• Shuffle
    Toggle On
    Toggle Off
  • Alphabetize
    Toggle On
    Toggle Off
  • Front First
    Toggle On
    Toggle Off
  • Both Sides
    Toggle On
    Toggle Off
  • Read
    Toggle On
    Toggle Off
Reading...
Front

Card Range To Study

through

image

Play button

image

Play button

image

Progress

1/413

Click to flip

Use LEFT and RIGHT arrow keys to navigate between flashcards;

Use UP and DOWN arrow keys to flip the card;

H to show hint;

A reads text to speech;

413 Cards in this Set

  • Front
  • Back
INT-7.1. True-False Type Question
Distension is the only natural stimulus which can increase gastric
emptying.
T
INT-7.2. True-False Type Questions
Fats are not effective in slowing down gastric emptying.
F
INT-7.11.
The following statements are all true for Exanthematous Typhus,
EXCEPT:
A) a severe drug-resistant headache typically occurs following the
7- to l4-day incubation period
B) hypotension occurs in the most seriously ill patients
C) exanthema develops at the end of the second week
D) splenomegaly occurs in some cases
E) small pink macules appear on the 4th to 6th day
F) severe diarrhea occurs at the onset of the disease
F) severe diarrhea occurs at the onset of the disease
INT-7.12.
All of the following are true for coccidioidomycosis, EXCEPT:
A) acute bronchitis
B) erythema nodosum
C) leukopenia
D) arthritis
E) a positive complement-binding test and a negative skin-test in
cases of a disseminated infection
C) leukopenia
INT-7.16.
All of the following can cause osteoporosis, EXCEPT:
A) a calcium deficiency
B) a phosphate deficiency
C) hypercortisonism
D) hypogonadism
B) a phosphate deficiency
INT-17.
Which of the following can cause demineralization of the bones?
A) tumors
B) bone marrow diseases
C) hyperparathyroidism
D) a vitamin D deficiency
E) all of the above
E) all of the above
INT 7.18.
All of the following are used to treat osteoporosis, EXCEPT:
A) calcium
B) vitamin D
C) sodium fluoride
D) calcitonin when estrogen therapy is contraindicated
E) potassium
E) potassium
INT-7.20.
All of the following are typical of Wiskott-Aldrich syndrome EXCEPT:
A) chronic eczema
B) thrombocytopenic purpura
C) a sex-dependent recessive inheritance pattern
D) anemia
E) thymus aplasia
E) thymus aplasia
INT-7.21.
Rheumatoid factor usually occurs together with the following symptoms
EXCEPT:
A) subcutaneous nodules
B) splenomegaly
C) vasculitis
D) neuropathy
E) juvenile rheumatoid arthritis
F) Sjorgen's syndrome
F) Sjorgen's syndrome
INT-7.26.
Select the most important restricting side-effect of chloroquine,
when used for systemic lupus erythematosus (SLE) therapy:
A) cardiotoxicity
B) hepatotoxicity
C) ocular toxicity
D) peripheral neuropathy
E) drug fever
C) ocular toxicity
INT-7.28.
All of the following are true for osteogenesis imperfecta, EXCEPT:
A) progressive deafness
B) blue sclerae
C) a soft skull with "wormian" bones
D) multiple fractures
E) cataracts
E) cataracts
INT-7.30.
Impetigo is a superficial infection caused by one of the following bacteria:
A) hemolytic staphylococcus
B) hemolytic streptococcus group A
C) both of the above
D) none of the above
C
INT-7.32.
Streptococcus infections can cause the following diseases EXCEPT:
A) lymphangitis
B) puerperal infections
C) erysipelas
D) pyelonephritis
D) pyelonephritis
INT-7.33.
Which site (excluding the lung) is mainly affected by childhood pulmonary
tuberculosis?
A) the mediastinal lymph nodes
B) the kidney
C) the spine
D) the pericardium
E) the peritoneum
A) the mediastinal lymph nodes
INT-7.34.
All of the following alterations occur in syphilis, EXCEPT:
A) condyloma latum
B) mucocutaneous pustular lesions
C) gumma
D) meningitis
E) uveitis
F) condyloma acuminatum
F) condyloma acuminatum
INT-7.35.
All of the following changes are typical of tabes dorsalis, EXCEPT:
A) piercing pain
B) ataxia
C) neurogenic bladder
D) Argyll-Robertson's pupil
E) most of the serological reactions of the serum and CSF are
positive
E
INT-7.38.
All of the following are typical of endogenous pyrogens, EXCEPT:
A) they are low molecular weight proteins
B) they are similar to lysozyme
C) they are heat labile
D) they elicit fever
E) they are inhibited by an endotoxin
E) they are inhibited by an endotoxin
INT-7.41.
All of the following are opiate withdrawal symptoms, EXCEPT:
A) yawning and rhinorrhea
B) sweating and lacrimation
C) dilated pupils
D) piloerection
E) myalgia
F) hypothermia
F) hypothermia
INT-7.45.
Which of the following ECG findings does not occur in right ventricular
hypertrophy?
A) ST depression in II, III, aVF
B) qR complex in V1

