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24 Cards in this Set

  • Front
  • Back
topical Ampho B
Nystatin

MOA: bind ergosterol
AmphoB MOA
binds ergosterol----> causes pore

S/E- arrythmias, fever/ chills, anemia, phlebitis, nephrotoxic
Nystain uses
-oral thrush

-diaper rash

-
Azoles MOA
(-) synthesis of ergosterol
Fluocytosine MOA
(-) RNA/ DNA biosynthesis

-converts to 5'-fluorouracil
Capsofungin MOA
(-) synthesis of beta-glucan----> no cell wall synthesis
Micafungin MOA
Copyright (c) USMLEWorld, LLC., Please do not save, print, cut, copy or paste anything while a test is active.
Terbinafine MOA
(-) squalene epoxidase

Tx; dermatophytoses
Griseofulvin MOA
(-) microtubule formation
(-) squalene eopxidase(anti-fungal)
Terbinafine

Tx: dermatophytoses

S/E- high LFT, visual disturbances
(-) microtubule formation in fungal cells
Griseofulvin

***deposits in keratin-tissues****

S/E- teratogenic, carcinogenic, increase warfarin metabolism
testosterone inhibition S/E w/ fungal Tx
Azoles--> (-) ergosterol synthesis


also causes liver dysfxn
DOC thrush
Nystatin---> binds ergosterol
DOC prevention of vertical HIV
Zidovudine

MOA- NRTI (nucleoside RT inhibitor)
Zidovudine
NRTI

DOC prenatal HIV

S/E- BM supression, lactic acidosis, peripheral neuropathy, ANEMIA
NRTIs
-Zidovudine

-Tenofovir

-Abacavir

-Lamivudine

-Didanosine

-Stavidune
Tenofovir
NRTI----> does not require activation

S/E- BM supression, peripheral neuropathy, lactic acidosis
NRTI which does not require activation
Tenofovir

NRTIs requiring activation: Zidovudine, Abacavir, Didanosine, Stavudine, Lamivudine
Lamivudine
NRTI- requires conversion

S/E- peripheral neuropathy, lactic acidosis, BM supression
Stavudine
Copyright (c) USMLEWorld, LLC., Please do not save, print, cut, copy or paste anything while a test is active.
HIV fusion inhibitor
Enfuvirtide (only one)

blocks gp41
Raltegravir
(-) HIV integrase

S/E- hypercholesterolemia
HIV integrase inhibitor
Raltegravie

S/E Hypercholesterolemia
protease inhibitor names
end in "-NAVIR"

LopiNAVIR
AtazaNAVIR
DaruNAVIR
FosampreNAVIR
(and others)