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6 Cards in this Set
- Front
- Back
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STEM Cells arise from - Extraction of stem cells = |
Arise from- mesoderm Extraction=invasive procedure |
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umbilical cord blood STEM cells source of: low: easy to: costly to: |
source of: multipotent hematopoietic stem cells low: immunogenicity easy to: collect costly to: store |
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Differentiation Potential 1. Totipotent= 2. Pluripotent= 3.Multipotent= 4. Unipotent= 5.Terminally Differentiated= |
1. totipotent= can become anything, including embryo and placenta e.g. Zygote (1 cell embr.) 2. pluripotent=can become any embryonic tissue but NOT placenta e.g. blastocyst, embryonic stem cells 3. multipotent=can become multiple tissues within a family e.g. adult stem cells, cord blood, and marrow 4. unipotent=diff. stem cells, only one type but can self-renew e.g. skin cells 5. Terminally Diff=cannot self-renew, e.g. red blood cells |
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Plasticity= More differentiated= Glia= astrocytes= blastocyts= blastocoel= |
plasticity=more plastic, less ability to differentiate differentiated=less plastic Glia=unipotent astrocytes=terminally diff. blastocyst=mammalian version of blastula blastocoel=space in middle |
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Ethics of ESC use Two moral principles: What moral Status does the human embryo have: 1. 2. 3. 4.
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1. we, as a people have a moral obligation to relieve suffering 2. We have a duty to respect the value of human life Moral status: 1. full moral status from concept. 2. full more stat. after 14 days 3. increasing status as it develops 4. no moral status prior to birth |
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Compare and Contrast Embryonic Stem Cells and Induced Pluripotent Stem Cells |
Similarities: -both being developed for use in therapy -converted into any type of tissue in the embryo -both ALL pluripotent=KEY similarity Differences: -ES come form blastocysts/blastula stage, IPS derive from differentiated cells=KEY difference -IPS usually unipotent, converted back to pluripotent -IPS cells revert back to pluripotent from differentiation |
