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9 Cards in this Set
- Front
- Back
What is a stem cell?
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Self renewal indefinitely
Differentiate asymmetrically (Precursor:progenitor) |
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Give some features of Adult stem cells?
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Tissue specific
Can Transplant Hard to culture Less controversial |
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Give some features of Human Embryonic Stem Cells
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Pluripotent (220 types)
Host rejection Easier to culture Very Very controversial |
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Give some features of Somatic Cell Nuclear Transfer
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Pluripotent
No rejection Very difficult to culture Most die in utero |
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Give some features of Induced pluripotent Stem Cells
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Pluripotent
Transplantable non-oncogenic Ethically difficult Complex Epigenetics |
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What 4 proteins are critical in the process of inducing a pluripotent stem cell?
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Nanog
Sox-2 C-myc OCT-4 |
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What types of cloning is available and what do they const of?>
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Therapeutic cloning
using a somatic cell + Egg = Blastocyst and using the inner cell mass to create differentiated tissues Reproductive cloning Same as above except they implant the blastocyst into the Uterus |
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Name the three primary germ layers and what tissues are derived from each
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Ectoderm: Epidermis, CNS, PNS eyelids
Mesoderm: Connecttive tissue, bone, muscle, blood and lymph, kidneys, genitals, spleen, dermis, urinary system Endoderm: GI epithelium, Liver, Pancreas, uriniary bladder, trachea, thryoid, lungs |
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What therapeutic potential does SC treatment offer?
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Bone marrow transplant - AML/CML lymphoma
Neurology, cancer Diabetes T1 CHD Dementia Drug testing |