Step 1 - Pharm - Endocrine Drugs

Front 1

MOA of orlistat

Back 1

Inhibits pancreatic lipase (thereby altering fat metabolism)

Front 2

Clinical use of orlistat

Back 2

Long-term obesity management

Front 3

Side effect of orlistat

Back 3

Steatorrhea, fat-soluble vitamin deficiencies (A,D,E,K), headache and GI upset

Front 4

MOA of sibutramine

Back 4

Reuptake inhibitor of 5-HT and NE

Front 5

This drug can be used for short-term obesity management, and these drugs for long-term

Back 5

Sibutramine for short-term, sibutramine and orlistat for long-term management

Front 6

This anti-obesity agents has as its side effects hypertension and tachycardia

Back 6

Sibutramine (it is sympathomimetic)

Front 7

MOA of propylthiouracil

Back 7

Inhibits thyroid hormone synthesis, decreases peripheral conversion of T4 to T3

Front 8

MOA of methimazole

Back 8

Inhibits thyroid hormone synthesis

Front 9

This hyperthyroidism medication prevents peripheral conversion of T4 to T3

Back 9

Propylthiouracil

Front 10

These two drugs are used to treat hyperthyroidism

Back 10

Propylthiouracil, methimazole

Front 11

Side effects of these drugs include agranulocytosis (rare), aplastic anemia, and skin rash

Back 11

Propylthiouracil, methimazole

Front 12

This drug is used to treat Turner's syndrome

Back 12

Growth hormone

Front 13

MOA of octreotide

Back 13

Somatostatin analog

Front 14

Clinical uses of octreotide (4)

Back 14

Acromegaly (hyperpituitarism), carcinoid syndrome, gastrinoma, glucagonoma (think of the things that somatostatin inhibits)

Front 15

This drug is given to control uterine hemorrhage, among other things

Back 15

Oxytocin (also given to stimulate labor and milk let-down)
Contracts the uterus

Front 16

This drug is given to treat central DI

Back 16

Desmopressin

Front 17

MOA of desmopression

Back 17

ADH analog

Front 18

MOA of levothyroxine

Back 18

Thyroxine analog

Front 19

MOA of triiodothyronine

Back 19

Thyroxine analog

Front 20

This drug is used to treat myxedema

Back 20

Thryoxine replacements (levothyroxine, triiodothyronine)

Front 21

MOA of triamcinolone

Back 21

Glucocorticoid

Front 22

MOA of glucocorticoids

Back 22

Decrease leukotrienes and prostaglandins by inhibiting phospholipase A2 and COX-2 expression

Front 23

Findings in iatrogenic Cushing's syndrome (caused by glucocorticoids)

Back 23

Buffalo hump, moon facies, truncal obesity, muscle wasting, thin skin (striae), easy bruising, osteoporosis, adrenocortical atrophy, peptic ulcers, diabetes (if chronic)

Front 24

MOA of demeclocycline

Back 24

ADH antagonist (demeclocycle is a tetrocycline)

Front 25

This drug treats SIADH

Back 25

Demeclocycline

Front 26

This drug can cause nephrogenic DI as its side effect

Back 26

Demeclocycline

Front 27

This drug causes photosensitivity, and abnormalities in bone and teeth

Back 27

Demeclocycline