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18 Cards in this Set
- Front
- Back
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Calculating Renal Clearance
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Clearance= UxV/Px
Units are mL/min |
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GFR Calculation
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Clearance of Creatinine or Inulin
Clearance= UxV/Px |
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Calculating Renal Plasma Flow
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Clearance of PAH
Clearance= UxV/Px |
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Calculating Renal Blood Flow
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RBF= RPF/(1-Hct)
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Calculating Free Water Clearance
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Urine Flow Rate= Clearance H20 + Clearance of Osm
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High Anion Gap Metabolic Acidosis
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Methanol (Formic Acid)
Uremia Diabetic Ketoacidosis Paraldehyde or Phenformin Iron tablets or INH Lactic Acidosis Ethylene Glycol Salicylates (Salicylic acid) |
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Calculating Respiratory Compensation to Metabolic Acidosis
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PCO2= 1.5 (HCO3) + 8
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Acute Post-Strep GN
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Glomeruli enlarged and hypercellular due to neutrophils
IgG/C3 Subepithelial humps Grandular, Lumpy Bumpy IF 2-3 weeks after throat or skin infect. |
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Rapidly Progressive Crescentic GN
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LM and IF show a crescent moon
Wegeners (cANCA)- also URI Goodpastures (antiGBM)- linear IF Microscopic Polyarteritis (pANCA) |
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Diffuse Proliferative GN
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Due to SLE
Subendothelial deposits of IC Wire looping of capillaries Anti-DNA Abs |
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Berger's Disease
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IgA IC in mesangium
2-3 days after URI If systemic symptoms= HSP |
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Alport's Syndrome
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Mutation in Type IV Collagen
Split basement membrane Ocular disorders and deafness present |
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Membranous GN
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MCC of adult nephrotic syndrome
Subepithelial spike and dome ICs Caused by drugs, infection, SLE |
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Minimal Change Disease
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Often post-infectious
Responds well to corticosteroids |
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Amyloidosis
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Congo red stain with apple-green birefringence
Associated with Multiple Myeloma, chronic conditions, TB, RA |
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Diabetic Glomerulonephropathy
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Glycosylation of GBM increases permeability and thickening
Glycosylation of efferent arterioles causes increased GFR *Mesangial damage and wire looping Kimmelstiel- Wilson Nodules |
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Focal Segmental Glomerulosclerosis
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Most common glomerular disease of HIV patients
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Membranoproliferative GN
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Subendothelial ICs and "tramtracking" on EM because of mesangium growing into the GBM
Associated with HBV>HCV |
