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46 Cards in this Set
- Front
- Back
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drugs that cause diabetes insipidus
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lithium
medroxyflurane demeclocyline |
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halothana causes
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liver necrosis
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vincristine causes
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peripheral neuropathy
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amiodarone causes
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peripheral neuropathy
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phenytoin causes
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foalte def
teratogen hirsutism |
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thioridazine (typical antipsychotic) causes
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retinal deposits
cardiac tox |
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heparin causes
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thrombocytopenia
thrombosis |
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clofibrate SE
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increases GI neoplasms
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tetracycline SE
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photosensitivity
teeth staining in children |
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quinolones cause
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cartilage damage
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quinine causes
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cinchonism (tinnitus, vertigo)
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morphine causes
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sphincter of ODDI spasms
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chloramphenicol
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aplastic anemia
gray baby syndrome |
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causes of SIADH
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chlorpropamide
oxytocin opirates |
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causes of malignant hyperthermia
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succinylcholine
halogen anesthesia |
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zidovudine SE
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bone marrow suppression
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digitalis SE
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GI disorders
vision changes arrhythmias acetazolamide -metabolic acidosis |
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wargarin SE
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necrosis and teratogen
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statin SE
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liver andm uscle toxicity
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ethambutol SE
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optic neuritis
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metronidazole SE
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disulfiram like reaction w/ alcohol
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Cisplatin SE
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nephorotoxicity
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methyldopa SE
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hemoltic anemia
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SSRI SE
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anxiety, agitation, insomnia
sexual dysfunction |
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SE of beta blockers
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sedation, depression, sexual dysfunction
bradycardia and heart block precipitate asthmatic attacks and mask sx of hypoglycemia avoided or used with caution in asthmatics and COP atenolol and metoprolol or combined, carvedilol is preffered is beta blockers is needed to treat heart disease use in diabetics --must weigh risks and benefits |
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metronidazole SE
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disulfiram like reaction w/ alcohol
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Cisplatin SE
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nephorotoxicity
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methyldopa SE
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hemoltic anemia
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SSRI SE
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anxiety, agitation, insomnia
sexual dysfunction |
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SE of beta blockers
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sedation, depression, sexual dysfunction
bradycardia and heart block precipitate asthmatic attacks and mask sx of hypoglycemia avoided or used with caution in asthmatics and COP atenolol and metoprolol or combined, carvedilol is preffered is beta blockers is needed to treat heart disease use in diabetics --must weigh risks and benefits |
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SE of thiazides
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calcium retention
hyperglycemia hyperuricemia hyperlipidemia hyponatremia metabolic alkalosis hypovolemia watch out for sulfur allergy |
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SE of loops
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hypokalemia
hypovolemia otoxicity calcium excretion metabolic alkalosis |
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MAO inhibitor + meperidine -->
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COMA
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AG + Loop -->
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ototoxicity
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thiazide + lithium -->
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lithium toxicity
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MAO inhibitor + SSRI -->
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serotoning syndrome: hyperthermia, rigidity, myoclonus, autonomic instability
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didanosine SE
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pancreatitis
peripheral neuropathy |
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prophylaxis for neisseria meningitidis
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rifampin
cipro ceftriazone azithromycin |
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3 medications that cause hepatic enzyme induction
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barbiturates
antieplileptics rifampin |
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2 meds that inhibit hepatic enzymes
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erythromycin
ketoconazole |
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aspirin SE
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GI upset and bleeding
renal damage or aggravate gout toxic doses of aspirin can cause tinnitus, vertigo, resp alkalosis, metabolic acidosis, hyperthermia, coma, and death severe overdoses of aspirin can be removed by dialysis |
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SE non-aspirin NSAIDs
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GI upset, bleeding, ulcers
NSAIDs may cause renal damage: interstitial nephritis, ATN, papillary necrosis esp in pts who take them chroniclally and preexisting renal disease phenylbutazone can cause fatal aplastic anemia and agranulocytosis |
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what can reduce GI complications of NSAIDs
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prostaglandin E1 - protect stomach by supplying what NSAIDs take away
cyclooxygenase II inhibitors: avoid problem altogether |
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OD of actaminophen
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liver toxicity and depletion of glutathion
tx acetylcysteine |
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low dose aspirin in MI
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proved to be a benefit in reducing risk of MI in both pts who have previous MI and pts w/ stable or unstable angina
receive aspirin indefinitely aspirin is recommended in all diabetics risk of aspirin prophylaxis may outweight benefits in pts w/ hx of liver dz, kidney dz, peptic ulcer dz, GI bleeding, poorly controlled HTN, bleeding disorder |
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chlorpromazine SE
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jaundice
photosensitivity |
