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22 Cards in this Set

  • Front
  • Back
What are some common causes of chronic meningitis?
-mycobacteria
-fungi
-lyme disease
-parasites
What are the most common causes of acute meningitis in neonates? list in order of prevalence
1. Group B strep
2. E. coli
3. Listeria meningitides
What are the most common causes of acute meningitis in children >3 months? list in order of prevalence
1. Neisseria meningitides
2. Strep pneumoniae
3. H influenzae
What are the most common causes of acute meningitis in adults (18-50)? list in order of prevalence
1. Strep pneuominiae
2. N. meningitides
3. H. influenzae
What are the most common causes of acute meningitis in the elderly (>50)? list in order of prevalence
1. Strep pneumoniae
2. N. meningitides
3. L. monocytogenes
What are the most common causes of acute meningitis in immunocompromised individuals? list in order of prevalence (3)
1. L. monocytogenes
2. Gram negative bacilli
3. S. pneumoniae
What are some causes of aseptic meningitis? (4)
-enteroviruses
-HSV
-parasites
-fungi
What are some common signs and symptoms of bacterial meningitis? List as many as you can
-headache
-fever
-n/v
-still, painful neck
-alteration in mental status
-nuchal rigidity
-maculopapular rash with petechiae
cranial nerve palsies
-kernig's and bradzinski's
What are the characteristic CSF findings for bacterial meningitis?
hint: glucose, protein, WBC etc...
1. Elevated WBC (incr. PMNs)
2. Low Glucose
3. High protein
4. Gram stain positive in 75-80%
What are the characteristic CSF findings for asceptic meningitis?
1. Elevated WBC (lymphocytes)
2. Protein is normal or slightly elevated
3. Glucose normal

NB: CSF may be completely normal
What are the steps in mngt of bacterial meningitis?
1. CT if focal neuro signs
2. Perform LP and send CSF for cell count, chemistry, gram stain and culture
3. Obtain blood Cx before Abx given
4. Administer empiric abx
5. Consider steroids (controversial)
What is the empiric Abx treatment for infants with suspected bacterial meningitis?
Cefotaxime + ampicillin + vancomycin

(aminoglycoside if <4 wks)
What is the empiric Abx treatment for 3 yrs to 50yrs with suspected bacterial meningitis?
Ceftriaxone or cefotaxime + vancomycin
What is the empiric Abx treatment for > 50yrs with suspected bacterial meningitis?
Ceftriaxone or cefotaxime + ampicillin + vancomycin
What is the empiric Abx treatment for immunocompromised individuals with suspected bacterial meningitis?
Ceftazidime + ampicillin + vancomycin
For all close contacts of pts with meningococcus, what prophy should be used? (2 options)
1. Rifampin
2. 1 dose of IM Ceftriaxone
Common causes of encephalitis?
Usually viral in origin
-Herpes (HSV-1)
-Arbovirus
-Enterovirus
What is the most specific and sensitive test for diagnosing viral encephalitides?
CSF PCR
What is the characteristic finding on MRI of HSV encephalitis?
Increased areas of T2 signal in the frontotemporal localization
What would the EEG show with HSV-1 encephalitis?
unilateral or bilateral temporal lobe discharges
Treatment of HSV encephalitis? CMV encephalitis?
1. HSV encephalitis --> acyclovir for 2-3 wks
2. CMV encephalitis --> ganciclovir
What are the most common non-bacterial causes of brain abscesses?
AIDS:
- Toxoplasma gondii
- fungi

Neutropenic:
- Candida spp
- Aspergillus spp
- Zygomycosis