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134 Cards in this Set
- Front
- Back
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Actinic (solar) keratosis
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Precursor to squamous cell carcinoma, treat with topical 5-FU
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Acute gastric ulcer associated with CNS injury
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Cushing's ulcer (increased ICP stimulates vagal gastric secretion)
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Acute gastric ulcer associated with severe burns
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Curling's ulcer (greatly reduced plasma volume results in sloughing of gastric mucosa)
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Alternating areas of transmural inflammation and normal colon
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Skip lesions (Crohn's disease)
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Aneurysm, dissectiong
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Hypertension (also Marfan's)
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Aortic aneurysm, abdominal and descending aorta
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Atherosclerosis (abdominal aorta first place to typically show atherosclerosis, smoking greatly increases risk)
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Aortic aneurysm, ascending
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Marfan's syndrome (idiopathic cystic medial degeneration)
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Atrophy of mammillary bodies
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Wernicke's encephalopathy (thiamine deficiency causing ataxia, ophthalmoplegia, and confusion)
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Autosplenectomy (fibrosis and shrinkage)
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Sickle cell anemia (HbSS)
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Bacteria associated with gastritis, peptic ulcer disease, and stomach cancer
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H. pylori
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Bacterial meningitis (adults and elderly)
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Neisseria meningitidis
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Bacterial meningitis (newborns and kids)
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Group B streptococcus (newborns), S. pneumoniae/Neisseria meningitidis (kids)
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Benign melanocytic nevus
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Spitz nevus (most common in first two decades)
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Bleeding disorder with GpIb deficiency
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Bernard-Soulier disease (defect in platelet adhesion to von Willebrand's factor)
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Brain tumor (adults)
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Supratentorial: mets>astrocytoma (including glioblastoma multiforme)>meningioma>schwannoma
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Brain tumor (kids)
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Infratentorial: medulloblastoma (cerebellum) or Supratentorial: craniopharyngioma (cerebelum)
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Breast cancer
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Infiltrating ductal carcinoma (in the United States, 1 in 9 women will develop breast cancer)
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Breast mass
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1. Fibrocystic change
2. Carcinoma (in postmenopausal women) |
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Breast tumor (benign)
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Fibroadenoma
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Cardiac 1` tumor (kids)
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Rhabdomyoma, often seen in tuberous sclerosis
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Cardiac manifestation of lupus
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Libman-Sacks endocarditis (nonbacterial, affecting both sides of mitral valve)
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Cardiac tumor (adults)
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1. Metastasis
2. 1` Myxoma (4:1 left to right atrium; "ball and valve" effect - syncopic episodes) |
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Cerebellar tonsillar herniation
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Chiari malformation (often presents with progressive hydrocephalus and syringomyelia)
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Chronic arrhythmia
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Atrial fibrillation (associated with high risk of emboli)
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Chronic atrophic gastritis (autoimmune)
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Predisposition to gastric carcinoma (can also cause pernicious anemia from destruction of parietal cells -> intrinsic factor)
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Clear cell adenocarcinoma of the vagina
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DES exposure in utero
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Compresion fracture
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Osteoporosis (type 1: postmenopausal woman; type 2: elderly man or woman)
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Congenital adrenal hyperplasia, hypotension
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21-hydroxylase deficiency
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Congenital cardiac anomaly
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VSD
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Congenital conjugated hyperbilirubinemia (black liver)
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Dubin-Johnson syndrome (inability of hepatocytes to secrete conjugated bilirubin into bile)
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Constrictive pericarditis
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Tuberculosis (developing world); systemic lupus erythematosus (developed world)
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Coronary artery involved in thrombosis
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LAD>RCA>LCA
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Cretinism
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Iodine deficit/hypothyroidism
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Cushing's syndrome
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1. Corticosteroid therapy
2. Excess ACTH secretion by pituitary 3. Small cell lung cancer |
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Cyanosis (early; less common)
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Tetrology of Fallot, transposition of great vessels, truncus arteriosis
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Cyanosis (late; more common)
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VSD, ASD, PDA
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Death in CML
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Blast crisis
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Death in SLE
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lupus nephropathy
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Dementia
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1. Alzheimer's disease
2. Multiple infarcts |
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Deymyelinating disease in young women
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Multiple sclerosis
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DIC
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Gram-negative sepsis, obstetric complications, cancer, burns, trauma
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Dietary deficit
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Iron
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Diverticulum in pharynx