C) SI, QIII
D) ST depression in V5-6

E) right axis deviation
D) ST depression in V5-6
INT-7.47.
If the mother has measles during the first trimester of pregnancy all
of the following can occur in the newborn, EXCEPT.
A) cardiac disorders
B) cataracts
C) thrombocytopenic purpura
D) deafness
E) the measles virus cannot be identified in newborns
E) the measles virus cannot be identified in newborns
INT-7.48.
All of the following are contraindications of the viable measles vaccine,
EXCEPT:
A) pregnancy
B) leukemia
C) active tuberculosis
D) simultaneous steroid therapy
E) polio vaccination performed 4 weeks before
E) polio vaccination performed 4 weeks before
INT-7.49.
All of the following are useful symptoms which help to differentiated
acute pancreatitis from a perforated peptic ulcer, EXCEPT:
A) hypertension develops in acute pancreatitis
B) a perforated ulcer is more pressure sensitive
C) intestinal sounds are typical of acute pancreatitis
D) in perforated peptic ulcer air is visible under the diaphragm,
while in acute pancreatitis pleural effusion is typical
E) an elevated serum amylase level
E) an elevated serum amylase level
INT-7.53.
Which of the following can cause postoperative hypokalemic,
hypochloremic alkalosis?
A) dehydration due to artificial nutrition
B) acute renal insufficiency
C) unrecognized diarrhea
D) nasogastric catheter
E) overnutrition
D) nasogastric catheter
INT-7.54.
Select the pCO2
value characteristic of pure metabolic alkalosis if
the serum bicarbonate value is 34 mmol/L?
A) 20 mmHg
B) 30 mmHg
C) 40 mmHg
D) 60 mmHg
E) 70 mmHg
C) 40 mmHg
INT-7.55.
In gastric fluid loss, all of the following can occur, EXCEPT:
A) an increased urine pH
B) a decreased urine potassium level
C) an increased urine bicarbonate level
D) a decreased urine chloride level
E) increased renin secretion
B) a decreased urine potassium level
INT 7.56.
Metabolic alkalosis occurs in all of the following, EXCEPT:
A) diabetes mellitus
B) pyloric stenosis
C) Bartter's syndrome
D) after administration of calcium carbonate
E) as a side-effect of ethacrynic acid therapy
A) diabetes mellitus
INT-7.61.
Case Study:
A patient with chronic metabolic acidosis treated with alkalic
equivalents to correct the acidosis kept hyperventilating for several
days. Which of the following is the most typical finding in this case?
A) pH 7.4; pCO2 40; HCO3
24
B) pH 7.5; pCO2 40; HCO
3
30
C) pH 7.5; pCO2 20; HCO
3
16
D) pH 7.3; pCO2 30; HCO
3
14
E) pH 7.5; pCO2 50; HCO
3
36
C) pH 7.5; pCO2 20; HCO
3
16
INT-7.62.
Which of the following can occur if the pCO2
is 70 mmHg and the
bicarbonate level is 33 mmol/L?
A) chronic respiratory acidosis
B) acute respiratory acidosis
C) respiratory and metabolic acute acidosis
D) respiratory acidosis and metabolic alkalosis
E) none of the above
A) chronic respiratory acidosis
INT-7.63.
The anion gap can be increased in:
A) ammonium chloride intoxication
B) pyloric stenosis
C) bromide intoxication
D) multiple myeloma
E) liver cirrhosis
B) pyloric stenosis
INT-7.70.
Which of the following statements about uric acid transport is FALSE?
A) uric acid is reabsorbed and secreted by the renal tubules
B) transport mainly occurs in the proximal part of the nephron
C) changes in glomerular filtration do not significantly regulate
the urate clearance
D) urate clearance increases with the increase of urine flow
E) urate is mainly transported by diffusion
E) urate is mainly transported by diffusion
INT-7.71.
According to data obtained in many hospital patients, hyperuricemia
is primarily caused by:
A) chronic renal insufficiency
B) poorly treated hypertension
C) chronic diuretic therapy
D) obesity and an increased consumption of purines
E) diabetes mellitus in adults
C) chronic diuretic therapy
INT-7.73. Single Choice Question
Which of the following statements about uric acid transport is FALSE?
A) interstitial uric acid concentration is highest in the
juxtamedullary region
B) in proximal tubuh the uric acid transport occurs in both
directions
C) hyperthyroidosis increases the uric acid clearance
D) pyrazinoate mainly decreases the uric acid secretion
E) acetazolamide slightly increases the uric acid excretion
A) interstitial uric acid concentration is highest in the
juxtamedullary region
INT-7.81.
Which of the following is accompanied by a low uric acid level?
A) diabetes without glucosuria
B) diabetic ketoacidosis
C) diabetic nephropathy
D) Hodgkin's disease
E) none of the above
D) Hodgkin's disease
INT-7.86.
Which of the following statements about glucose reabsorption is FALSE?
A) glucose is reabsorbed with limited active transport
B) the glucose carrier is unknown
C) the Tin glucose value is about 300 mg/min
D) phlorhizin decreases the glucose/insulin ratio
E) under normal conditions only trace amounts of glucose appear
in the urine
D) phlorhizin decreases the glucose/insulin ratio
INT-7.87.
In diabetic ketoacidosis, the normalization of dehydration affects
glucosuria in the following way:
A) it increases glucosuria
B) it decreases glucosuria
C) the glucosuria remains unchanged
D) the glucosuria decreases if the blood glucose level decreases
E) the glucosuria disappears
A) it increases glucosuria
INT-7.89.
Which of the following physiological sequences indicates the effect of
a diuretic on the proximal tubule?
A) a significant phosphaturia
B) adecreased free water clearance
C) hyperkalemia
D) the fractional bicarbonate excretion is under 0.2
E) a metabolic alkalosis
A) a significant phosphaturia
INT-7.93.
Which of the following statements about the antihypertensive effect
of diuretics is FALSE?
A) a decreased plasma renin level
B) . a decreased cardiac output
C) decreased extracellular fluid
D) decreased peripheral resistance
E) a decreased sensitivity to vasoconstrictor agents
A) a decreased plasma renin level
INT-7.96.
All of the following are side-effects of thiazide diuretics EXCEPT:
A) transient myopia
B) hearing loss
C) central visual disorders
D) agranulocytosis
E) thrombocytopenia
B) hearing loss
INT-7.99.
The main mechanism of action of the thiazide diuretics is on:
A) the thin segment of the loop of Henle
B) the pyramids
C) the collecting duct
D) the whole nephron
E) the early portion of the distal tubule
E) the early portion of the distal tubule
INT 7.103.
Which of the following agents is not contraindicated in severe renal
insufficiency?
A) furosemide
B) spironolactone
C) triamterene
D) amiloride
E) potassium tablets (with a long-term effect)
A) furosemide
INT-7.106.
Chronic thiazide therapy can cause all of the following symptoms,
EXCEPT:
A) an increased excretion of bicarbonate
B) a decreased excretion of calcium
C) a decreased excretion of uric acid
D) a decreased excretion of potassium
E) an increased excretion of chloride
D) a decreased excretion of potassium
INT-7.108.
Which of the following statements about furosemide is FALSE?
A) in a maximum dose furosemide is more effective than the
thiazides
B) furosemide is efficient even at very low filtration rates
C) it increases RBF and GFR if severe hypovolemia is not present
D) it maintains the concentrating capacity of the kidney
E) other diuretics potentiate it's effect
D) it maintains the concentrating capacity of the kidney
INT 7.110.
The chronic administration of furosemide can cause all of the following
symptoms, EXCEPT:
A) hypokalemia
B) hypochloremia
C) hypomagnesiemia
D) hypocalcemia
E) hyperchloremia
E) hyperchloremia
INT-7.111.
Furosemide inhibits:
A) chloride transport in the ascending loop of Henle
B) potassium transport in the distal tubules
C) sodium transport in the collecting ducts
D) potassium transport in the proximal tubules
E) potassium transport in the collecting duct
A) chloride transport in the ascending loop of Henle
INT-7.112.
Furosemide:
A) decreases renal blood flow
B) increases renal blood flow without increasing the GRF
C) can produce a metabolic acidosis
D) promotes chloride reabsorption in the loop of Henle
E) large doses promote uric acid reabsorption
B) increases renal blood flow without increasing the GRF
INT-7.114.
Spironolactone-induced full-scale sodium excretion occurs:
A) within 10-30 min.
B) within 2-4 hours
C) within 12-20 hours
D) within several days
E) none of the above
D) within several days
INT-7.116.
Case Study:
A 35-year-old male patient complains of a resistant limb edema which
has persisted for many years. He spent most of his life in tropical
countries. His urine is milk-like. Which of the following explains the
pathological changes of his urine?
A) lipiduria
B) a urinary tract infection
C) gonorrhea
D) chyluria
E) an increased consumption of milk
D) chyluria
INT-7.117.
Case Study:
A 25-year-old unconscious female patient was admitted to the hospital.
No friends or witnesses could give any further information on what
had happened Centrifugation of the urine obtained by catheter revealed
fat drops in the sample. Which of the following diagnoses is
possible?
A) eclampsia
B) bone fracture
C) CO intoxication
D) all of the above
E) none of the above
D) all of the above
INT-7.118.
Case Study:
Nephrosis was diagnosed in a 15-year-old boy. A renal biopsy revealed
a "minimal change" process. The creatinine clearance determined from
a timed urine sample while the patient remained recumbent was 150
ml/min. Select the possible cause of the high creatinine clearance rate:
A) an increased permeability of glomeruo-capillary surface
B) inaccurate urine sampling
C) a decreased plasma osmotic pressure in the glomeruli
D) an increased renal blood flow (RBF)
E) an increased transcapillary hydrostatic pressure
C) a decreased plasma osmotic pressure in the glomeruli
INT-7.121.
Case Study:
A 26-year-old female patient is admitted due to a suspected nephrotic
syndrome. The determination of the different molecular mass protein
clearance indicated an albumin predominance. High molecular-mass
globulins were not found in the urine. Select a possible diagnosis:
A) membranous glomerulopathy
B) proliferative glomerulonephritis
C) a "minimal change" process
D) membranoproliferative glomerulonephritis
E) focal glomerulonephritis
C) a "minimal change" process
INT-7.125.
Case Study:
A routine test has revealed proteinuria in a 35-year-old male patient.
Electrophoresis of the urine proteins showed low molecular proteins
at high concentration and only sustained albuminuria. RIA
(radioimmunoassay) identifiedthe predominance of beta 2-
microglobulins. Which of the following caused the proteinuria?
A) cadmium intoxication
B) mercury intoxication
C) penicillin intoxication
D) glomerulonephritis
E) none of the above
A) cadmium intoxication
INT-7.129.
Case Study:
A 47-year-old diabetic patient developed oliguria after intravenous
urography. The urine osmolarity was 480 mOsm. The most probable
diagnosis is:
A) acute renal insufficiency
B) prerenal azotemia
C) papillary necrosis
D) diabetic nephropathy
E) obstructive uropathy
A) acute renal insufficiency
INT-7.136.
Case Study:
In a patient with severe hypertension a normal creatinine level and a
4 g/24h proteinuria were found. Urography revealed an enlarged (16
cm) right kidney and a smaller (7 cm) left kidney with a blurred border.
Results of arteriography suggest stenosis of the right renal artery.
Which of the following should be the next adequate study?
A) a bilateral retrograde urography
B) a right-sided percutaneous renal biopsy
C) left-sided percutaneous renal biopsy
D) a right-side biopsy with surgical approach
E) the determination of the renin concentration in the renal veins
E) the determination of the renin concentration in the renal veins
INT-7.145.
Case Study:
A 45-year-old patient's blood pressure is 140/95 (stage 4); the patient
has no other risk factors. Which of the following should be performed
after a 6-month observation period?
A) propranolol therapy should be started
B) potassium chloride therapy should be started
C) diuretic therapy combined with a reduced sodium uptake
should be started
D) the stage-5 diastolic pressure should be checked
E) a larger cuff should be used and the patient's ECG should be taken
D) the stage-5 diastolic pressure should be checked
INT-7.148.
Which of the following statements about hypertension is FALSE?
A) if the diastolic pressure is over 90 mmHg, life expectancy is
always reduced in all patients
B) the official WHO definition of normotension is: systolic pressure
140-160 mmHg; diastolic pressure 90-95 mmHg
C) the rate of pressure increase is higher in pre-existing hypertension
D) females tolerate hypertension better than males
E) 15-20% of the adult population in the USA is hypertensive
B) the official WHO definition of normotension is: systolic pressure
140-160 mmHg; diastolic pressure 90-95 mmHg
INT-7.149.
Which of the following statements is true for a "borderline" hypertension?
A) the cardiac output is usually increased
B) the blood volume is usually increased
C) the peripheral vascular resistance is usually increased
D) there is an increased role of the alpha-adrenergic nervous system
E) these patients are usually resistant to beta-blockers
A) the cardiac output is usually increased
INT 7.151.
Which of the following pressure ranges is considered "borderline hypertension"
in young patients?
A) 140/90-160/95 mmHg
B) 120/80-140/90 mmHg
C) 120/80-165/90 mmHg
D) 130/85-140/95 mmHg
E) 130/85-139/89 mmHg
A) 140/90-160/95 mmHg
INT-7.152.
The blood pressure can increase:
A) in obesity
B) after consumption of substantial amounts of alcohol
C) due to smoking
D) in gout
E) all of the abov
E
INT-7.162.
Which of the following statements about the baroreceptors of the
carotid sinus and the aortic arch is FALSE?
A) in animals full denervation causes constant hypertension
B) the baroreceptor sensitivity slightly decreases in essential hypertension
C) the baroreceptor activity can increase in young individuals
with "borderline hypertension"
D) at decreased baroreceptor activity, the peripheral resistance
and diastolic pressure can markedly increase in the
orthostatic position
E) a higher pressure is necessary to activate baroreceptors in hypertension
D
INT-7.163.
All of the following hormones participate in the regulation of blood
pressure in humans, EXCEPT:
A) adrenaline
B) noradrenaline
C) renin
D) vasopressin
E) aldosterone
C) renin
INT-7.164.
Catecholamines exhibit all of the following effects, EXCEPT:
A) anxiety followed by hyperventilation, palpitation and tremor
B) a long-term elevation of blood pressure
C) an increased cardiac output
D) an increased muscle blood flow
E) an increased renal blood flow
E) an increased renal blood flow
INT-7.166.
In which of the following diseases does kallikrein secretion decrease?
A) essential hypertension
B) pheochromocytoma
C) primary aldosteronism
D) all of the above
E) none of the above
