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69 Cards in this Set
- Front
- Back
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Cardiovascular
___ cause coronary vasospasm |
MACET
Methamthetamines Amphetamines CCB (Calcium Channel Blockers) Ergots Triptans |
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Cardiovascular
__ cause cutaneous flushing |
VANC
Vancomycin Adenosine Niacin CCB |
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Cardiovascular
__ cause dilated cardiomyopathy |
DTD
Dactinomycin Trastuzumab Daunorubicin |
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Cardiovascular
__ cause TDP |
Sotalol, Quinidine, Chloroquine, Protease-Is (-navir)
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Hematologic
__ cause agranulocytosis |
Grainy Hail hits
cold closed cars, damaged pretty majorly Cold Colchicine Closed Clozapine Cars Carbamazepine Damaged Dapsone Pretty PTU Majorly Methimazole |
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Hematologic
__ cause aplastic anemia |
Plastics and benzene, chlorine, on North Shore is Pretty Major!
Benzene Benzene and Chlorine Fanning Chloram--phenicol into Northshore is NSAIDS Pretty PTU Major Methimazole |
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Hematologic
__ cause direct Coombs + Hemolytic Anemia |
Methyldopa
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Hematologic
__ cause Gray Baby Syndrome |
Chloramphenicol
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Hematologic
__ cause hemolysis in G6PD pts |
G6PD Hemolysis ISS a Friggin PAINN!
IS Isoniazid, Sulfonamide a Friggin Fava beans P Primaquine A Aspirin I Ibuprofen N Nitrofurantoin N Naphthaline |
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Hematologic
__ cause megaloblastic anemia |
a Blast to have PMS
P Phenytoin M MTX, TMP S Sulfas also from deficiency of B12, Folate, anemia, preg, alcoholics, malabs, malnutrition, etc |
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Hematologic
__ cause throbosis |
OCPs
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To avoid in Pregnancy
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Clearly, SAFe Moms Take Really Good Care
Countless Clarithromycin --- embryotox S sulfonamides ----kernicterus A Aminoglycosides---ototox F fluoroquinolones---cartilage damage M metronidazole---mutagen T tetralycline----teeth discolor, inhib bone growth R ribavirin----teratogen G griseofulvin---teratogen C chloramphenicol---gray baby |
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ok in pregnancy
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I Am Nice and Clazy
Am---oxicillin Ni---trofurantoin C---aphalexin e Cl---indamycin Az---ithromycin E----rythromycin |
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p450 inducers
"the Queen uplifts" |
Queen Quinidine
BarbiE Barbiturates, Ethosuxamide Steels and Smokes St. Johns wort, Smoke (PAH) Phenytoin and Phenitoin Chronically drinks chronic etoh and Refuses Rifampin Greesy, Gluey Griseofulvin, Glucocorticoids Carbs Carbamazepine |
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p450 inhibitors
"the magic racks smashes the enzyme" |
Valery's Valproate
M Macrolines (erythromycin) A Amiodarone (the only antiarrhythmic w/o TDP) G Grapefruit juice I Isoniazid C Cimetidine/Omeprazole R Ritonavir A Acute etoh C Ciprofloxacin/Chloramphenicol K Ketoconazole S sulfonamides |
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Sulfa reactions
rash blood Fever UTI |
Popular FACTSSS
Probenicid Furosemide Celecoxib Thiazide Sulfonamide Sulfasalazine Sulfnylureas |
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Respiratory
__ causes cough |
ACE-I so switch to ARBS (-sartan) to reduce bradykinin
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Respiratory
__ causes pulmonary fibrosis |
hard to BLAB when you have pulmo fibrosis
Bleomycin Amiodarone Busulfan |
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GI
__ cause Acute Cholecystatic Hepatitis |
Macs
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GI
__ cause focal to massive Hep Necrosis |
liver HAVAc
Halothane Acetaminophen Valproate Amanita phalloides |
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GI
__ cause hepatits |
INH
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GI
__ cause pseudomembranous colitis |
any chronic antibiotic use, but commonly in
Clindamycin Ampicillin |
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Repro/Endo
__ cause AdrenoCortical Insuff |
Glucocorticoid w/d suddenly
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Repro/Endo
__ cause gyno |
Some Spironolactone, Steroids
Drugs Digitalis CrEate Cimetidine, Estrogen elevation Awesome Alcohol chronic reduces estrogen metab Knockers Ketoconazole chronic alcohol use reduces estrogen metab so more is elevated in blood exogenous steroids are convered to estrogen by aromatase |
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Repro/Endo
__ cause hotflashes |
Tamoxifen
Clomiphene (SERM) |
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Repro/Endo
__ cause hypothyroid |
thyroid is slammed
Sulfonamide Li Amiodarone |
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Repro/Endo
__ cause hyperglycemia |
Nice Tap
Niacin Tacrolimus Protease Inhibitors |
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Repro/Endo
__ cause pulmonary embolism |
OCP + smoker + >35yo
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MSK
__ cause fat redistribution |
Insulin inj sites
Glucocorticoids Protease-Inhibitors HIV |
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MSK
__ cause gingival hyperplasia |
phenitoin
verapamil |
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MSK
__ cause gout: diretics (2), vitamin, antibiotic (2) |
furosemide
thiazide niacin cyclosporine pyrazinamide |
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MSK
