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9 Cards in this Set
- Front
- Back
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S/E retinitis pigmentosa
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Thioridazine
Typical Antipsychotic |
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S/E corneal deposits
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Chlorpromazine
Typical Antipsychotic |
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Typical Antipsychotics MOA
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MOA- block DA---> increase cAMP
-mainly work for positive signs of SCTZ S/E- gynecomastia, dystonia and tardative dyskinesia -block of MUSC---> dry mouth, constipation -block alpha-1----> hypotension -block H1---> sedation |
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S/E hypotension via Typical Antipsychotics mediated by
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blocking alpha-1 rec
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S/E dry mouth and constipation mediated by typical anti-psychotics by
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antimuscarinic
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name TYPICAL antipsychotics
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-Haloperidol
-Trifluoperazine -Fluphenazine -Thioridazine---> retinitis pigmentosum -Chlorpromazine----> corneal deposits |
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main S/E Haloperidol
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EPS----> tardative dyskinesia, dystonia
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Neuroepileptic malignant syndrome
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-mainly from TYPICAL antipsychotics
-rigid, MYOGLOBINURIA, hyperpyrexia, autonomic instability Tx: dantrolene (block ryanodine rec. from releasing Ca2+), DA agonists |
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Tardative dyskinesia
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EPS assoc. w/ Typical AP
-mainly mouth movements |