A) essential hypertension
INT-7.167.
Angiotensin infusion administered to normotensive patients can
cause all of the following symptoms, EXCEPT:
A) an increased glomerular filtration rate (GFR)
B) a decreased renal salt excretion
C) a decreased renal blood flow (RBF)
D) antidiuresis
E) an increased prostaglandin production
A) an increased glomerular filtration rate (GFR)
INT-7.168.
Which of the following statements is true for angiotensin I?
A) it is the most potent vasoconstrictor known
B) it is activated by the liver converting enzymes
C) it consists of 10 aminoacids
D) it stimulates aldosterone release
E) it is formed from the "big renin"
C) it consists of 10 aminoacids
INT-7.170.
Which of the following statements about angiotensinogen (renin
substrate) is FALSE?
A) it is mainly produced in the liver
B) its concentration is markedly increased after bilateral
adrenalectomy
C) its concentration remains unchanged after bilateral adrenalectomy
D) its concentration decreases in liver cirrhosis
E) estrogens increase its level
B) its concentration is markedly increased after bilateral
adrenalectomy
INT-7.175.
In which of the following is the angiotensinogen (renin substrate)
level abnormally high?
A) during estrogen therapy
B) Hodgkin's disease
C) colitis
D) essential hypertension
E) leukemia
A
INT-7.176.
The aldosterone level is always increased in:
A) essential hypertension
B) malignant hypertension
C) pheochromocytoma
D) Liddle's syndrome
E) polycystic kidney disease
B) malignant hypertension
INT-7.185.
In which of the following diseases does the plasma renin level always
remain low?
A) essential hypertension
B) aortic coarctation
C) pheochromocytoma
D) Conn's syndrome
E) Cushing's syndrome
D) Conn's syndrome
INT-7.187.
What is the most common cause of cerebral hemorrhage in hypertension?
A) atheroma
B) berry aneurysm
C) Charcot-Bouchard aneurysm
D) rupture of arteriosclerotic vessels
E) a thrombosis
C) Charcot-Bouchard aneurysm
INT-7.188.
Which of the following renal biopsy findings is the least probable in
a patient with severe hypertension, papilla edema, and uremia?
A) glomerular proliferation
B) focal necrotizing glomerulonephritis
C) marginal leukocytosis
D) arteriolar hyaline formation
E) fibrinoid deposits and polymorphonucleocytes in the arteriolar
wall
C) marginal leukocytosis
INT-7.191.
Case Study:
A 32-year-old male patient complains of various fits of hypertension
and headaches. The repeatedly determined urine and plasma
vanillylmandelic acid, catecholamine, and metanephrine values were
normal. Select a possible explanation:
A) cerebral astrocytoma
B) a non-functioning adrenal tumor
C) aortic coarctation
D) aberrant adrenal tissue
E) an inadequate sampling of the urine
A) cerebral astrocytoma
INT-7.192.
Case Study:
The blood pressure of a pregnant woman (24th week of gestation)
was 170/ 100 mmHg. Select a possible explanation:
A) borderline or mild hypertension
B) pseudohypertension of pregnancy
C) hyperkinetic syndrome
D) severe hypertension
E) sustained hypertension
D
INT 7.193.
Which drugs or drug combinations should be avoided in the therapy
of pheochromocytoma?
A) dibenzyline
B) beta-blockade followed by alpha blockade
C) alpha-blockade followed by beta blockade
D) prazosin
E) clonidine
B) beta-blockade followed by alpha blockade
INT-7.194.
Which of the following studies will yield pathological values in
neurofibromatosis with hypertension?
A) the determination of the concentration of metanephrine in a
24-hour urine sample
B) the plasma renin activity
C) the serum cortisol level
D) the determination of the concentration of aldosterone in a 24-
hour urine sample
E) the fractional potassium excretion
A) the determination of the concentration of metanephrine in a
24-hour urine sample
INT-7.195.
In which of the following diseases, (which are accompanied with
orthostatic hypertension), does hyperglycemia, glucosuria,
hypermetabolism, and type-II multiple endocrine neoplasm occur?
A) Cushing's disease
B) essential hypertension
C) malignant hypertension
D) pheochromocytoma
E) cerebellar hemangioblastoma
D) pheochromocytoma
NT-7.196.
Which of the following substances can erroneously alter the
vanilly1mandelic acid values ?
A) methyldopa
B) MAO-inhibitors
C) clofibrate
D) ethanol
E) nitroglycerin
E) nitroglycerin
INT-7.200.
Foamy cells occur in all of the following, EXCEPT:
A) chronic glomerulonephritis
B) lipoid nephrosis
C) membranous glomerulonephritis
D) hereditary nephritis
E) nephrosclerosis
E) nephrosclerosis
INT-7.202.
Which of the following symptoms does not occur in nephroptosis?
A) abdominal seizures in the orthostatic position
B) postural hypertension
C) postural hyperaldosteronism
D) abdominal pain in Trendelenburg's position
E) renal insufficiency
E
INT-7.203.
All of the following symptoms occur in renal vein thrombosis, EXCEPT:
A) severe lumbar pain
B) ureter incisure on the intravenous pyelogram
C) hematuria
D) proteinuria
E) medial deviation of the ureter
E) medial deviation of the ureter
INT-7.204. Single Choice Question
Renal vein thrombosis can be a complication of all of the following
EXCEPT:
A) hypernephroma
B) congestive cardiac failure
C) in a patient in the terminal state of papillary necrosis
D) nephrosclerosis
E) nephrosis syndrome
D) nephrosclerosis
INT 7.206.
Primary renal impairment in disseminated intravascular thrombosis
is due to:
A) a hyaline thrombus
B) swelling of the endothelial cells
C) the formation of "half-moon" lesions
D) the rupture of basal membrane
E) the proliferation of mesangial cells
B) swelling of the endothelial cells
INT-7.207.
Which of the following changes is considered a late complication of
the hemolytic-uremic syndrome of infants?
A) anemia
B) thrombocytopenia
C) hypertension
D) intravascular coagulation
E) none of the above
C) hypertension
INT-7.215.
Which of the following substances does not occur in the urine in
Hartnup disease?
A) histidine
B) tryptophan
C) phenylalanine
D) methionine
E) arginine
E) arginine
INT-7.216.
Which of the following remarks about proximal tubular acidosis is FALSE?
A) a decreased proximal maximum bicarbonate reabsorption
B) an intact distal acidifying system
C) after administration of ammonium chloride the urine pH value
becomes less than 5.4
D) an increased bicarbonate excretion in the urine
E) an impaired distal acidifying system
E) an impaired distal acidifying system
INT-7.221.
Case Study:
A 55-year-old patient has a primary carcinoma of unknown origin.
Which of the following is totally resistant to therapy?
A) adenocarcinima of the prostate
B) adenocarcinoma of the lung
C) adenocarcinoma of the breast
D) germinal cell carcinoma
E) carcinoma of the thyroid gland
B
INT-7.222.
Eosinophilia primarily occurs in:
A) enterobiasis
B) diarrhea due to Giardiasis (lambliasis)
C) Schistosomiasis
D) measles
E) corticosteroid therapy
C) Schistosomiasis
INT-7.223.
All of the following can occur as a complication of chronic obstructive
pulmonary disease EXCEPT:
A) cor pulmonarye
B) polycythemia
C) respiratory insufficiency
D) left ventricular insufficiency
E) bronchogenic carcinoma
D
INT-7.224.
Chronic obstructive pulmonary disease (COPD) can be either
emphysematous or bronchitic, depending on the character of the pathological
alterations in the lung. Though they rarely occur as autonomous
forms, the two diseases can be differentiated on the basis of
their clinical manifestation. Select the most common feature characteristic
of emphysematous and bronchitic COPD:
A) polycythemia
B) bronchodilators can improve the airflow
C) dyspnea
D) a chronic cough
E) hypercapnia
C
INT-7.226.
Immune deficiency is diagnosed if:
A) the functional activity of the T lymphocytes cannot be identified
neither in vivo, nor in vitro
B) there is a decrease of antibody production
C) the T cells cannot change the yellow color of nitro-blue
tetrazolium into blue
D) neutrophil and macrophage migration is lower than the
chemotaxis stimulus
E) no hemolysis can occur if the serum of the patient is added to
an RBC-anti-RBC antibody system
A
INT-7.228.
Case Study:
A 50-year-old female patient complains of redness, swelling and rigidity
of the distal interphalangeal joints. She has no other
arthralgias. The most probable diagnosis is:
A) erosion osteoarthritis
B) rheumatoid arthritis
C) systemic lupus erythematosus (SLE)
D) ankylosing spondylitis
E) systemic sclerosis
A
INT-7.231.
Which of the following findings permits a differentiation between
painless thyroiditis and Graves disease?
A) an enlarged thyroid gland
B) a low serum TSH level
C) an increased serum thyroxine level
D) a low uptake of radioactive iodine
E) pressure tenderness and pain in the thyroid gland
D
INT-7.232.
Which of the following statements is the most typical feature of an
amebic liver abscess?
A) that surgical drainage is necessary
B) it can be caused by one of the six ameba types
C) in the USA it commonly occurs among homosexuals and hospital
patients
D) it usually indicates an intestinal amebic infection
E) it usually occurs in patients with normal serum alkalic
phosphatase levels but elevated transaminase levels
C
INT-7.233.
All of the following participate in the pathomechanism of an immediate
type hypersensitivity reaction EXCEPT:
A) serotonin
B) bradykinin
C) anaphylactic eosinophilic chemotactic factor
D) basophilic chemotactic factor
E) neutrophilic chemotactic factor
D
INT-7.234.
All of the following clinical alterations occur in patients with pulmonary
embolism EXCEPT:
A) hypoxia
B) insufficiency of the right heart
C) cyanosis
D) deep vein thrombosis
E) bradycardia
E) bradycardia
INT-7.235.
Case Study:
A patient with chronic renal insufficiency due to severe chronic hypertension
is examined for chest pain. For the last 2 years the patient
has been undergoing hemodialysis twice a week. Hypotensive episodes
occurred several times during dialysis. The chest pain is localized above
the trapezius muscle; in an orthostatic position it decreases, and during
deep inspiration it increases. Select the most probable cause of
this chest pain:
A) pericarditis
B) coronary disease
C) diffuse esophageal spasm
D) pulmonary embolism
E) costochondritis
A
INT-7.236.
The cornea is involved in which of the following:
A) sarcoidosis
B) hypercholesterolemia
C) congenital syphilis
D) tuberculosis
E) pneumocystosis
A) sarcoidosis
INT-7.242.
The most common hepatic lesion in cystic fibrosis is:
A) postnecrotic cirrhosis
B) fat atrophy
C) multinodular biliary cirrhosis
D) Laennec's cirrhosis
E) none of the above
C
INT-7.243.
Which of the following cardiac surgical interventions causes jaundice?
A) pulmonary valve repair
B) aortic valve repair
C) mitral valve repair
D) tricuspid valve repair
D) tricuspid valve repair
INT-7.245.
All of the following can cause mechanical ileus EXCEPT:
A) cholera
B) hernia
C) carcinoma
D) volvulus
E) gallstones
A
INT-7.246.
All of the following can be caused by a gallstone EXCEPT:
A) biliary cirrhosis
B) acute pancreatic necrosis
C) atrophic cirrhosis
D) chronic cholecystitis
C) atrophic cirrhosis
INT-7.247.
Which of the following is affected in Dupuytren's contracture?
A) the tendons
B) the muscles
C) the palmar fascia
D) the joint
E) the meniscus
C) the palmar fascia
INT-7.248.
Dupuytren's contracture:
A) is a congenital pathology
B) causes extension contracture of the fingers
C) occurs in pseudosarcomatous fibromatosis
D) is caused only by mechanical factors
E) is more common in wome
C) occurs in pseudosarcomatous fibromatosis
INT-7.249.
All of the following cause osteoplastic bone metastases, EXCEPT:
A) gastric cancer
B) breast cancer
C) bronchial cancer
D) prostate cancer
E) hypernephroma
E) hypernephroma
INT-7.251.
Select the correct localization of a concretion in case of hydrops
vesica felleae:
A) the hepatic duct
B) the cystic duct
C) the common bile duct
D) Vater's papilla
E) Wirsungian's duct
B) the cystic duct
INT-7.252.
Combined tumors of the salivary gland:
A) usually have a submaxillary localization
B) are usually malignant
C) usually develop in the parotid gland
D) usually cause facial nerve paralysis
E) typically cause sialolithiasi
C) usually develop in the parotid gland
INT-7.253.
Select the correct term for transplantation of tissue-friendly foreign
materials:
A) replantation
B) alloplasty
C) homologous transplantation
D) autogenous transplantation
E) isologous transplantation
B) alloplasty
INT-7.254.
Select the single correct statement:
A) preblastomatosis is a pathological alteration preceding skin
cancer
B) preblastomatosis is a pathological alteration which leads to the
development of a tumour
C) preblastomatosis is a long-term pathological alteration which
does not lead to malignancy
D) preblastomatosis means pre-invasive cancer
E) hematologic myeloid tumors are defined as preblastomatosis
B
INT-255.
Pneumothorax can be caused by all of the following EXCEPT:
A) trauma
B) bullous emphysema
C) damage of the thoracic duct
D) intersitial emphysema
E) positive pressure artificial ventilation
C) damage of the thoracic duct
INT 7.256.
Case Study:
A round-shaped shadow of 3 cm in diameterwas found on an X-ray screening
of a 65-year-old, complaint-flee, smoking male patient. 15 years ago
the patient had undergone a successful operation for colon carcinoma.
Select the most probable diagnosis:
A) tuberculosis
B) carcinoma metastasis
C) aspiration pneumonia
D) bronchial carcinoma
E) pulmonary absces
D) bronchial carcinoma
INT-7.257.
All of the following are typical of Graves' disease, EXCEPT:
A) obesity
B) goiter
C) left ventricular hypertrophy
D) exophthalmus
A) obesity
INT-7.258.
The most common cause of Addison's disease is:
A) autoimuune adrenal atrophy
B) amyloid accumulation in the adrenals
C) tumor metastasis in the adrenals
D) bilateral adrenal apoplexia
E) adrenal tuberculosis
A) autoimuune adrenal atrophy
NT-7.259.
Which of the following hormones is increased in Conn's syndrome?
A) cortisol
B) adrenaline
C) noradrenaline
D) aldosterone
E) cortisone
D) aldosterone
NT-7.260.
Case Study:
Marked hypertension and its sequels, as well as polyuria and pplydipsia
were found in a middle-aged patient. serum Na: 152 mmol/L; serum
K: 2,2mmo1/L. Select the correct diagnosis:
A) Cushing's syndrome
B) diabetes mellitus
C) Addison's disease
D) Conn's syndrome
E) phaeochromocytoma
D) Conn's syndrome
INT-7.261.
Xanthoma is common in:
A) diabetes insipidus
B) acute hemorrhagic pancreatitis
C) diabetes mellitus
D) diffuse acute glomerulonephritis
E) liver cirrhosis (Laennec's)
C
INT-7.262.
Case Study:
A patient's auricular cartillage has a brownish color, the urine sample
turns brown after a while, and the patient complains of
arthralgia. Select a correct diagnosis:
A) erythropoietic porphyria
B) gout
C) ochronosis