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Zenker's diverticulum (diagnosed by barium swallow)
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Ejection click
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Aortic/pulmonary stenosis
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Esophageal cancer
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Squamous cell carcinoma (worldwide); adenocarcinoma (US)
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Food poisoning (exotoxin mediated)
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S. aureus. B. cereus
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Glomerulonephritis (adults)
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Berger's disease (IgA nephropathy)
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Gynecologic malignancy
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Endometrial carcinoma (most common in US); cervical carcinoma (most common worldwide)
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Heart murmor, congenital
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Mitral valve prolapse
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Heart valve in bacterial endocarditis
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Mitral (rheumatic fever), tricuspid (IV drug abuse), aortic (2nd affected in rheumatic fever)
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Helminth infection (US)
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1. Enterobius vermicularis
2. Ascaris lumbricoides |
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Hematoma - epidural
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Rupture of middle meningeal artery (trauma; lentiform or lens shaped)
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Hematoma - subdural
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Rupture of bridging veins (crescent shaped)
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Hemochromatosis
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Multiple blood transfusion or hereditary HFE mutation (can result in CHF, "bronze diabetes," and increased risk for hepatocellular carcinoma)
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Hepatocellular carcinoma
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Cirrhotic liver (associated with hepatitis B and C)
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Hereditary bleeding disorder
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von Willibrand's disease
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Hereditary harmless jaundice
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Gilbert's syndrome (benign congenital unconjugated hyperbilirubinemia)
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HLA-B27
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Ankylosing spondylitits, Reiter's syndrome, ulcerative colitis, psoriasis
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HLA- DR3 or -DR4
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Diabetes mellitus type 1, rheumatoid arthritis, SLE
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Holosystolic murmor
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VSD, tricuspid regurgitation, mitral regurgitation
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Hypercoagulability, endothelial damage, blood stasis
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Virchow's triad(results in venous thrombosis)
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Hypertension, 2`
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Renal disease
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Hypoparathyroidism
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Accidental excision during thyroidectomy
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Hypopituitarism
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Pituitary adenoma (usually benign tumor)
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Infection 2` to blood transfussion
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Hepatitis C
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Infections in chronic granulomatous disease
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Staphylococcus aureus, E. coli, Aspergillus (catalase positive organisms)
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Kidney stones
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1. Calcium = radiopaque
2. Struvite (ammonium) = radiopaque (formed by urease-positive organisms such as Proteus vulgaris or Staphylococcus) 3. Uric acid = radiolucent |
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Late cyanotic shunt (uncorreted L->R becomes R->L)
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Eisenmenger's syndrome (caused by ASD, VSD, PDA; results in pulmonary hypertension/polycythemia) also known as cor pulmonale
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Liver dsease
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Alcoholic cirrhosis
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Lysosomal storage diease
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Gaucher's disease
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Male cancer
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prostatic carcinoma
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Malignancy associated with noninfections fever
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Hodgkin's lymphoma
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Malignant skin tumor
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Basal cell carcinoma (rarely metastasizes)
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Mental retardation
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1. Down syndrome
2. Fragile X syndrome |
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Metastases to bone
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Breast, lung, thyroid, testes, prostate, kidney
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Metastases to brain
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Lung, breast, skin (melanoma), kidney (renal cell carcinoma), GI tract tumors
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Metasteses to liver
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Colon, gastric, pancreatic, breast, and lung carcinomas
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Mitochondrial inheritance
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Disease occurs in both males and females, inherited through females only
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Mitral valve stenosis
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Rheumatic heart disease
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Mixed (UMN and LMN) motor neuron disease
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ALS
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Myocarditis
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Coxackie B
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Neoplasm (kids)
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1. ALL
2. Cerebellar meduloblastoma |
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Nephrotic syndrome (adults)
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Focal segmental glomerulosclerosis
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Nephrotic syndrome (kids)
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Minimal change disease (associated with infections/vaccinations; treat with corticosteroids)
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Neuron migration failure
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Kallmann syndrome
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Nosocomial pneumonia
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Klebsiella, E. coli, Pseudomonas aeruginosa
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Obstruction of the male urinary tract
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BPH
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Opening snap
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Mitral stenosis
