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33 Cards in this Set
- Front
- Back
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PSA
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Prostate specific antigen. Screening for prostate carcinoma, but also elevated in BPH, prostatitis (thus it is not specific, but sensitive; we want screening tests to be sensitive).
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Prostatic acid phosphatase
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Prostate carcinoma
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CEA (Carcinoembryonic Antigen)
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CRC
Pancreatic cancer Gastric carcinoma Breast carcinoma (Very nonspecific. Produced by 70% of colorectal and pancreatic cancer.) |
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Alpha-fetoprotein
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Hepatocellular carcinoma.
Nonseminomatous germ cell tumors of the testes (eg, yolk sac tumor). |
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Beta-hCG
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Hydatidiform moles, choriocarcinomas, gestational trophoblastic tumors ("H.C.G.")
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CA-125
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Ovarian cancer, malignant epithelial tumors
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S-100
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Melanoma
Neural tumors Astrocytomas (from neurectoderm; note that it is not seen in neuroblastoma, which is from neural crest) |
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Alkaline phosphatase
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Metastases to bone; obstructive biliary disease; Paget's disease of bone
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Bombesin
(aka GRP; stimulates gastrin release from G cells of antrum) |
Neuroblastoma, small cell lung cancer, gastric cancer
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TRAP (Tartrate-resistant acid phosphatase)
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Hairy cell leukemia
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Laminated, concentric calcific spherules are seen in these cancers
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Papillary adenocarcinoma of the thyroid; serous papillary cystadenocarcinoma of the ovary; meningioma; malignant mesothelioma (seen in asbestosis)
"P.saM.M.O.ma: Papillary, Meningioma, Mesothelioma, Ovary |
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CA-19-9
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Pancreatic adenocarcinoma
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Colorectal cancer
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CEA
("a sea of shit") |
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Pancreatic cancer
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CEA, CA-19-9
(19-9 is more specific) |
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Gastric carcinoma
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CEA, bombesin
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Breast carcinoma
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CA 15-3
(and CEA) |
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Hepatocellular carcinoma
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alpha-fetoprotein
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Yolk sac tumor
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alpha-fetoprotein
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Hydatidiform moles
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beta-HCG
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Choriocarcinoma
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beta-HCG
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Gestational trophoblastic tumors
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beta-HCG
(think of placenta--trophoblasts) |
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Ovarian cancer
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CA-125
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Malignant epithelial tumors
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CA-125
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Melanoma
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S-100
(think of its origin from neuroectoderm) |
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Neural tumors
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S-100
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Astrocytoma
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S-100
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Bone metastasis
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Alkaline phosphatase
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Obstructive biliary tract
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Alkaline phosphatase
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Paget's disease of bone
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Alkaline phosphatase
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Neuroblastoma
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Bombesin
(remember these are from blast cells, not necessarily neural cells; eg Bombesin, not S-100) |
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Small cell lung cancer
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Bombesin
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Hairy cell leukemia
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TRAP stain
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CA 15-3
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Breast carcinoma
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