D) cystinosis
E) hemoglobinuria
C) ochronosis
INT 7.263
Which of the following statements is not typical of post-hepatic jaundice?
A) acholic stool
B) direct positive diazo-reaction
C) cholemia
D) increased bilirubin in the urine
E) increased urobilinogen in the urine
E
INT-7.264.
In all of the following melanine is accumulated in the skin, EXCEPT:
A) Mongolian spot
B) vitiligo
C) nevus coeruleus (blue nevus)
D) ephelis (freckle)
E) chloasma (melasma)
B) vitiligo
INT-7.265.
Define the term vitiligo:
A) a generalized lack of melanin in the skin
B) a circumscribed lack of melanin in the skin
C) lipopigment
D) reaction in the peritraumatic areas
E) a degeneration of trophoblasts
B
INT-7.266.
Which of the following statements is typical of albinism?
A) a,tyrosinase enzyme deficiency
B) a decreased level of glucuronide-transferase
C) a decreased level of ceruloplasmin
D) a Kayser-Fleischer circle
E) liver cirrhosis
A) a,tyrosinase enzyme deficiency
INT-7.270.
Which of the following can occur in chronic systemic congestion?
A) thickening of the alveolar walls
B) esophagus varicosity
C) pulmonary edema
D) spot-like hemorrhages of the gastric mucosa
E) kidney micro-infarctions
D) spot-like hemorrhages of the gastric mucosa
INT-7.275.
Define the term "phlebolith":
A) an organized thrombus
B) a venous stone
C) calcification of the venous wall
D) inflammation of the vein wall
E) the inflammation of a thrombus
B
INT-7.277.
In which of the following should generalized mycosis be suspected?
?r) hypertensive disease
B) cardiac decompensation
C) gastric ulcer
D) long-term antibiotic therapy
E) diabetes insipidus
D) long-term antibiotic therapy
INT-281.
Hematuria is typical of all of the following diseases, EXCEPT:
A) acute glomerulonephritis
B)acute pyelonephritis
C) renal tuberculosis
D) renal calculus
E) renal cancer
B)acute pyelonephritis
INT-7.285.
Initial gonococcemia causes gonorrheal urethritis plus one of the
following:
A) myocarditis
B) endocarditis
C) encephalitis
D) meningitis
E) hepatitis
B) endocarditis
INT-7.286.
Initial gonococcemia causes gonorrheal urethritis plus one of the
following:
A) myocarditis
B) osteomyelitis
C) arthritis
D) parotitis
E) meningitis
C) arthritis
INT-7.288.
The nephrotic syndrome occurs in all of the following, EXCEPT:
A) membranous glomerulonephritis
B) thrombosis of the renal vein
C) paraproteinemic nephrosis
D) cholemic nephrosis
E) Kimmelstiel-Wilson's syndrome
D) cholemic nephrosis
INT-7.289.
In all of the following renal calculi can be formed, EXCEPT:
A) in urinary tract obstruction
B) in congenital metabolic disorders
C) in constant substantial fluid loss
D) along with gallstones
E) in pyelitis
D) along with gallstones
INT-7.290.
The most pronounced enlargement of the lymph nodes occurs in one
of the following types of leukemia:
A) acute lymphoid leukemia
B) chronic myeloid leukemia
C) chronic lymphoid leukemia
D) acute myeloid leukemia
E) erythroleukemia
B) chronic myeloid leukemia
INT-7.292.
Marked splenomegaly occurs in which of the following types of
leukemia?
A) acute lymphoid leukemia
B) acute myeloid leukemia
C) chronic lymphoid leukemia
D) chronic myeloid leukemia
E) polycythemia
D) chronic myeloid leukemia
INT-7.294.
Which of the following is typical of Hodgkin's disease stage II?
A) the involvement of lymph nodes of a single region and the spleen
B) the involvement lymph nodes of a single region on both sides
of the diaphragm
C) the involvement of lymph nodes of several regions on both
sides of the diaphragm
D) the involvement of lymph nodes of several regions on both
sides of the diaphragm, and alterations in the spleen
E) the involvement of lymph nodes of several regions on one side
of the diaphragm
E
INT-7.297.
Pulmonary emboli originate from:
A) the femoral artery
B) the femoral vein.
C) one of the pulmonary veins
D) the brachiocephalic trunk
E) none of the above
B
INT-7.300.
Which of the following processes can cause serous pleuritis?
A) bronchopneumonia
B) lobar pneumonia
C) tuberculosis
D) lung cancer
E) pulmonary abscess
C) tuberculosis
INT-7.301.
Which of the following can lead to the development of chronic cor
pulmonale?
A) lobar pneumonia
B) thromboembolism of the pulmonary vein
C) lung edema
D) chronic pulmonary emphysema
E) bronchopneumonia
D) chronic pulmonary emphysema
INT-7.302.
All of the following occur in Goodpasture's syndrome, EXCEPT:
A) focal glomerulonephritis
B) septic spleen
C) pulmonary fibrosis; induration
D) cutaneous purpura
E) positive berlin-blue staining in the lung parenchyma
B
INT-7.303.
Which of the following can develop after long-term antibiotic
therapy?
A) esophageal candidiasis
B) esophageal stricture
C) corrosive esophagitis
D) achalasia
E) diffuse scleroderma
A
INT-7.308.
Which of the following substances causes coagulation necrosis of
the gastric mucosa?
A) sodium hydroxide (NaOH)
B) phosphorus
C) lead
D) mercury
E) arsenic
D) mercury
INT-7.309.
Case Study:
A patient complains of frequent blushing fits. Asthmatic fits and
profuse diarrhea are also frequent. A physical examination revealed
a harsh murmur above the heart. Select the correct diagnosis:
A) Basedow's disease
B) Carcinoid syndrome
C) Tetralogy of Fallot
D) Polycythemia rubra vera
E) Peutz-Jeghers syndrome
B
INT-7.310.
The Zollinger-Ellison syndrome is caused by:
A) an adenoma of the pancreatic beta cells
B) an adenoma of the pancreatic alpha cells
C) an adenoma of the pancreatic gamma cells
D) a carcinoma of the exocrine pancreas
E) mucoviscidosis
C
INT-7.311.
A dilated, rigid, painless gallbladder (Courvoisier's s sign) and jaundice
is typical of one of the following:
A) infectious hepatitis
B) hepatocellular carcinoma
C) cancer of the pancreas head
D) cancer of the pancreas tail
E) calculus in the Wirsungian's duct
C
INT-7.312.
Which of the following cells primarily infiltrate the portal tract in
acute viral hepatitis?
A) neutrophils
B) eosinophils
C) lymphocytes
D) plasma cells
E) giant cells
C) lymphocytes
INT-7.313.
Coagulopathy developing in obstructive jaundice is due to:
A) secondary thrombocytopenia
B) thrombocytopenia due to decreased vitamin K absorption
C) increased capillary fragility
D) thrombasthenia
E) a low activity of tissue thromboplastin
B
INT-7.314.
Which of the following can cause priapism?
A) syphilis
B) urethritis
C) induratio penis plastica (penal prosthesis)
D) increased libido
E) epispadiasis
B) urethritis
INT-7.315.
Define the term priapism:
A) an extrapyramidal disorder
B) a mental disease
C) pathological erection
D) penis inflammation
E) penis gangrene
C
INT-7.316.
The most important etiological factor of epididymitis is:
A) syphilis
B) gonorrhea
C) brucellosis
D) blastomycosis
E) listeriosis
B
INT-7.317.
Vinyl chloride causes cancer in which organs?
A) the liver
B) the adrenals
C) the colon
D) the thyroid
E) the thymus
B) the adrenals
INT-7.318.
Which of the following substances induces urinary bladder cancer
in humans?
A) p-aminodiphenyl (aniline dyes)
B) benzene
C) hydramine
D) aflatoxin
E) vinyl chloride
A) p-aminodiphenyl (aniline dyes
INT-7.322.
All of the following drugs can elicit systemic lupus erythematosus,
EXCEPT:
A) procainamide
B) hydralazine
C) isoniazide
D) chlorpromazine
E) gold salts
E
INT-7.326.
All of the following comprise different histologic forms of Lupus nephritis,
EXCEPT:
A) focal glomerulonephritis
B) membranous glomerulonephritis
C) membranoproliferative glomerulonephritis
D) microscopic polyarteritis
E) mesangioproliferative nephritis
D
NT-7.327.
All of the following are criteria and symptoms of Mixed Connective
Tissue Disease (MCTD), EXCEPT:
A) Raynaud's symptom
B) swollen hands and fingers
C) myositis
D) esophageal dysmotility
E) xerostomia
E) xerostomia
INT-7.328.
All of the following polysystemic autoimmune diseases contribute to the
development of Mixed Connective Tissue Disease (MCTD), EXCEPT
A) systemic lupus erythematosus (SLE)
B) rheumatoid arthritis
C) progressive systemic sclerosis (scleroderma)
D) Sjörgen's syndrome
E) polymyositis/dermatomyositis
D) Sjörgen's syndrome
INT-7.329.
All of the following are among the glandular symptoms of Sjörgen's
syndrome, EXCEPT:
A) pharyngitis - bronchitis
B) vulvitis
C) vaginitis
D) pyelitis
E) conjunctivitis
D) pyelitis
INT-7.343.
Which study should be performed if infectious arthritis is suspected?
A) X-ray study
B) scintigraphy
C) articular puncture
D) antibiotic therapy
C) articular puncture
INT-7.344.
All of the following occur in progressive systemic sclerosis
(scleroderma), EXCEPT:
A) pulmonary fibrosis
B) the incidence of antinuclear autoantibodies in the serum is
about 90%
C) chronic active hepatitis
D) dysmotility of the lower esophageal segment
E) Raynaud's syndrome
C) chronic active hepatitis
INT-7.346.
All of the following diseases can occur in the neonatal period,
EXCEPT:
A) thrombopenia (ITP)
B) myasthenia gravis
C) Basedow's disease
D) pernicious anemia
E) systemic lupus erythematosus (SLE)
D) pernicious anemia
NT-7.350.
The first heart sound is loud in:
A) first degree AV block
B) the Wolff-Parkinson-White (WPW) syndrome
C) mitral stenosis due to calcification
D) aortic stenosis
E) hypertrophic obstructive cardiomyopathy
B) the Wolff-Parkinson-White (WPW) syndrome
INT-7.352.
Which of the following ECG changes are typical of Printzmetal's angina
during a fit?
A) ST depression in a localized area
B) ST elevation in a localized area
C) diffuse ST depression
D) diffuse ST elevation
E) none of the above
B) ST elevation in a localized area
INT-7.353.
Select the most important effect of a normal dose of nitroglycerin in
angina pectoris (apart from coronary dilation!):
A) relaxation of bronchial smooth muscles
B) dilation of the peripheral vessels
C) constriction of the peripheral arterioles
D) constriction of the peripheral venules
E) none of the above
B
INT-7.354.
Select the drug of primary choice in supraventricular tachycardia
with narrow ventricular QRS complexes:
A) digoxin
B) procainamide
C) dopamine
D) verapamil
E) propranolol
D) verapamil
INT-7.355.
Which of the following most probably occured in the history of a 16-
year-old boy with diabetes mellitus?
A) a recent viral infection
B) an insulin response to a glucose load is about 50% of the normal
C) a decreased energy uptake is required
D) an initiation of biguanide treatment before starting insulin
therapy
E) the patient can participate in physical training lessons and
can participate in other games requiring physical performance
E
INT-7.356.
The typical symptom of ischemic colitis in its acute phase is:
A) steatorrhea
B) a normal X-ray picture after a barium meal
C) nausea and vomiting
D) symptoms of generalized peritonitis
E) hemorrhagic diarrhea
E) hemorrhagic diarrhea
INT-7.357.
Which of the following statements is typical of chronic
granulomatosis?
A) neutrophils cannot phagocyte the bacteria
B) chronically enlarged lymph nodes
C) recurrent candidiasis
D) a dominant inheritance pattern
E) hypogammaglobulinemia
B) chronically enlarged lymph nodes
INT-7.358.
All of the following can increase the normal insulin requirement, EXCEPT:
A) pregnancy
B) infections, fever, sepsis
C) idiopathic spontaneous exacerbations
D) hypothyroidosis
E) burns due to irradiation and ultraviolet damage of the deep
tissues
D) hypothyroidosis
INT-7.359.
All of the following can induce systemic lupus erythematosus (SLE),
EXCEPT:
A) chlorpromazine
B) phenytoin
C) aspirin
D) procainamide
C) aspirin
INT-7.361.
Which of the following antibiotics can form unsoluble chelates with
the aluminium of antacids, which would then impair their absorption?
A) penicillins
B) tetracyclines
C) erythromycin
D) sulfonamides
E) none of the above
B) tetracyclines
INT-7.362.
The occurrence of hemolytic anemia in methyl-dopa therapy is:
A) less than 1%
B) 5%
C) 10%
D) 15%
E) 33%
A) less than 1%
INT-7.363.
Case Study:
Select the drug of choice in .a 2-year-old girl with fever and
polyarthritis (diagnosis: juvenile rheumathoid arthritis):
A) cytozan
B) prednisolone
C) aspirin
D) chloroquine
E) penicillinamine
C) aspirin
INT-7.364.
Which of the following facilitates the antiocoagulant effect of
coumarin?
A) phenylbutazone
B) multivitamins containing vitamin K
C) high-dose salicylate
D) quinine and quinidin
B
INT 7.365.
All of the following increase the blood glucose level, EXCEPT:
A) corticosteroids
B) clofibrate
C) diazoxide
D) lithium carbonate
B) clofibrate
INT-7.366.
Medication recommended for the therapy of pneumococcus pneumonia is:
A) erythromycin
B) streptomycin
C) penicillin G
D) ampicillin
C) penicillin G
INT-7.370.
Where does hypernephroma develop?
A) in the glomerular epithelial cells
B) in the tubular epithelial cells
C) in the epithelial cells of the calyx
D) in the glomerular endothelial cells
E) in the juxtaglomerular apparatus
B) in the tubular epithelial cells
INT-7.376.
Which of the following diseases does not usually lead to the development
of the nephrotic syndrome?
A) glomerulonephritis
B) polycystic kidney
C) renal vein thrombosis
D) - lupus nephritis
E) Kimmensteil-Wilson syndrome
B) polycystic kidney
INT-7.385.
In which of the following diseases does pulmonary hemorrhage occur?
A) systemic lupus erythematosus (SLE)
B) Henoch-Sch6nlein purpura
C) hypersensitive vasculitis
D) Legionnaires' disease
E) all of the above
F) none of the above
E) all of the above
INT-7.387.
Case history:
A 45-year-old male patient suffers for years from rheumatoid arthritis.
Nephrotic edema has recently developed. Urine analysis revealed red
blood cells present in the urine; a 2-hour postprandial serum glucose
was 11 mmol/L. After a 6-week steroid therapy, the proteinuria remained
unchanged. Which of the following diseases is the least probable?
A) amyloidosis
B) chronic membranous nephropathy
C) normal glomeruli as evident by a light microscopic study
D) renal vein thrombosis
E) nodular glomerulonephritis
C
INT-7.389.
Which of the following statements about urinary tract infections in
female patients is FALSE?
A) the occurrence of bacteriuria increases with age
B) a shorter urethra better protects against infections
C) urethral discharge increases the occurrence of bacteriuria
D) a sedentary life-style promotes infection
E) the growing occurrence of bacteriuria with age has no relation
to sexual activity
B
INT-7.390.
Which of the following statements about catheter-induced urinary
tract infections is FALSE?
A) it is the most common nosocomial infection
B) a bladder lavage has a beneficial effect
C) in candida infections systemic amphotericin-B therapy is always
recommended
D) infection induced by short-term catheterization does not require
therapy
E) in candida infections oral therapy with 5-flucytozin is effective
C
INT-7.391.
Which of the following findings indicates analgetic-induced nephropathy?