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Opportunistic infection in AIDS
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Pneumocystis jiroveci (formerly carinnii) pneumonia
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Osteomyelitis
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S. aureus
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Osteomyelitis in sickle cell disease
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Salmonella
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Osteomyelitis in IV drug use
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Pseudomonas, S. aureus
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Ovarian metastasis from gastric carcinoma or breast cancer
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Krukenberg tumor (mucin-secreting signet-ring cells)
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Ovarian tumor (benign, bilateral)
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serous cystadenoma
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Ovarian tumor (malignant)
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Serous cystadenocarcinoma
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Pancreatitis (acute)
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Gallstones, alcohol
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Pancreatitis (chronic)
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Alcohol (adults), cystic fibrosis (kids)
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Patient with ALL/CLL/AML/CML
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ALL; child, CLL: adult >60, AML: adult ~60, CML: adult 30-60
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Pelvic inflammatory disease
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Neisseria gonorrhoeae (monoarticular arthritis)
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Philadelphia chromosome t(9,22) (bcr-abl)
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CML (may sometimes be associated with ALL/AML)
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Pituitary tumor
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1. Prolactinoma
2. Somatotropic "acidophilic" adenoma |
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Primary amenorrhea
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Turner Syndrome (45XO)
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Primary bone tumor (adults)
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Multiple myeloma
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Primary hyperaldosteronism
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Adenoma of the adrenal cortex
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Primary hyperparathyroidism
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1. Adenomas
2. Hyperplasia 3. Carcinoma |
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Primary liver cancer
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Hepatocellular carcinoma (chronic hepatitis, cirrhosis, hemochromatosis, alpha-1-antitrypsin)
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Pulmonary hypertension
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COPD
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Recurrent inflammation/thrombosis of small/medium vessels in extremities
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Buerger's disease (strongly associated with tobacco)
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Renal tumor
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Renal cell carcinoma: associated with Hippel-Lindau and adult polycystic kidney disease; paraneoplastic syndromes (EPO, renin, PTH, ACTH)
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Right heart failure due to pulmonary cause
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Cor pulmonale
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S3 (protodiastolic gallop)
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Increased ventricular filling (L->R shunt, mitral regurgitation, LV failure [CHF])
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S4 (presystolic gallop)
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Stiff/hypertrophic ventricle (aortic stenosis, restrictive cardiomyopathy)
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Secondary hyperparathyroidism
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Hypocalcemia of chronic kidney disease
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Sexually transmitted disease
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Chlamydia (usually coinfected with gonorrhea)
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SIADH
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Small cell carcinoma of the lung
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Site of diverticula
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Sigmoid colon
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Site of atherosclerosis
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Abdominal aorta>coronary>popliteal>carotid
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Stomach cancer
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Adenocarcinoma
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Stomach ulceration and high gastrin levels
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Zollinger-Ellison syndrome (gastrinoma of duodenum or pancreas)
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t(14,18)
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Follicular lymphomas (bcl-2 activation)
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t(8,14)
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Burkitt's lymphoma (c-myc activation)
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t(9,22)
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Philadelphia chromosome, CML (bcr-abl fusion)
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Temporal arteritis
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Risk of ipsilateral blindness due to thrombosis of ophthalmic artery; polymyalgia rheumatic
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Testicular tumor
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Seminoma
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Thyroid cancer
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Papillary Carcinoma>Follicular Carcinoma>Medularry Carcinoma> Adenocarcinoma
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Tumor in women
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Leiomyoma (estrogen dependent, not precancerous)
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Tumor of infancy
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Hemangioma (usually regresses spontaneously by childhood)
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Tumor of the adrenal medulla (adults)
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pheochromocytoma (usually benign)
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Tumor of adrenal medulla (kids)
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Neuroblastoma (malignant)
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Type of Hodgkin's
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Nodular sclerosis (vs. mixed cellularity, lymphocytic predominance, lymphocytic depletion)
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Type of non-Hodgkin's
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Diffuse large cell
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UTI
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E. coli, Staphylococcus saprophyticus (young women - "honeymoon cystitis")
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Viral encephalitis affecting temporal lobe
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HSV-1
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Vitamin deficiency (US)
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Folic acid (pregnant women are at high risk; body stores only 3-4 months supply; prevents neural tube defects)
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