS otitis media and sinusitis in children |
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which test is best for strep pneumo?
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latex particle agglutination to test for capsular organisms in CSF (quellung is out of date!)
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treatment for strep pneumo?
prevention? |
pneumonia: macrolides
meningitis: always safer with ceph (e.g. ceftriaxone), vacomycin if resistant to PCNs! otitis media, sinusitis: amoxi, erythro prevention: vaccine: PCV: (capsular: for children) recommended for all children. this does not prevent all types of strep pneumo infections, but it prevents the 7 most virulent serotypes. i think we dont vaccinate for all, because that would hamper immune system development. PPV: polysaccharide for adults (for elderly, or at risk-patients) 23 serotypes to people with decling immunity! |
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transmission of viridans?
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endogenous (from oral flora)
e.g. mutans = caries sanguis: cause subacute endocarditis (which others?`caus Subacute?) prophylaxis before dental surgery! |