A) red blood cells-casts
B) oval adipose bodies
C) sterile pyuria
D) phenacetine crystals
E) pigmented hyaline casts
C) sterile pyuria
INT-7.392.
Which of the following drugs does not cause renal disease?
A) penicillin
B) gentamycin
C) erythromycin
D) sulfonamides
E) cephalosporins
C) erythromycin
INT-7.393.
Plasma or tissue erythropoietin-like substances are accumulated in
all of the following diseases, EXCEPT:
A) hypernephroma
B) cerebellar hemangioma
C) hepatoma
D) solitary renal cyst
E) gastric carcinoma
E) gastric carcinoma
INT-7.394.
Case Study:
A 50-year-old agricultural worker was admitted with nausea, vomiting with
a peculiar aftertaste of metal, and diarrhea. He had been working with
insecticides and disinfectants. The serum urea nitrogen value was 25 mmol/L.
The urine volume excreted in 24 h. was 300 ml. Proteinuria, red blood
cellsand epithelial cell casts were observed. Select the correct therapy:
A) monitoring of fluid and electrolyte balance with fluid and electrolyte
replacement therapy if needed
B) high dose steroid therapy
C) a dimercaptol (BAL) injection (3 mg/kg/24 h.)
D) gastric lavage
E) dimercaptol (BAL) injection 3 mg/kg followed by hemodyalisis
E) dimercaptol (BAL) injection 3 mg/kg followed by hemodyalisis
INT-7.401.
Case Study:
A 30-year-old male patient suffers from recurrent renal calculi. An
abdominal X-ray study revealed bilateral nephrocalcinosis. Which of
the following is the least probable?
A) hyperparathyroidism
B) sarcoidosis
C) primary hyperoxaluria (oxalosis)
D) renal tubular acidosis
E) cystinuria
E) cystinuria
INT-7.402.
Which of the following renal calculi are the most common?
A) urate
B) calcium-phosphate
C) mixed calcium-oxalate and calcium-phosphate
D) magnesium ammonium phosphate
E) calcium oxalate
C
INT-7.403.
Which of the following diseases commonly occurs in pregnant
women with renal calculi?
A) pre-eclampsia
B) urinary tract infections
C) spontaneous abortions
D) congenital anomalies
E) renal insufficiency
B
INT-7.404.
Which of the following interventions is not correct in the therapy of
uremic pericarditis?
A) prolonged dialysis
B) anticoagulant therapy
C) formation of a pericardial "window"
D) detachment of the pericardium
E) suction of the pericardial fluid
B) anticoagulant therapy
INT-7.405.
Which of the following drugs causes neuropathy in uremic patients?
A) vibramycin
B) chloramphenicol
C) trimethoprim
D) nitrofurantoin
E) cephalosporins
B) chloramphenicol
INT-7.409.
Which of the following drugs should be markedly decreased in
uremia?
A) gentamycin
B) lincomycin
C) nafcillin
D) oxacillin
E) novobiocin
A) gentamycin
INT-7.410.
All of the following occur in pregnancy, EXCEPT:
A) an increased body water content
B) a decreased blood volume
C) an increased cardiac output
D) an increased renal blood flow
E) an increased GFR
B
INT-7.411.
In pregnancy, limb edema is due to one of the following:
A) salt retention
B) hypoalbuminemia
C) an increased capillary permeability
D) an increased venous pressure
E) an increased blood pressure
D
INT-7.412.
Which of the following usually causes symptom-free bacteriuria during
pregnancy?
A) anemia
B) a premature delivery
C) a congenital anomaly
D) pyelonephritis
E) toxemia
D
INT-7.415.
Which of the following causes cessation of toxemia after delivery?
A) delivery of the placenta
B) delivery of the fetus
C) uterus decompression
D) urether decompression
E) the loss of amniotic fluid
A
INT-7.419.
Which of the following intra-abdominal organs does not move with
respiration?
A) the kidney
B) the pancreas
C) the spleen
D) the transverse colon
E) the stomach
B) the pancreas
INT-7.422.
Which of the following substances is the most potent stimulant of
gastric acid secretion?
A) proteins
B) fats
C) carbohydrates
A) proteins
NT-7.423.
A 5-fold elevation of serum amylase level strongly suggests:
A) parotitis
B) pancreatitis
C) intestinal obstruction
D) pancreatic carcinoma
E) penetrating ulcer
B
INT-7.424.
A characteristic symptom of pyloric obstruction is:
A) bile vomiting
B) abdominal murmurs
C) resonance above Traube's space
D) succussion (splashing sound)
E) visible peristalsis
D
INT-7.426.
In which of the following diseases does a massive gastrointestinal
hemorrhage rarely occur?
A) esophageal varicosity
B) reflux esophagitis
C) gastric ulcer
D) erosive gastritis
B
INT-7.430.
Aluminium-containing antacids decrease the absorption of:
A) atropine
B) iron
C) tetracycline
D) all of the above
E) none of the above
D
INT-7.432.
The diagnosis of malaria is based on:
A) a stained blood smear for the identification of the pathogenic
agent
B) a hemoculture
C) identification of the pathogenic agent on the skin
D) a fluorescent antibody study
A
INT-7.435.
Liver transplantation is a new method for the therapy of fatal liver
diseases. Which of the following markedly improves the post-transplantation
survival rate?
A) a better selection of patients
B) the early recognition of malignant diseases
C) a better understanding of the pathomechanism of liver insufficiency
D) cyclosporine A
D
INT-7.436.
Which part of the colon is the largest feces reservoir?
A) the cecum
B) the transverse colon
C) the descending colon
D) the sigmoid colon
E) the rectum
D) the sigmoid colon
INT-7.437.
The defecation stimulus is triggered by:
A) contraction of the external anal sphincter
B) contraction of the internal anal sphincter
C) distension of the sigmoid colon
D) distension of the rectum
E) contraction of the rectum
D
INT-7.440.
How often (% incidence) does ulcerative colitis affect the
rectosigmoidal mucosa?
A) 10-20%
B) 25-30%
C) 50-70%
D) 70-85%
E) 85-100%
E) 85-100%
INT-7.441.
Which segment of the colon most commonly shows signs of toxic
megacolon or toxic dilation due to ulcerative colitis?
A) the cecum
B) the transverse colon
C) the descending colon
D) the sigmoid colon
E) the rectum
B) the transverse colon
INT-7.446.
Case Study:
A 40-year-old worker had a massive upper gastrointestinal hemorrhage
accompanied by splenomegaly. He never consumed alcohol. Which of the
following could have caused this gastrointestinal bleeding?
A) a peptic ulcer
B) gastritis
C) esophageal varices
D) gastric carcinoma
E) esophagitis
C) esophageal varices
INT-7.447.
In alcoholic cirrhosis and esophageal varicosities:
A) the presence and size of the varices is related to the extent of
hypertension
B) the risk of gastrointestinal hemorrhage correlates with the severity
of portal hypertension
C) the risk of gastrointestinal hemorrhage correlates with the size
of the varices
D) all of the above
E) none of the above
C) the risk of gastrointestinal hemorrhage correlates with the size
of the varices
INT-7.448.
Select the localization of regional enteritis relapsing after
surgery:
A) the jejunum
B) the site of the anastomosis
C) the colon
D) at any site of the gastrointestinal tract
E) the rectum
B
INT-7.451.
Which of the following proteins is not produced by the liver?
A) albumin
B) alphal-globulin
C) alpha 2-globulin
D) beta-globulin
E) gamma-globulin
E) gamma-globulin
INT-7.452.
If a patient with classic reflux esophagitis shows no reaction to
cimetidine or a therapeutic elevation of his bed then therapy must
be supplemented with metoclopramide because:
A) it stimulates gastric evacuation, which is impaired in 50% of
these patients
B) it increases the lower esophageal sphincter tone
C) it improves the acid clearance
D) it improves gastritis which occurs in 75% of these patients
E) all of the above
E
INT-7.454.
The most common endocrinopathy occurring in the Zollinger-
Ellison Syndrome is:
A) pheochromocytoma
B) hyperthyroidism
C) hypopparathyroidism
D) hypoparathyroidism
E) Cushing's syndrome
C) hypopparathyroidism
INT-7.461.
Which of the following statements supports the diagnosis of
hemolytic jaundice?
A) an elevated non-conjugated bilirubin level in the plasma
B) the presence of bilirubin in the urine
C) an elevated reticulocyte count
D) both (A) and (C) are true
E) none of the above
D
INT-7.462.
Case Study:
In a patient with primary biliary cirrhosis, polyclonal gammopathy
was established by protein-electrpphoresis. The immunoglobulin
found is predominantly:
A) IgA
B) IgM
C) IgG
D) IgD
E) IgE
B) IgM
INT-7.464.
Which of the following agents inhibits vitamin B12 absorption?
A) phenytoin
B) methotrexate
C) cycloserine
D) trimethoprim
E) all of the above.,
E) all of the above.,
INT-7.467.
Which of the following endocrine alterations can be accompanied by
an exudative ascites?
A) hyperparathyroidism
B) hyperthyroidism
C) hypothyroidism
D) Addison's disease
E) acromegaly
C) hypothyroidism
INT-7.471.
Case Study:
2 weeks after a coronary bypass operation the patient's SGOT/SGPT
was 30/350 with a normal liver function. 3 months later the patient
complained of fatigue and weakness, his SGPT level increased over
300. Which of the following is the most probable diagnosis?
A) delta-hepatitis
B) B-type hepatits
C) non-A non-B hepatitis
D) CMV hepatitis
E) activation of a chronic hepatitis
C) non-A non-B hepatitis
INT-7.473.
All of the following are clinico-pathological symptoms of lead intoxication,
EXCEPT:
A) anemia with basophilic granules in the red blood cells
B) membranous nephropathy with nephrotic syndrome
C) increased renal excretion of aminolevulinic acid and
coproporphyrin
D) lethargy, stupor, mental retardation and encephalopathy
B) membranous nephropathy with nephrotic syndrome
INT-7.477.
Which of the following alterations is not characteristic of immunodeficient
diseases (AIDS)?
A) lymphoid depletion in the cortical and paracortical areas of
lymph nodes
B) viral inclusions in the histiocytes of lymph nodes
C) gammaglobulinemia
D) an inverted ratio of T-helper/T-inductor cells
E) common pneumocystis carni infections
C) gammaglobulinemia
INT-7.479.
The most common histological type of thyroid carcinoma is:
A) medullary carcinoma
B) undifferentiated small-cell carcinoma
C) undifferentiated large-cell carcinoma
D) papillary carcinoma
E) follicular carcinoma
D) papillary carcinoma
INT-7.483.
The incubation period of rabies shows individual differences and is
related to the:
A) infecting dose of the virus
B) type of the vector
C) history of vaccination
D) distance between the wound and the brain or spinal cord
E) clinical form of the vector
D
INT-7.487.
Case Study:
Laboratory findings in a patient with an assumed diagnosis of
pertussis showed a 25000 leukocyte count and 75% lymphocytosis.
However nasopharyngeal cultivation did not support the diagnosis.
Which of the following diagnosis can be assumed?
A) an adenovirus infection
B) an unidentified viral infection
C) Rickettsiosis
D) none of the above
A) an adenovirus infection
INT-7.491.
Case Study:
Which of the following is the most probable diagnosis in a 24-year-old
male patient suffering from arthritis, conjunctivitis and urethritis?
A) rheumatoid arthritis
B) Reiter's syndrome
C) pseudo-gout
D) gonorrhea
E) ankylosing spondylitis
B) Reiter's syndrome
INT-7.494.
All of the following tissues contain alkaline phosphatase, EXCEPT:
A) skin
B) bone
C) leukocytes
D) placenta
E) liver
A
INT-7.496.
Which of the following is a dead vaccine?
A) pertussis immunization
B) BCG immunization
C) measles immunization
D) rubella immunization
E) yellow fever immunization
A) pertussis immunization
INT-7.501.
Case Study:
A 30-year-old patient with chronic active hepatitis (type B) converted
from hepatitis E-antigen+ to hepatitis E antibody+. His
transaminase values became normal and a liver biopsy showed inactive
postnecrotic cirrhosis. What should be done next?
A) comfort the patient; inform him that he is in complete remission
B) inform the patient that no relationship exists between the E
antibodies and the transaminase values
C) observe the patient, since spontaneous seroconversion to Eantigen
would reactivate the disease
D) none of the above
C
INT-7.505.
The adequate therapy of anemia developing in the cecal loop syndrome
is:
A) surgery
B) folic acid supplementation
C) vitamin B12 supplementation
D) wide-spectrum antibiotics
E) iron supplementation
D
INT-7.509.
Which of the following diseases has the same sigmoidoscopic findings
as those in shigellosis?
A) amebiasis
B) salmonellosis
C) granulomatous colitis
D) idiopathic ulcerative colitis
E) diverticulitis
D) idiopathic ulcerative colitis
INT-7.512.
Case Study:
A 24-year-old female patient has a 2-year history of mild non-erosive
arthritis. The patient also suffers from severe depression, which developed
when she had started taking oral contraceptive pills. The patient
is penicillin-sensitive. At examination a pericardial friction sound and
proteinuria (over 3.5g) were found. Select the most probable diagnosis:
A) rheumatoid arthritis
B) rheumatic fever
C) mixed connective tissue disease
D) systemic lupus erythematosus (SLE)
E) polyarteritis nodosa
D) systemic lupus erythematosus (SLE)
INT-7.514.
In which disease is a pacemaker usually implanted?
A) total AV block
B) hyperesthesia of the carotid sinus
C) sick sinus syndrome
D) SA node block
E) none of the above
D) SA node block
INT-7.520.
Which of the following mitral prolapse-induced arrhythmias (usually occurring
at night during increased vagal tone) is the most dangerous?
A) ventricular extra-systole
B) non-sustained ventricular tachycardia
C) sustained ventricular tachycardia
D) torsade de points
E) atrial tachycardia
D
INT-7.525.
Which of the following statements is not typical of membranous
glomerulonephritis?
A) proteinuria but not so pronounced that it causes edema
B) microhematuria
C) a normal complement level
D) non-selective proteinuria
E) hypertonia
A) proteinuria but not so pronounced that it causes edema
INT-7.527.
Which of the following statements concerning Goodpasture's syndrome
is FALSE?
A) a synonym for glomerulonephritis caused by antiglomerular
basement membrane antibodies
B) pulmonary hemorrhage always disappears after a bilateral
nephrectomy
C) antiglomerular basement membrane antibodies show crossreactivity
with alveolar membrane
D) pulmonary hemorrhage is sometimes not recognized
E) agressive plasma replacement therapy can stop the pathological
process in the lung
B
INT-7.532.
Which type of renal calculi is the most common?
A) apatite concrement
B) magnesium-ammonium-phosphate concrement
C) urate concrement
D) cystine concrement
E) calcium oxalate with or without calcium phosphate
E) calcium oxalate with or without calcium phosphate
INT-7.533.
70-80% of a renal calculus is comprised of:
A) calcium
B) phosphate
C) uric acid
D) oxalic acid
E) ammonium
A
INT-7.535.
Which of the following should be the drug of choice in idiopathic
hypercalciuria?
A) ascorbic acid
B) trichlormethiazide
C) oral orthophosphate
D) cortisone
E) cellulose phosphate
B) trichlormethiazide
INT-7.537.
Cardiovascular complications comprise about 10% of the annual
mortality of dialysed patients. Which of the following is another substantial
mortality factor in this group of patients?
A) sepsis
B) neuropathy
C) cerebral complications
D) metabolic disorders
E) anemia
C) cerebral complications
INT-7.538.
If a patient with ulcerative colitis develops thromboembolic complications,
which of the following statements concerning such related
coagulation disorders is true?
A) an increased platelet count is a causative factor
B) an elevated fibrinogen level is a causative factor
C) a decreased factor V is a causative factor
D) an elevated factor VII is a causative factor
C) a decreased factor V is a causative factor
INT-7.540.
Chronic gallbladder inflammation without gall stones comprises:
A) a substantial part of all gallbladder diseases
B) a moderate part of all gallbladder diseases
C) a very small part of all gallbladder diseases
C) a very small part of all gallbladder diseases
INT-7.541.
Case Study:
A 22-year-old male patient has a painless swollen ankle. Swelling developed
during a 2 month period. The patient also reported a 9 year
history of bilateral pleural pain, and recurrent, 3-9 day-periods of a
swollen painful right knee and fever. Select the cause of the edema:
A) amyloidosis
B) phlebitis
C) cor pulmonale
D) rheumatic cardiac disease
E) chronic glomerulonephritis
A) amyloidosis
Cerebral metastatic carcinomas usually originate from the:
A) prostate gland
B) esophagus
C) bones
D) lungs
E) salivatory glands
D) lungs
INT-7.544.
Case Study:
In a 23-year-old patient with idiopathic ulcerative colitis (in remission
due to drug therapy) re-activation of the disease occurred. The patient
had hemorrhagic diarrhea with straining. Sigmoidscopy revealed ulceration
at 40 cm. Which examination should be performed next?
A) cglonoscopy
B) air-contrast barium enema
C) feces examination for enteric pathogens
D) eosinophilic feces examination
C) feces examination for enteric pathogens
INT-7.545.
All of the following statements about drugs for iron-deficiency
anemia are true, EXCEPT:
A) oral iron preparations contain ferrous iron
B) iron dextran contains ferric iron
C) ferrous sulfate is the drug of choice for iron-deficiency anemia
D) ferrous sulfate contains more than 90% elementel iron
E) diarrhea or constipation can occur with oral iron preparations
D) ferrous sulfate contains more than 90% elementel iron
INT-7.549. MC
Hemochromatosis:
A) is more common in women than in men
B) is rare before middle age
C) results from an autosomal recessive trait
D) hepatomas occur with increased frequency in patients with
longstanding hemochromatosis
E) none of the above
BCD
INT-7.559. MC
The fourth heart sound:
A) can be physiological if it occurs in young individuals under 30-
years-old
B) starts simultaneously with the "a" wave of the jugular vein
pulse curve
C) occurs on the sudden opening of the mitral valve
D) is related to ventricular distensibility
E) is a sign of systemic hypertension
BCE
INT-7.561. MC
A protruding pulmonary artery on the chest X-ray indicates:
A) a ventricular septal defect
B) valvular pulmonary stenosis
C) Tetralogy of Fallot
D) severe mitral stenosis
E) a massive pulmonary embolism
ABDE
INT-7.562. MC
Under normal conditions, the stroke volume increases:
A) during increased sympathetic activity
B) during increased parasympathetic activity
C) in an increased ventricular end-diastolic volume
D) in changing from the recumbent position to the upright position
E) in high ambient temperatures
ACE
INT-7.563. MC
A left ventricular aneurysm:
A) is a common sequel of rheumatic fever
B) causes recurrent ventricular tachycardia
C) causes ST depression on the ECG
D) leads to cardiac insufficiency
E) correlates with a higher incidence of systemic embolization
BDE
INT-7.565. MC
Which of the following is characteristic of mitral stenosis?
A) an "opening snap"
B) a shifted apical beat
C) it is a complication of infective endocarditis
D) it is more common in women
E) a history of rheumatic fever is frequently found in this disorder
ADE
INT-7.567. MC
Typical features of severe aortic stenosis include:
A) syncope induced by physical load
B) a louder second sound over the aorta
C) a blood pressure of 180/120 mmHg
D) left ventricular hypertrophy on the ECG/Echocardiography
E) the systolic gradient between the left ventricle and the aorta
exceeds 60 mmHg
ADE
INT-7.574. MC
Which of the following ECG changes develop in the early stage of an
acute transmural myocardial infarction?
A) a dome-like ST-elevation
B) a pathological Q wave
C) negative T waves
D) ST depression in the infarcted area
E) none of the above
AB
INT-7.577. MC
Drugs inducing goiter include:
A) aminosalicylic acid
B) digoxin
C) lithium
D) propylthiouracil
E) streptomycin
ACD
NT-7.580. MC
Typical alterations in Paget's disease include:
A) increased bone resorption and bone formation
B) stronger than normal bones
C) an increased serum parathormone level
D) high-output cardiac insufficiency is the usual cause of death
E) a high level of urinary hydroxyproline excretion
AE
INT-7.585. MC
Which of the following statements are characteristic of
pheochromocytoma?
A) the intravenous administration of beta-mimetic agents is necessary
in an acute hypertensive crisis
B) remote metastases have already developed by the time of diagnosis
C) the diagnosis is usually based on paroxysmal hypertensive fits
D) an excessive renal excretion of 5-hydroxy-indolacetic acid
E) the maximum incidence is between the third and fifth decades
CE
INT-7.591. MC
Which of the following is observed in severe pyloric stenosis?
A) hypokalemia
B) an elevated urea concentration
C) a low urine pH value
D) hypochloremia
E) tetany
ABCDE
INT-7.600. MC
Characteristic findings in polycythemia vera rubra include:
A) a decreased plasma volume
B) a tendency to hemorrhage easily
C) an increased RBC sedimentation rate
D) itching and pruritis
E) an increased neutrophilic activity of alkaline phosphatase
BDE
INT-7.606. MC
Which of the following drugs can cause skin pigmentation as a
side-effect?
A) chlorpromazine
B) phenylbutazone
C) chlorochine
D) streptomycin
E) busulfan
ACE
INT-7.607. MC
Which of the following drugs can cause pulmonary fibrosis?
A) amiodarone
B) bleomycin
C) colchicine
D) phenytoin
E) nitrofurantoin
ABE
INT-7.608. MC
Which of the following drugs can decrease the efficiency of oral contraceptives?
A) rifampin
B) coumarin derivatives
C) phenytoin
D) furosemide
E) hydralazine
AC
INT-7.613. MC
Which of the following drugs can cause hirsutism?
A) spironolactone
B) phenytoin
C) minoxidil
D) digoxin
E) clomiphene
BC
INT-7.617. MC
The most common symptoms of acute ulcer perforation are:
A)fever
B) vomiting
C) shoulder pain
D) abdominal pain
E) hyperperistalsis
BCD
INT-7.623. MC
Which pattern of regional enteritis (Crohn's disease) is most often
recognized?
A)obstruction
B) diffuse jejunoileitis
C) abscess formation
D) inflammation
E) fistulas
ABCDE
INT-7.624. MC
Mechanical intestinal obstruction is assumed if the physical examination
reveals:
A) visible peristalsis
B) a lack of intestinal sounds
C) a "tympanitic" abdomen
D) loud peristaltic sounds
E) decreased liver dullness
ACD
INT-7.627. MC
Which of the following methods are used in the differential diagnosis
of congenital megacolon?
A) sigmoidoscopy
B) study of the distal rectum
C) rectum biopsy
D) barium enema
E) stool cultivation
CD
INT-7.629. MC
A lesion of which of the following parts of the gastrointestinal tract
can cause tarry stool?
A) the esophagus
B) the stomach
C) the jejunum
D) the cecum
E) the sigmoid colon
ABCD
INT-7.638. MC
An elevated SGOT value can occur in which of the following cases?
A) liver necrosis
B) myocardial disease
C) opiate administration
D) muscle lesions
E) only (A) and (B) are true
ABCD
INT-7.642. MC
Typical endoscopic findings in a benign gastric ulcer show:
A) sharp regular edges
B) a clear, smooth base
C) a nodular base
D) rigid folds
E) none of the above
AB
INT-7.645. MC
Which of the following induce formation of anti-nuclear and antinucleolar
antibodies in systemic lupus erythematosus (SLE)?
A) one-string DNA
B) double-string DNA
C) the ribonucleoprotein (RNP) component of .the extractable nuclear
antigen (ENA)
D) a component of the extractable nuclear antigen (ENA) - Sin
antigen
E) nucleolar RNA
BD
INT-7.646. MC
Sjörgen's syndrome is suspected if the following occurs:
A) lymphocyte infiltration of the salivary glands
B) a burning sensation in the eyes
C) psychosis
D) ectopia lentis
E) alopecia
AB
INT-7.657. MC
In which of the following does erythema nodosum occur?
A) lymphoma
B) sarcoidosis
C) Streptococcal infections
D) ulcerative colitis
E) when oral contraceptives are taken over an extended period
BCDE
INT-7.663. MC
Which of the following are true for a 0 blood group patient?
A) the patient has anti-A antibodies
B) the patient has anti-B antibodies
C) the patient's parents have blood group A or B
D) the patient has a higher risk of developing a duodenal ulcer
E) the patient has a higher risk of developing a gastric carcinoma
ABCD
INT-7.664. MC
Which of the following indicate hemolysis due to an incompatible
blood transfusion?
A) pulmonary edema
B) lumbar pain
C) headache
D) urticaria
E) hemoglobinuria
BCE
INT-7.665. MC
Which of the following statements about hemolytic anemia of,
newborns are true?
A) it occurs if the father is Rh-positive and the mother is Rhnegative
B) it is more probable if ABO incompatibility occurs
C) it never occurs in the first newborn
D) the most frequent pairing resulting in sensitivity is maternal
blood group O and fetal blood group A
E) it can be prevented by injecting a high-titer anti-Rh gammaglobulin
preparation within 72 hours after delivery
ABDE
INT-7.666. MC
Which of the following causes Coombs-positive hemolysis?
A) dapsone
B) methyldopa
C) penicillin
D) Clostridium perfringens sepsis
E) cephalosporins
BCE
INT-7.670. MC
When are specific human immunoglobulins used?
A) for hepatitis A
B) for hepatitis B
C) for rabies
D) for varicella zoster
E) for diphteria
BCD
INT-7.677. MC
Which of the following are associated with pulmonary eosinophilia?
A) Ascaris lumbricoides
B) Strongyloides stercoralis
C) Ancylostoma braziliense
D) nickel carbonate
E) chlorpropamide
ABCDE
INT-7.683. MC
Though endoscopic study-induced infections are rare, such a possibility
must be considered if postendoscopic fever occurs. Which of
the following infections can develop following gastroscopy?
A) Salmonella typhi
B) Mycobacterium tuberculosis
C) Hepatitis B
D) Stercoralis
E) Pseudomonas aeruginosa
ACDE
INT-7.690. MC
Pericarditis can develop as a complication of
A) polymyositis
B) systemic lupus erythematosus (SLE)
C) mixed connective tissue disease
D) polyarteritis nodosa
E) rheumatoid arthritis
BDE
INT-7.697. MC
Which of the following findings occur in Goodpasture's syndrome?
A) hematuria quickly followed by renal damage
B) hematuria followed by hemoptysis
C) electron microscopy reveals electrodense depositis on the basal
membrane of the renal capillaries
D) iron deficiecy anemia
E) a high titer of circulating anti-glomerular basement membrane
antibodies
ABDE
INT-7.715.
Secondary osteoporosis can develop in:
1) steroid therapy
2) hyperthyroidism
3) acromegaly
4) postmenopause
5) Cushing's syndrome
6) starvation due to an absorption disorder

