Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
19 Cards in this Set
- Front
- Back
|
What are the adverse effects of Hydrochlorothiazide?
|
hypokalemia, hypercalcemia, hyperglycemia
|
|
|
What are the adverse effects of Loop diuretics?
|
hypotension, ototoxicity, potassium wasting
|
|
|
List the Sympathoplegic drugs
|
- Clonidine
- Methyldopa - B-blockers - Hexamethonium - Reserpine - Prazosin - Guanethidine |
|
|
What's the main adverse effect of Methyldopa?
|
Positive Coombs' test
|
|
|
What are the advers effects of Prazosin?
|
- 1st dose orthostatic hypotension
- dizziness - headache |
|
|
Beta blockers: Adverse Effects
|
- impotence
- cardiovascular effects - CNS effects |
|
|
List the vasodilators
|
- Diazoxide
- Minoxidil - Hydralazine - Nifedipine, Verapamil - Nitroprusside |
|
|
Hydralazine: Adverse Effects
|
- Lupus-like syndrome
- reflex tachycardia |
|
|
Verapamil: Adverse Effects
|
- flushing
- constipation - AV block |
|
|
Nitroprusside: Adverse Effects
|
- cyanide toxicity (CN release)
|
|
|
List the ACE Inhibitors
|
- Captopril
- Enalapril - Fosinopril |
|
|
ACE Inhibitor: Adverse Effects
|
- hyperkalemia
- cough - angioedema - fetal renal damage |
|
|
List the Angiotensin II Receptor Inhibitors
|
Losartan
|
|
|
Losartan: Adverse Effects
|
fetal renal toxicity
|
|
|
What's the MOA of Hydralazine?
|
- Increases cGMP --> smooth muscle relaxation
- Vasodilates arterioles > veins |
|
|
What drugs are 1st-line therapy for HTN in pregnancy?
|
Hydralazine and Methyldopa
|
|
|
List the Calcium Channel Blockers
|
- Nifedipine
- Verapamil - Diltiazem |
|
|
What's the mechanism of Calcium Channel Blockers?
|
Block voltage-dependent L-type calcium channels of cardiac smooth muscle --> reduced muscle contractility
|
|
|
Clinical uses of Calcium Channel Blockers
|
- Prinzmetal's angina
- Raynaud's |
