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43 Cards in this Set

  • Front
  • Back
the flow of energy in a biological system; the conversion of macronutrients into biologically usable forms of energy.
bioenergetics
the breakdown of large molecules into smaller molecules, associated with the release of energy
catabolism
the synthesis of larger molecules from smaller molecules; can be accomplished using the energy released from catabolic reactions
anabolism
energy-releasing reactions that are generally catabolic
exergonic reactions
require energy and include anabolic processes and the contraction of muscle.
endergonic reactions
the total of all the catabolic or exergonic and anabolic or endergonic reactions in a biological system
metabolism
Allows the transfer of energy from exergonic to endergonic reactions.
Adenosine triphosphate (ATP)
Macronutrients (3)
carbs, fats, protein
Micronutrients (2)
vitamins and minerals
Systems that replenish ATP in muscle cells (3)
Phosphagen system, glycolysis, oxidative system
ATP-PcR
Adenosine triphosphate-Phosphocreatin
1-1 ratio
Glycolysis breakdown (2)
Anaerobic glycolysis-> fast glycolysis-> 1-2 or 3 ATP
Aerobic-> slow glycolysis-> 1 carb.= 40ATP
1 fat= 463 ATP
Provides ATP primarily for short-term, high- intensity activities and is active at the start of all exercise regardless of intensity
Phosphagen system
Uses ATP stored in muscles
Lasts about 10 sec
Ex.) Olympic Sprinters
ATP Stores (4)
The body does not store enough ATP for exercise.
Some ATP is needed for basic cellular function.
The phosphagen system uses the creatine kinase reaction to maintain the concentration of ATP.
The phosphagen system replenishes ATP rapidly.
The breakdown of carbohydrates-either glycogen stored in the muscle or glucose delivered in the blood-to resynthesize ATP
Glycolysis
The end result of glycolysis
pyruvate
The two directions that pyruvate goes
1. converted to lactate
2. shuttled into the mitochondria
Where does lactate get converted to glucose?
Liver
Cori Cycle
Lactate being transported in the blood to the liver where it is converted to glucose
Does the Cori System ever stop?
No- because the muscle works faster than the liver, causing lactate from the muscle to remain in the blood.
Energy yield of glycolysis (2)
1. Glycolysis from one molecule of blood glucose yields a net of 2 ATP.
2. Glycolysis from the glycogen yields a net of three ATP
ATP lasts about 30 sec-1 min
Lactate Threshold (LT)
represents an increasing reliance on anaerobic mechanisms, and often used as a marker of the anaerobic threshold.
The exercise intensity or relative intensity at which blood lactate begins an abrupt increase above the baseline concentration.
Lactate Threshold (LT)
OBLA
Onset of Blood lactate accumulation
Oxidative (Aerobic) system
primary source of ATP at rest and during low-intensity activities.
Uses primarily carbohydrates and fats as substrates
Metabolism of blood glucose and muscle glycogen begins with glycolysis and leads to the Krebs cycle. (If oxygen is present in sufficient quantities, the end product of glycolysis, pyruvate, is not converted to lactate but is transported to the mitochondria where it is taken up and enters the Krebs cycle.)
Glucose and Glycogen Oxidation
Triglycerides stored in fat cells can be broken down by hormone-sensitive lipase. This releases free fatty acids from the fat cells into the blood, where they can circulate and enter muscle fibers.
Fat Oxidation
Free fatty acids enter the mitochondria, are broken down, and form acetyl-CoA and hydrogen protons.
Fat Oxidation
Protein is broken down into amino acids, and the amino acids are converted into glucose, pyruvate, or various Krebs cycle intermediates to produce ATP.

Protein is not a significant source of energy for most activities
Protein Oxidation
Phosphagen depletion
decreases 50-70% during the first stage (5-30 sec) of high-intensity exercise and can be almost eliminated as a result of very intense exercise to exhaustion.
Phosphagen repletion
can occur in a relatively short period; complete resynthesis of ATP appears to occur within 3-5 min, and complete creatine phosphate resynthesis within 8 min.
Glycogen depletion
At relative intensities of exercise above 60% of maximal oxygen uptake, muscle glycogen becomes an increasingly important energy substrate; the entire glycogen content of some muscle cells can become depleted during exercise.
Glycogen repletion
optimal if .7-3.0 g of carbohydrate per kg of body weight is ingested every 2 hrs following exercises
VO2 (max)
75% of maximal oxygen uptake
EPOC
excess postexercise oxygen consumption
VO2
oxygen uptake or volume of oxygen
Excess postexercise oxygen consumption (EPOC)
Oxygen uptake above resting values used to restore the body to the preexercise condition; also called postexercise oxygen uptake, oxygen debt, or recovery O2
Anaerobic glycolysis
lasts about 45s
Aerobic glycolysis
has no known end point
fast glycolysis
goes through Cori cycle
slow glycolysis
goes through Krebs Cycle
pyruvate to liver
Cori Cycle
Pyruvate to mitochondria
Krebs Cycle