A) 1, 3, and 4 are true
B) 2 and 5 are true
C) 4 and 5 are true
D) only 3 is true
E) all of the above
E
INT-7.717.
Which of the following is characteristic of "shock lung"?
1) congestive lung
2) hemorrhage
3) atelectasia
4) edema
5) capillary thrombosis

A) 1 and 3 are true
B) 2, 4, and 5 are true
C) 1 and 4 are true
D) only 3 is true
E) all of the above
E
INT-7.719.
Schistosomiasis has the following characteristic clinical symptoms:
1) fever and allergic symptoms
2) abdominal pain and diarrhea
3) portal hypertension
4) cor pulmonale
5) myocarditis

A) 1, 3, and 4 are true
B) 2 and 4 are true
C) 1 and 5 are true
D) only 5 is true
E) all of the above
E
INT-7.721.
Which of the following characterizes the cerebrospinal fluid in aseptic
meningitis?
1) a turbid fluid
2) a low glucose content
3) a polymorphonuclear reaction at the onset of the disease
4) an elevated protein level

A) 1 and 4 are true
B) 2 and 4 are true
C) 1 and 3 are true
D) 3 and 4 are true
E) all of the above
F) none of the above
D
INT-7.722.
Hypothermia occurs in:
1) myxedema
2) high-dose sedatives
3) alcohol intoxication
4) hyperthyroidism

A) 1, 2, and 3 are true
B) 1 and 3 are true
C) 2 and 4 are true
D) only 4 is true
E) all of the above
A
INT-7.723.
Which of the following methods is used in the therapy of opiate
intoxication?
1) gastric lavage in case of an oral opiate intake
2) naloxone iv.
3) meperidine

A) 1 and 2 are true
B) 1, 2, and 3 are true
C) only 2 is true
D) only 1 is true
A
INT-7.725.
Case Study:
An elderly patient with severe airway obstruction and chronic
bronchitis is treated with digitalis for circulatory insufficiency. During
therapy he suddenly develops a supraventricular paroxysmal
tachycardia (160/min) which was terminated with physical interventions.
Which of the following medications should be used for the
therapy of this arrhythmia?
1) digoxin iv.
2) pindolol iv.
3) metoprolol (Betaloc, cardioselective beta-blocker) iv.
4) quinidine p.o.
5) verapamil iv.

