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9 Cards in this Set

  • Front
  • Back
What is a stem cell?
Self renewal indefinitely
Differentiate asymmetrically (Precursor:progenitor)
Give some features of Adult stem cells?
Tissue specific
Can Transplant
Hard to culture
Less controversial
Give some features of Human Embryonic Stem Cells
Pluripotent (220 types)
Host rejection
Easier to culture
Very Very controversial
Give some features of Somatic Cell Nuclear Transfer
Pluripotent
No rejection
Very difficult to culture
Most die in utero
Give some features of Induced pluripotent Stem Cells
Pluripotent
Transplantable
non-oncogenic
Ethically difficult
Complex
Epigenetics
What 4 proteins are critical in the process of inducing a pluripotent stem cell?
Nanog
Sox-2
C-myc
OCT-4
What types of cloning is available and what do they const of?>
Therapeutic cloning

using a somatic cell + Egg = Blastocyst and using the inner cell mass to create differentiated tissues

Reproductive cloning

Same as above except they implant the blastocyst into the Uterus
Name the three primary germ layers and what tissues are derived from each
Ectoderm: Epidermis, CNS, PNS eyelids
Mesoderm: Connecttive tissue, bone, muscle, blood and lymph, kidneys, genitals, spleen, dermis, urinary system
Endoderm: GI epithelium, Liver, Pancreas, uriniary bladder, trachea, thryoid, lungs
What therapeutic potential does SC treatment offer?
Bone marrow transplant - AML/CML lymphoma
Neurology, cancer
Diabetes T1
CHD
Dementia
Drug testing