Study your flashcards anywhere!

Download the official Cram app for free >

  • Shuffle
    Toggle On
    Toggle Off
  • Alphabetize
    Toggle On
    Toggle Off
  • Front First
    Toggle On
    Toggle Off
  • Both Sides
    Toggle On
    Toggle Off
  • Read
    Toggle On
    Toggle Off
Reading...
Front

How to study your flashcards.

Right/Left arrow keys: Navigate between flashcards.right arrow keyleft arrow key

Up/Down arrow keys: Flip the card between the front and back.down keyup key

H key: Show hint (3rd side).h key

A key: Read text to speech.a key

image

Play button

image

Play button

image

Progress

1/33

Click to flip

33 Cards in this Set

  • Front
  • Back
Chlamydia Trachomatis
biology and transmission
obligate intracellular parasite
grows in columnar epithilium
most often sexually transmission
Chlamydia Trachomatis
life span
6-14 incubation
can live indefinitely
Chlamydia Trachomatis
clinical manifestations females
80% asymptomatic
dysuria
vaginal DC
nonspecific abdominal pain
dyspareunia
post-coital bleeding
cervicitis
uretrhitis
PID
Bartholin's cyst
Protocolitis
Chlamydia Trachomatis
clinical manifestations males
25% asymptomatic
scant clear or cloudy DC
dysuria
urethral pruritis
urethritis
Epidymitis
Protocolitis
Chlamydia Trachomatis
complications
PID
Salgingits/Endometritis
Infertility
Ectopic pregnancy
Fitz-Hugh-Curtis Syndrome (perihepatitis associated with PID)
protocolitis (rectal pain)
Reiter's syndrome (urethritis, arthritis, conjunctivitis)
Chlamydia Trachomatis in pregnancy
^risk of PROM and prematurity
^low birth weight
risk of pp endometritis
risk of infection in exposed infant (conjunctivitis or pneumonitis)
Chlamydia Trachomatis
diagnositis testing
Nucleic Acid Amplification testing
80-95% sensitivity >98% specificity
Tissue culture: >99% specifity, 50-85% sensitivity b/c inadequate specimin
gram stain for WBCs
Chlamydia Trachomatis
treatment in NON PREGNANT WOMEN
first line
Azithromycin 1gm POx1 or Doxycline 100mg PO BID x7days
Chlamydia Trachomatis
treatment in PREGNANT WOMEN
first line
Azithromycin 1gm POx1
Amoxicilin 500mg PO TIDx7days
Chlamydia Trachomatis
Patient Education
Acquisition, implications
safe sex,
no sexual intercourse for 7 days after both partners are treatment
Chlamydia Trachomatis
follow up
Test all sexual contacts within 60days or last partner if >60days
TOC not recommended except pregnant women (3-4 weeks)
TOC for pt's treated with erythromycin
ALL WOMEN need retesting in 3 months (b/c high reinfection rate)
Gonorrhea "the Clap"
pathology
Neisseria gonorrhea
gram negative intracellular diplococcus ("GNIC diplo")
Gonorrhea
life cycle
incubation 2-8 days
transmission by sexual contact
infection limited to mucosal surfaces-columnar epithilium
dervic, urethra, rectum pharynx, conjunctiva
Gonorrhea
clinical manifestations
females
cervicitis
urethritis
salpingitis/endmetriis
Bartholin's Gland cyst
Proctocolitis
Disseminated GC (associated with asymtomatic,infection of pharynx, urethra, or cervix)
Gonorrhea in pregnancy
controversial
may ^risk of PROM/prematurity
may ^risk of chorio
^of pp endometritis
Gonorrhea diagnostic testing
gram stain can be used for presumptive testing in males,
only for women if see intracellular diplo.
NAAT less sensitive in urine than cervical samples (women)
Gonorrhea
treatment non-pregnant women and pregnant
first line
ceftriazone 125 IMx1
cefixime,me 400mg POx1
cefpodoxime 400mg POx1
+presumptively treat for CT unless NAAT culture negative
Gonorrhea
follow up
treat all partners within 60days
no TOC of cure needed unless pregnant
re-test ALL WOMEN in 3 mo.
Trichomonas
pathogenic protozoan
flagellated parasite of GU tract
Trichomonas
transmission and incubation
usually sexually,
fomite transmission possible
incubation period 5-28days
Trichomonas vaginalis
in Pregnancy
^PROM+premature delivery
exposed infants may develop vaginal d/c
Trichomonas vaginalis
clinical manifestations
malodorous DC
yellow, whitish yello, green FROTHY
urethritis,dysuria, frequency, urethral DC
vaginitis
may be asymptomatic
Strawberry cervix
Trichomonas vaginalis
Diagnosis
motile trichomonads on NaCl wetmount
+PMNs
KOH may have amine odor
pH elevated >4.5
culture-Diamond's medium
DNA probes
ADD: GC/CT/HIV/RPR
Trichomonas vaginalis
Treatment
Metronidazole 2gm PO x1 (ok pregnancy)
or Tinidazole 2gm PO x1
Trichomonas vaginalis
Patient education
no Etoh 24hrs after metronidazole or 72hrs after tinidazole
avoid sex until both partners complete treatment
Herpes Simplex Virus
transmission
humans are sole reservoir
readily inactivated by room temp and drying
transmitted via mucosal contact
incubation 1-45days, 4 day average
Primary Herpes
Clinical manifestations
systemic involvement (fever, HA, malaise, myalgia)
tender inginal lymphadenopathy;
viarlsehding during primary episode lasts 11-14days
Non-primary first episode herpes
initial outbreak in person with antibodies to either HSV1 or HSV2
-only way to distinguish a non-primary first oubreak is by seologic testing
Recurrent Herpes outbreak
usually 4x/year, then decrease
average 5-10 days,
viral shedding average 4 days
TRIGGERS: stress, menses, illness, trauma, sunlight, sexual activity (friction)
Asymptomatic Herpes
viral shedding 2-27% of time
is usually labia, not cervical
HSV diagnostic testing
tissue culture gold standard,
best samplef from intact vesicle within 48 hrs after symptoms (up to 40% falsely negative)
Additional: RPR and HIV
HSV treatment goal
decrease symptoms,
shoren duration of outbreak,
suppress recurrent outbreak,decrease asymptomatic shedding
Acyclovir 400mg TID 7-10days
HSV suppression
safe up to 6 years
offer if >or=6 outbreaks per year,
benefitis usually evident after 3-6mo
Acycolvir 400mg BID
reduces outbreaks 70-80%