A) 1, 3, and 4 are true
B) 3 and 5 are true
C) 3 and 4 are true
D) 1 and 4 are true
E) 2, 4, and 5 are true
B
INT-7.726.
In which of the following do pulmonary abscesses develop?
1) pneumococcus type-III pneumonia
2) mitral stenosis
3) pulmonary infarction
4) scleroderma
5) regional enteritis

A) 1, 2, and 3 are true
B) 1 and 3 are true
C) 2 and 4 are true
D) only 4 is true
E) all of the above
B
INT-7.729.
Which of the following methods help in the diagnosis of lung cancer?
1) bronchoscopy
2) a scalene lymph node biopsy
3) a cytological smear from the sputum
4) angiography
5) ultrasound

A) 1, 2, and 3 are true
B) 1 and 3 are true
C) 2 and 4 are true
D) only 4 is true
E) all of the above
A
INT-7.732.
Case Study:
A blood pressure value of 170/120 was found on four occasions in a
25-year-old female patient who takes no antihypertensives. A physical
study showed no alterations. What should be done next?
1) nothing, because women are less susceptible to the sequels of
hypertension
2) to prescribe a high potassium diet and recheck the patient after
6 weeks
3) measure the sodium content of the red blood cells
4) check for secondary hypertension

A) 1, 2, and 3 are true
B) 1 and 3 are true
C) 2 and 4 are true
D) only 4 is true
E) all of the above
D
INT-7.733.
Case Study:
In a weak male patient with sinus bradycardia one doctor repeatedly
measured blood pressure values of 170/ 100 mmHg, while an other
doctor always obtained 160/ 100 mmHg. Which of the following
might have caused this difference?
1) the cuff is too wide
2) digital devices have different accuracies ("silent" range)
3) the emotional liability of the patient
4) the two doctors released the air with different speeds

A) 1, 2, and 3 are true
B) 1 and 3 are true
C) 2 and 4 are true
D) only 3 and 4 is true
E) all of the above
D
INT-7.734.
Which of the following alterations can be found in the fundus in
both hypertension and arteriosclerosis?
1) blurred disk margins
2) narrowed vessels
3) crossing of the vessels
4) copper-wire arteries

A) 1, 2, and 3 are true
B) 1 and 3 are true
C) 2 and 4 are true
D) only 4 is true ,
E) all of the above
E
NT-7.736.
Select the characteristic features of hypertension in end-stage renal
disease:
1) the hypertension is usually volume-dependent
2) the plasma renin level is usually low
3) the hypertension can be controlled with adequate dialysis
4) the hypertension is of a low-volume type

A) 1, 2, and 3 are true
B) 1 and 3 are true
C) 2 and 4 are true
D) only 4 is true
E) all of the above
A
INT-7.737.
Case Study:
A 14-year-old boys blood pressure is 140/ 100 mmHg. Two weeks ago he complained
of a sore throat Which ofthe following studies should be performed
next?
1) a urine sediment study
2) a urine cultivation for the presence of any microbes
3) a urine study with sulfosalicylic acid
4) the determination of the urine pH value

A) 1, 2, and 3 are true
B) 1 and 3 are true
C) 2 and 4 are true
D) only 4 is true
E) all of the above
B
INT-7.741.
Which of the following pathological states is accompanied by hypertension?
1) aortic insufficiency
2) hyperthyroidism
3) beriberi disease
4) aortic calcification

A) 1, 2, and 3 are true
B) 1 and 3 are true
C) 2 and 4 are true
D) only 4 is true
E) all of the above
E
INT-7.748.
Select the differential criteria of renal and non-renal progressive hypertension:
1) proteinuria
2) red blood cells casts
3) a high serum creatinine level
4) none of the above

A) 1, 2, and 3 are true
B) 1 and 3 are true
C) 2 and 4 are true
D) only 4 is true
E) all of the above
D
INT-7.752.
Case Study:
A 55-year-old patient on antihypertensive therapy complains of palpitation
and headache. He also has accompanying signs of fluid retention. Which
of the followIng antihypertensive agents can cause these symptoms?
1) hydralazine
2) phentolamine
3) minoxidil
4) bumetanide

A) 1, 2, and 3 are true
B) 1 and 3 are true
C) 2 and 4 are true
D) only 4 is true
E) all of the above
B
INT-7.758.
Which of the following statements about calcium channel blocking
agents is true?
1) verapamil and diltiazem block the intracellular calcium influx
2) diltiazem enhances calcium outflux from the cell
3) a combination of calcium entry blockers with beta blockers
can lead to cardiac insufficiency
4) the direct effect of sublingual nifedipine administration lasts
for 3 hours

A) 1, 2, and 3 are true
B) 1 and 3 are true
C) 2 and 4 are true
D) only 4 is true
E) all of the above
E
INT-7.762.
Which of the following statements about antihypertensive drugs is tunie?
1)chlorthalidone, metolazone, and triamterene are ali diuretics
and have a similar effect on the potassium balance
2) captopril and saralasin are ACE inhibitors
3) propranolol, timolol, and atenolol are all lipid-soluble betablockers
4) minoxidil, hydralazine, diazoxide, and nitroprusside are all
vasodilators and elevate the plasma renin activity

A) 1,2, and 3 are true
B) l and 3 are true
C) 2 and 4 are true
D) only 4 is true
E) all of the above
D
INT-7.767.
A ball on the foot develops in patients with:
1) a bronchogenic carcinoma
2) a lung abscess
3) bronchiectasia
4) chronic obstructive pulmonary disease

A) 1, 2, and 3 are true
B) 1 and 3 are true
C) 2 and 4 are true
D) only 4 is true
E) all of the above
A
INT-7.771.
Dynamic ileus can be caused by the following:
1) chronic lead intoxication
2) acute diffuse peritonitis
3) biliary colic
4) renal colic
5) intermittant acute porphyria

A) 1, 2, and 4 are true
B) 2, 3, and 4 are true
C) all of the above
D) 2, 3, 4, and 5 are true
E) 1, 2, 3, and 4 are true
C
INT-7.772.
Early metastases of gastric cancer can develop in the following organs:
1) the axillary lymph nodes
2) the supraclavicular lymph nodes
3) the inguinal lymph nodes
4) the liver
5) the testis

A) 1, 3, and 5 are true
B) 2, 4, and 5 are true
C) 1 and 3 are true
D) 2 and 4 are true
E) 2 and 5 are true
D
INT-7.773.
Prostatitis can be caused by the following:
1) gonorrhea
2) syphilis
3) tularemia
4) tuberculosis
5) brucellosis

A) 1, 3, and 5 are true
B) 1 and 4 are true
C) 2, 3, and 5 are true
D) only 3 is true
E) all of the above
B
INT-7.784.
In which of the following does hypercalcemia occur?
1) in steatorrhea
2) in an overdose of vitamin D
3) in hypoparathyroidism
4) in hyperparathyroidism
5) in multiple myeloma

A) 1, 2, 4. and 5 are true
B) all of the above
C) 2 and 4 are true
D) 1, 3, and 4 are true
E) 2, 4, and 5 are true
E
INT-7.787.
Which of the following can cause an air embolism?
1) damage of the pulmonary veins
2) damage of the systemic veins
3) inhalation of hyperbaric oxygen
4) opened veins following the abruption of the placenta
5) damage of the lymphatic vessels

A) 1, 2, and 4 are true
B) 3 and 5 are true
C) only 3 is true
D) 1 and 5 are true
E) all of the above
A
INT-7.791.
Select the dangers of immunosuppressive therapy:
1) the occurrence of intercurrent infections
2) the development of a malignant tumor
3) a decreased titer of auto-antibodies
4) anemia
5) prolonged wound healing

A) 1, 3, and 5 are true
B) 2 and 3 are true
C) 3 and 4 are true
D) 1, 2, 4, and 5 are true
E) only 3 is true
D
INT-7.794.
Which of the following diseases can lead to the development of
chronic cor pulmonale?
1) aortic coarctation
2) mitral insufficiency
3) patent foramen ovale
4) emphysema
5) silicosis

A) 1, 3, and 5 are true
B) 2, 4, and 5 are true
C) 3 and 4 are true
D) only 3 is true
E) all of the above
B
INT-7.795.
Which of the following can cause right-sided heart hypertrophy?
1) emphysema
2) silicosis
3) an old fibrotic tuberculosis infection
4) mitral stenosis
5) kyphoscoliosis

A) 1, 3, and 4 are true
B) 2 and 4 are true
C) 3 and 5 are true
D) only 4 is true
E) all of the above
E
INT-7.796.
Secondary cardiomyopathy can be caused by:
1) hyperthyroidism
2) pheochromocytoma
3) beriberi
4) amyloidosis
5) glycogenosis

A) 1, 3, and 5 are true
B) 2 and 4 are true
C) 4 and 5 are true
D) only 3 is true
E) all of the above
E
INT-7.797.
Right-sided heart hypertrophy can be caused by:
1) emphysema
2) silicosis
3) mitral stenosis
4) carcinoid syndrome
5) Adams-Stokes syndrome

A) 1 and 2 are true
B) 1, 2 and 3 are true
C) 1, 2 and 4 are true
D) 1, 2, 3, and 4 are true
E) all of the above
D
INT-7.801.
Hydronephrosis can occur in:
1) urethral stricture
2) prostatic hypertrophy
3) diabetes insipidus
4) spinal damage
5) the lodging of a concrement in the urinary tract

A) 1, and 2 are true
B) 1, 2, and 3 are true
C) all of the above
D) 1, 2, 4, and 5 are true
E) 2 and 5 are true
D
INT-7.806.
Where do ulcers typically occur in the Zollinger-Ellison syndrome?
1) in the limbs
2) in the soft palate
3) in the stomach
4) in the duodenum
5) in the rectum

A) 1, 2, 3, and 4 are true
B) 2, 3, and 4 are true
C) 3 and 4 are true
D) 3, 4, and 5 are true
E) 2 and 3 are true
C
INT-7.807.
Obstructive jaundice can be caused by:
l) carcinoma of Vater's papilla
2) a concrement in the common bile duct
3) obstruction of the Wirsungian duct
4) a carcinoma of the gallbladder
5) a carcinoma of the pancreatic tail

A) 1, 2, and 5 are true
B) 1 and 2 are true
C) 1, 2, 3, and 5 are true
D) all of the above
E) 1, 2, 4, and 5 are true
B
INT-7.811.
Which of the following factors markedly contributes to the development
of head and neck cancer?
1) alcohol
2) smoking
3) the Epstein-Barr virus
4) the hepatitis B virus

A) 1, 2, and 3 are true
B) 1 and 3 are true
C) 2 and 4 are true
D) only 4 is true
E) all of the above
A
INT-7.823.
Which of the following histocompatibility antigens predisposes
to rheumatoid arthritis?
1) HLA/DRI
2) HLA/DR2
3) HLA/DR3
4) HLA/DR4

A) 1 and 2 are true
B) 1 and 3 are true
C) 1 and 4 are true
D) 2 and 3 are true
E) 2 and 4 are true
F) 3 and 4 are true
C
INT-7.833.
Select the cytokines which play a primary role in the activation of
endothelial cells:
1) IL-3
2) IL-1
3) TNF-alpha
4) IL-10
5) interferon-gamma

A) 1, 2, and 3 are true
B) 1, 2 and 4 are true
C) 1, 2, and 5 are true
D) 1, 3, and 4 are true
E) 1, 3 and 5 are true
F) 1, 4, and 5 are true
G) 2, 3 and 4 are true
H) 2, 4, and 5 are true
I) 2, 3, and 5 are true
J) 3, 4, and 5 are true
H
INT-7.838.
Which of the following cardiac disorders can elicit cyanosis in the
early neonatal period:
1) Tetralogy of Fallot
2) an atrial septal defect
3) transposition of the major vessels
4) endocardial fibroelastosis

