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96 Cards in this Set
- Front
- Back
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Induce or inhibit P450:
Barbs |
Induce
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Induce or inhibit P450:
Phenytoin |
Induce
(same as carbamazepine) |
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Induce or inhibit P450:
Carbamazepine |
Induce
(same as phenytoin) |
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Induce or inhibit P450:
Rifampin |
Induce
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Induce or inhibit P450:
Quinidine |
induce
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Induce or inhibit P450:
Griseofulvin |
Induce
(contrast ketoconazole) |
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Induce or inhibit P450:
Cimetidine |
Inhibit
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Induce or inhibit P450:
Ketoconazole |
Inhibit
(contrast griseofulvin) |
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Induce or inhibit P450:
INH |
Inhibit
(contrast: rifampin) |
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Induce or inhibit P450:
GRAPEFRUIT |
Inhibit
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Induce or inhibit P450:
Sulfonamides |
Inhibit
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Increase toxicity of WHAT OTHER DRUG:
Quinidine |
Digoxin
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Increase toxicity of WHAT OTHER DRUG:
cimetidine |
Digoxin
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Increase toxicity of WHAT OTHER DRUG:
Amiodarone |
Digoxin
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Increase toxicity of WHAT OTHER DRUG:
CEBs |
Digoxin
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What 3 drugs compete for albumin-binding sites?
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Warfarin
ASA Phenytoin |
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Safe in G6PD?:
ASA |
No -- hemolysis
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Safe in G6PD?:
Ibuprofen |
No
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Safe in G6PD?:
Nitrofurantoin |
No
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Safe in G6PD?:
Chloramphenicol |
No
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S/E: what skin reaction?:
Ethosuximide |
SJS
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S/E: what skin reaction?:
Sulfonamides |
SJS
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What abx: S/E photosensitivity
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Tetracycline
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What antifungal: S/E gynecomastia
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Ketoconazole
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What ANTIDOTE:
Acetaminophen |
NAC
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What ANTIDOTE:
-acid ingestion -alkali ingestion |
EGD (eval stricture)
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What ANTIDOTE:
Organophosphate (anticholinesterase) |
ATROPINE, pralidoxime
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What ANTIDOTE:
Arsenic, mercury, gold |
Succimer, dimercaprol
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What ANTIDOTE:
Beta-blocker O/D |
glucagon
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What ANTIDOTE:
Barbiturates |
urine alkalinize, HD, charcoal
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What ANTIDOTE:
Benzos |
Flumenazil (can precip O/D)
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What ANTIDOTE:
Black widow bite |
Calcium gluconate
Methocarbamol |
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Carbon monoxide O/D: hyperbaric O2 useful?
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YES
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What ANTIDOTE:
Cooper |
Penicillamine
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What ANTIDOTE:
Cyanide |
Amyl nitrate
Sodium nitrate Sodium thiosulfate |
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Txs what O/D?:
Amyl nitrate; sodium thiosulfate |
Cyanide
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What ANTIDOTE:
Digitalis O/D |
Normalize K (avoid giving Ca)
Antidig Fab |
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What ANTIDOTE:
Heparin |
Protamine sulfate
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Txs what O/D?:
Protamine sulfate |
Heparin
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What ANTIDOTE:
INH |
Pyridoxine
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What ANTIDOTE:
Iron |
Defuroxamine
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What ANTIDOTE:
Lead |
Succimer
CaEDTA Dimercaprol |
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What ANTIDOTE:
Methemglobin |
Methylene blue
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Txs what O/D?:
Methylene blue |
Methemglobin
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ASA O/D: should you alkalinize urine?
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YES
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What ANTIDOTE:
TCA O/D |
Sodium bicarbonate (for QRS prolong)
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What ANTIDOTE:
tPA/streptokinase |
Aminocaproic acid
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Txs what O/D?:
Aminocaproic Acid |
tPA/streptokinase
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What drug: S/E:
Ataxia, LIVEDO RETICULARIS |
Amantadine
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What drug: S/E:
Ototoxic, nephrotoxic (ATN) |
Aminoglycosides
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What drug: S/E:
Acute: AV block, hypoT, brady Chronic: Pulm fibrosis, blue skin, hypo/hyperthyroid |
Amiodarone
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AZT: leads to what blood abns?
|
thrombocytopenia
anemia |
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What drug: S/E:
Asthma exacerb, masking of hypogly, AV block |
Beta-blocker
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What BP MEDS? S/E:
periph edema, constipation, cardiac depression |
CEB
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What drug: S/E:
Agranulocytosis, aplastic anemia, liver toxicity |
Carbamazepine
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Carbamazepine: most imp S/E?
|
Agranulocytosis
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What drug: S/E:
Gray baby synd |
Chloramphenicol
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Chloramphenicol: #1 S/E
|
Gray baby synd
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What drug: S/E:
Severe rebound HA & HTN |
Clonidine
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Clondine: most imp S/E
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Severe rebound HA & HTN
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Clozapine: most impt S/E
|
agranulo
(same as carbamazepine) |
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What drug: S/E:
Hemorrhagic cystitis |
Cyclophosphamide
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Cyclophosphamide: most imp S/E?
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Hemorrhagic cystitis
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Doxorubicin: most imp S/E?
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Cardiomyopathy
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What drug: S/E:
Cartilage damage in children; Achilles tendon rupture in adults |
Fluoroquinolones
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Fluoroquinolones: what imp S/E?
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Cartilage damage in child; Achilles tendon in adult
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Furosemide: what lyte abn?
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Hypokalemia
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What drug: S/E:
Ototoxic, hypokalemia, nephritis, gout |
Furosemide
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Gemfibrozil: what S/E?
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Myositis, reversible increase LFTs
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What drug: S/E:
hepatotoxic; MALIGNANT HYPOTHERMIA |
Halothane
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Halothane: what unique S/E
|
malig hypothermia
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What drug: S/E:
HypoK+, hypoNa, hyperuricemia, hypergly, hyperCa |
HCTZ
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Hydralazine: what imp S/E?
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Drug-induced SLE
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Hydroxychloroquine: what imp S/E?
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Retinopathy
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INH: how prevent periph neuropathy?
|
Pyridoxine (B6)
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INH: safe in G6PD?
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No
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MAOI: induces SSRI if combine w/what drug?
|
Meperidine
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What alcohol:
S/E blindness |
Methanol
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What drug: S/E:
Hepatic fibrosis, pneumonitis, anemia |
MTX
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What drug: S/E:
Metallic taste; disulfiram rxn, vestibular dysfxn |
Metronidazole
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Metronidazole: what unique S/E?
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Metallic taste
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What drug: S/E:
Gingival hyperplasia |
Phenytoin
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Phenytoin: what unique S/e?
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Gingival hyperplasia
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What drug: S/E:
1st-dose hypoT |
Prazosin
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Prazosin: what unique S/E?
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1st-dose hypoT
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PTU: what blood abns?
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Agranulocytosis
Aplastic anemia |
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What drug: S/E:
HA, tinnitus, thrombocytopenia, TORSADES |
Quinidine
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Quinidine: what arryth S/E?
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Torsades
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Reserpine: what imp S/E?
|
depression
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Succinylcholine: what lyte abn?
|
Hyperkalemia
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What anesthetic:
S/E malignant hyperthermia |
Succinylcholine
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What drug: S/E:
Tooth discoloration |
Tetracyclines
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What drug: S/E:
Red man synd |
Vancomycin
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Vancomycin: what imp S/E?
|
Red man synd
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Vinblastine: what imp S/E?
|
Severe myelosuppression
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Barbiturate w/d: tx with what med class?
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BENZOS
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