__ cause myopathy |
Fish N CHIPS Give you Myopathy
Fibrates Niacin Colchicine Hydrochloroquine IFN-a Penicillamine Statins Glucocorticoids |
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MSK
__ cause osteoporosis |
Corticosteroids
Heparin |
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MSK
__ cause photosensitivity |
SAT for a Photo
Sulfonamides Amiodarone Tetracycline |
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MSK
__ cause Rash (Stevens Johnson Syndrome) |
Bad Rash after a PEC SLAP
Penicillamine Ethosuxamide Carbamazepine Sulfas Lamotrigine Allopurinol Phenytoin / Phenobarbitol |
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MSK
__ cause lupus like Sx |
Qute CHiM PPP SS
Quinidine Chlorpromazine Hydralazine Methyldopa Procainamide / Phenitoin / Penicillamine Sulfasalazine / Sulfonamides |
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MSK
__ cause tendon rupture (kids) cartilage damage |
Fluoroquinolones
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Renal / GU
__ cause ATN acute tubular necrosis |
aminoglycosides
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Renal / GU
__ cause diabetes incipidus |
Thin Lid
Thiazides because it retains Ca Li Demeclocycline |
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Renal / GU
__ Fanconi Syndrome (PCT can't retain anything) |
expired tetracyclines
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Renal / GU
__ Interstitial Nephritis |
Meth is FUN
Methicillin Furosemide NSAIDS |
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Recal / GU
__ cause hemorrhagic cystitis |
cyclophosphamide so give the antidote mesma to bind the the CP metabolite: acrolein
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Renal / GU
__ cause SIADH |
carbamazepine
cyclophosphamide |
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Neuro
__ cause bad vision |
ethosuxamide
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Neuro
__ cause conchonism |
quinidine
quinine |
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Neuro
__ cause Parkinson Sx |
Mars
Metoclopramide Antipsychotics Reserpine |
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Neuro
__ cause ototoxicity = vertigo, tinnitis b/c CN8 is shot |
AVCF
can't hear so you FACE the VAN Furosemide Aminoglycosides Cisplatin Vancomycin |
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Neuro
__ cause seizures |
CNS and seizure drugs....
Buproprion Clozapine Cilastatin/Imipenem |
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Neuro
__ cause tardive dyskinesia |
Antipsychotics
Metoclopramide (used to prevent post op nausea) |
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Multiorgan
__ cause antiMuscarinic = anti cholinergic Sx = antidumbell... |
red,hot,dry,constip/urine ret,mad, blind, blown pupil
Atropine, Antimuscarinics, Amantadine H1 blockers low potency neuroleptics TCAs Promethazine |
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Multiorgan
__ cause disulfaram rxn |
metronidazole (if combined with alcohol)
sulfonylureas (1st gen, but not used) cephalosporins (some) procarbazine |
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Teratogens from meds
__ cause renal damage |
ACE-I
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Teratogens from meds
__ cause no fingers, etc. |
alkylators
Busulfan CP Nitrosamines |
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Teratogens from meds
__ cause CN3 toxicity |
AG aminoglycosides
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Teratogens from meds
__ cause NTD, craniofacial defets, fingernail HPOplasia, dev delay, IUGR |
Carbamazepine
give patient Folate to compensate |
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Teratogens from meds
__ cause Vagical Clear Cell Carcinoma |
DES diethylstilbesterol
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Teratogens from meds
__ cause NTD |
Folate Antags, Valproate
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Teratogens from meds
__ cause Ebstein's anomaly (atrialized left ventricle) |
Li
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Teratogens from meds
__ cause fetal hydrantoin syndrome: microceph, dysmorphic craniofacial problems, HPOplastic nails and fingers, cardiac problems, Mental Retardation, IUGR |
Phenytoin
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Teratogens from meds
__ cause discolored teeth, permanently |
Tetracycline
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Teratogens from meds
__ cause limb defects = focomelia |
thalidomide
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Teratogens from meds
__ cause bone deformities, fetal hemorrhage, abortion, eye problems |
Warfarin
"don't wage war on baby by giving warfarin" |
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Teratogens from substance abuse
__ cause MCC of birth defects, MR |
alcohol
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Teratogens from substance abuse
__ cause placental abrution, abn fetal dev, fetal addiction |
cocaine will vasoconstrict so reduce bld flow to fetus
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Teratogens from substance abuse
__ cause preterm labor, placenta problems, IUGR, ADHD |
smoking, nicotine, CO
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Teratogens
__ cause congenital goiter, HPOthyroid |
Iodide lack/excess
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Teratogens
__ cause NTD, cong heart defect, caudal regression syndr (from anal atresia to sirenomelia --no legs) |
maternal diabetes
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Teratogens
__ cause spontaneous abortion, birth defects (cleft palate, cardiac problems) |
Vitamin A excess
inhibits neural crest migration inhibits HOX genes |
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Teratogens
__ cause microcephaly, MR |
X-rays
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