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20 Cards in this Set
- Front
- Back
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181. What are the“B” symptoms of lymphoma?
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a. Fever
b. weight loss c. night sweats |
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182. What is the significance of “B” symptoms of lymphoma?
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a. Implies more widespread disease.
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183. Presentation of lymphoma?
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a. Enlarged lymph nodes, most commonly in the cervical area.
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184. Presentation of Hodgkin's disease (HD)?
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a. Spreads centrifugally away from the center, starting at the neck.
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185. Presentation of non-Hodgkin's lymphoma (NHL)?
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a. More often presents as widespread disease.
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186. What is the best initial tests for both Hodgkin's disease and non-Hodgkin's lymphoma?
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a. Excisional lymph node biopsy.
b. The most common wrong answer is needle biopsy (needle biopsy is useful for infections such as tuberculosis but is not sufficient to diagnose lymphoma, because the visual appearance of lymphoma cells is normal; they are grossly abnormal like acute leukemic blasts. |
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187. What is the main difference between HD and NHL?
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a. HD has Reed-Sternberg cells.
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188. For the next test for lymphoma after the excisional biopsy shows abnormal architecture of the cells?
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a. Further tests determine the stage of the lymphoma; staging is critical to determine therapy.
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189. Stage 1 lymphoma?
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a. Single lymph node group
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190. stage 2 lymphoma?
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a. Two lymph node groups on one side of the diaphragm
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191. Stage 3 lymphoma?
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a. Lymph node involvement on both sides of the diaphragm.
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192. Stage IV lymphoma?
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a. Widespread disease
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193. what percent of Hodgkin's disease presents in stage I and II?
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a. 80 to 90%.
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194. what percent of non-Hodgkin's lymphoma presents in stages III and IV?
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a. 80 to 90%.
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195. what tests are involved in the staging of lymphoma?
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a. CXR
b. CT scans (with contrast): chest, abdomen, pelvis and head. c. Bone marrow biopsy |
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196. treatment of lymphoma localized disease without “B” symptoms?
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a. Treated predominately with radiation.
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197. Treatment of stages three and four?
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a. Chemotherapy
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198. what is the chemotherapy regimen for HD?
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a. A BVD
1. Adriamycin [doxorubicin] 2. bleomycin 3. vinblastine 4. Dacarbazine |
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199. what is the chemotherapy regimen for NHL?
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a. CHOP
1. cyclophosphamide 2. hydroxyadriamycin 3. Oncovin [Vincristine] 4. prednisone 5. also, test for anti-CD 20 antigen; if present, add rituximab, which adds efficacy to CHOP. |
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200. Presentation of Von Willebrand's Disease (VWD)?
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a. Bleeding from platelet dysfunction- superficial bleeding from the skin and mucosal surfaces, such as the gingiva, gums and vagina.
b. Epistaxis is consistent with platelet dysfunction. c. The question may say bleeding is worse with the use of aspirin. |