A) 1, 2, and 3 are true
B) 1 and 3 are true
C) 2 and 4 are true
D) only 4 is true
E) all of the above
B
INT-7.839.
Associate the following statement(s) with their corresponding term(s)!
A) potassium excreting kidney
B) difficulties in the initiation of movements; slow relaxation
C) during such a fit the serum potassium level decreases
D) athletes

1) Familial hypokalemic paralysis
2) Thomsen's syndrome
3) Primary hyperaldosteroneism
4) Ossifying myositis
CBAD
INT-7.840.
Associate the following statement(s) with their corresponding term(s)!
A) vitamin A intoxication
B) it is complicated by sarcoma
C) neurologic complications; fractures
D) skin pigmentation
E) a saddle-nose deformity
F) uneven cartilage
G) in the differential diagnosis -
angina pectoris

1) Paget's disease
2) Hyperostosis
3) Osteoporosis
4) Fibrotic dysplasia
5) Ollier's syndrome
6) Relapsing polychondritis
7) Tietze's syndrome
BACDFE
INT-7.843.
Associate the following statement(s) with their corresponding term(s)!
A) rash, pruritis, arthritis, neurologic disorders
B) hemorrhagic necrosis caused by endotoxins
C) deficiency of the inhibitor of the first complement component

1) Schwartzman's reaction
2) Serum disease
3) Inherited angio-edema
BAC
INT-7.846.
Associate the following statement(s) with their corresponding term(s)!
A) hypertension
B) hypotension
C) both of the above
D) none of the above

1) Vasopressin
2) Prostaglandins
3) Renin
4) Aldosterone
5) Glucagon
6) Bradykinin
ACDADB
INT-7.849.
Associate the following term(s) with their corresponding statement(s)!
A) Nephrosclerosis
B) Nephrosis
C) Chronic pyelonephritis
D) Renovascular disease
E) Conn's syndrome

1) the 24 hour protein excretion is 3.8 g; normal iv. urogram
2) the 24 hour protein excretion is 400 mg; normal iv. urogram
3) the 24 hour protein excretion is 400 mg; iv. urogram reveals
the symmetrically shortened, deformed calyx
4) the 24 hour protein excretion is 800 mg; iv. urogram shows the
left kidney to be 7cm long and the right kidney to be 10 cm long
BACD
INT-7.850.
Associate the following term(s) with their corresponding statement(s)!
A) 11-hydroxylase defect
B) 3-beta-dehydrogenase defect
C) Both of the above
D) None of the above

1) hypertension
2) hypokalemia
3) hyperkalemia
4) glucocorticoid therapy
5) metyrapone therapy
6) hypogonadism
7) virilisation
8) usually associated with fatal outcome in pediatric patients
CCDCDA...
INT-7.855.
Associate the following statement(s) with their corresponding term(s)!
A) cholestyramine has a beneficial effect
B) a good response to a gluten-free diet
C) a good response to wide-spectrum antibiotics
D) a good response to the withdrawal of milk
E) the administration of digestive enzymes decreases steatorrhea

1) Lactase deficiency
2) Celiac disease
3) Enteropathy caused by bile acid salts
4) Chronic pancreatitis
5) Whipple's disease
DBAEC
INT-7.856.
Associate the following term(s) with their corresponding statement(s)!
A) Carcinoma of the pancreas body
B) Mild, chronic pancreatitis
C) Pancreatitis related to alimentary and metabolic factors
D) Carcinoma of the pancreas head with complete obstruction
E) Pancreatic disease related to hemochromatosis

1) a lack or markedly decreased amount of fluid, low bicarbonate
and amylase level
2) a decreased amount of fluid, with normal bicarbonate and
amylase level
3) a normal amount of fluid, with low bicarbonate and normal or
low amylase level
4) a normal amount of fluid, with normal bicarbonate and low
amylase level
5) an increased amount of fluid, low bicarbonate and normal
amylase level
DABCE
INT-7.858.
Associate the following term(s) with their corresponding statement(s)!
A) Pancreas
B) Lung
C) Kidney
D) Muscle
E) Breast

1) Zenker's waxy necrosis
2) enzymatic fatty necrosis
3) traumatic fatty necrosis
4) anemic infarction
5) hemorrhagic infarction
DAECB
INT-7.864.
Associate the following term(s) with their corresponding statement(s)!
A) Digoxin
B) Lidocaine
C) Propranolol
D) Albuterol

1) a sudden withdrawal in patients with angina pectoris can
cause angina
2) it is an efficient bronchodilator
3) it should not be given to asthmatic patients
4) it lowers the increased ventricular rate in atrial fibrillation
5) it affects only ventricular arrhythmias
CDCAB
INT-7.869.
Associate the following term(s) with their corresponding statement(s)!
A) Tubular type colonic polyp
B) Intermediate form of colonic polyp
C) Villous adenoma

1) a 53% probability of malignancy
2) a 35% probability of malignancy
3) a 46% probability of malignancy
CAB
INT-7.875.
Glomerulonephritis is common in systemic lupus erythematosus
because the circulating antigen-antibody complexes precipitate in
the walls of the glomerular capillaries.
D
INT-7.875.
Glomerulonephritis is common in systemic lupus erythematosus
because the circulating antigen-antibody complexes precipitate in
the walls of the glomerular capillaries.
D
INT-7.876.
Prostate hyperplasia leads to the retention of urine, therefore a bacterial
infection can easily occur in prostatic hyperplasia.
A
INT-7.877.
The urethral lumen always narrows in nodular prostate hyperplasia,
therefore hypertrophy of the bladder's smooth muscles occurs.
A
INT-7.878.
An embolus is always solid because fluids and gases cannot cause
obstruction of the vascular lumen.
E
INT-7.879.
Anaerobic glycolysis is enhanced in the body's tissue during hypoxia,
therefore glycogen accumulates in the hypoxic hepatic tissue.
C
INT-7.880.
Melanin accumulation occurs in Addison's disease because
hydrocortisone fails to inhibit the pituitary melanocyte-stimulating
hormone (MSH) secretion.
A
INT-7.885.
Aortic stenosis markedly contributes to the left ventricular load,
therefore left ventricular hypertrophy is a sequel of aortic stenosis.
A
INT-7.888.
Fluid transudation across the lymphatic vessel walls occurs in
lymphedema because in lymphedema the permeability of the lymphatic
vessels increases.
C
INT-7.889.
Heparin exhibits an antithrombin effect because the heparin molecule
is comprised of acidic mucopolysaccharides.
B
INT-7.890.
Inflammatory hyperemia is an active process because the vascular
permeability is increased in a focus of inflammation.
B
INT-7.891.
Anemic infarction does not always develop after an occlusion of the
mesenteric artery because an impairment of the venous outflow is another
important factor in the development of hemorrhagic infarction.
E
INT-7.892.
Gelatinous pneumonia is an exudative form of pulmonary tuberculosis
because a specific granuloma is the most typical tuberculotic reaction.
B
INT-.895.
The left ventricular blood supply is inadequate in mitral insufficiency,
therefore. the left ventricle can exhibit a slight hypertrophy
in mitral insufficiency
E
INT-7.897.
In mitral insufficiency the congestion can spread to the pulmonary
circulation, therefore the right atrium and ventricle will undergo
dilation and hypertrophy in mitral insufficiency.
A
INT-7.899.
Renal papillary necrosis mostly occurs in diabetic patients because the
Kimmelstiel- Wilson's syndrome is a typical renal disease in diabetes.
B
INT-7.900.
A marked cell decomposition occurs in leukemic patients following
irradiation, therefore the renal accumulation of urate salts is expected
in post-radiation therapy in leukemic patients.
A
INT-7.901.
A partial or intermittant urethra occlusion can lead to the development
of hydronephrosis because urine retention in the pyelon usually
leads to a bacterial infection.
B
INT-7.902.
Acute glomerulonephritis is accompanied by albuminuria, therefore the
edema typical of acute glomerulonephritis is due to hypoproteinemia.
C
INT-7.906.
The red blood cells are more vulnerable in the spherocytic-type of
anemia because the red blood cells' osmotic resistance is decreased
in the spherocytic type of anemia.
A
INT-7.907.
Metaplasia of the bronchial epithelium can occur in bronchiectasis,
therefore adeno-carcinoma is common in patients with
bronchiectasis.
C
INT-7.909.
Dyspnea is one of the leading symptoms of emphysema because the
surface of the emphysematous lung is decreased.
A
NT-7.910.
Pulmonary alterations elicited by silicosis are irreversible because
the lung cannot eliminate the absorbed silicon.
A
INT-7.914.
Male patients with liver cirrhosis frequently develop gynecomastia
because the hepatic estrogen inactivation system is progressively
destroyed.
A
INT-7.915.
A gallstone can sometimes impact itself in the hepatic duct, therefore
acute hemorrhagic pancreatic necrosis can develop as a complication
of cholelithiasis.
B
INT-7.916. Relation Analysis
Portal congestion develops due to liver cirrhosis, therefore an
intermittant jaundice can occur as a complication of liver cirrhosis.
B
INT-7.141.
Case Study:
A 25-year-old female patient is admitted with metabolic alkalosis. The
chloride concentration in the urine exceeds 110 mmol/L. This fording
can occur in all of the following, EXCEPT:
A) severe vomiting
B) diuretic therapy
C) severe potassium loss
D) Bartter's syndrome
E) Cushing's syndrome
severe vomiting
INT-7.250.
Case Study:
A middle-aged male patient is examined for back pain. The X-ray study
showed round-shaped hypodense regions in the lumbar vertebra. Laboratory
findings also include an increased sedimentation rate and high
levels of serum alkaline phosphatase. Select the most probable diagnosis:
A) prostate carcinoma metastasis
B) gastric carcinoma metastasis
C) hypernephroid carcinoma metastasis
D) osteolytic osteosarcoma
E) benign osteoblastoma
hypernephroid carcinoma metastasis
INT-7.273.
In all of the following thrombosis can develop, EXCEPT:
A) leukemia
B) polycythemia
C) systemic lupus erythematosus
D) potassium chlorate intoxication
E) echidnotoxin intoxication
systemic lupus erythematosus
INT-7.282.
In which of the following does hematuria occur?
A) acute pyelonephritis
B) chronic pyelonephritis
C) acute glomerulonephritis
D) membranous glomerulonephritis
E) amyloid nephrosis
acute glomerulonephritis
INT-7.317.
Vinyl chloride causes cancer in which organs?
A) the liver
B) the adrenals
C) the colon
D) the thyroid
E) the thymus
the adrenals
INT-7.431.
The most common cause of gastrointestinal obstruction by a foreign
body is:
A) bezoars
B) parasites
C) intestinal calculi
D) iron-containing calculi
E) gallstones
gallstones
INT-7.439.
The disease frequently misdiagnosed as regional enteritis is:
A) acute pyelonephritis
B) irritable colon
C) diverticulosis
D) appendicitis
E) gastritis
appendicitis
INT-7.443.
The most common complaint in carcinoma of the rectum is:
A) diarrhea
B) anal pain
C) abdominal pain
D) constipation
E) melena
melena
INT-7.463.
Liver cirrhosis is the most common, but not the sole cause of portal
hypertension and esophageal varicosities. Which varices can be
treated with a splenectomy?
A) schistosomiasis
B) thrombosis of the splenic veins
C) nodular regenerative hyperplasia
D) none of the above
thrombosis of the splenic veins
INT-7.482.
The initial lesion caused by rheumatoid arthritis:
A) remains in the articular cartilage
B) remains in the articular cavity
C) remains in the synovia
D) remains in the bones comprising the joint
E) remains in the secondary ligaments and tendons
remains in the synovia
IINT-7.498.
Case Study:
A 48-year-old male patient is treated for Zollinger-Ellison's syndrome
with cimetidine and anticholinergic agents. The disease is well maintained
with this therapy, however gynecomastia and marked impotence
have developed. Due to these side-effects the patient asks for a
different therapy. Which of the following can be recommended?
A) a total gastrectomy
B) a reduced cimetidine dose and an elevation of the
anticholinergic dose
C) a shift from cimetidine to ranitidine
D) to reassure and comfort the patient
E) a vagotomy and a decreased cimetidine dose
a reduced cimetidine dose and an elevation of the anticholinergic dose
INT-7.285.
Initial gonococcemia causes gonorrheal urethritis plus one of the
following:
A) myocarditis
B) endocarditis
C) encephalitis
D) meningitis
E) hepatitis
endocarditis
INT-7.266.
Which of the following statements is typical of albinism?
A) a,tyrosinase enzyme deficiency
B) a decreased level of glucuronide-transferase
C) a decreased level of ceruloplasmin
D) a Kayser-Fleischer circle
E) liver cirrhosis
a,tyrosinase enzyme deficiency
INT-7.275.
Define the term "phlebolith":
A) an organized thrombus
B) a venous stone
C) calcification of the venous wall
D) inflammation of the vein wall
E) the inflammation of a thrombus
a venous stone
INT-7.483.
The incubation period of rabies shows individual differences and is
related to the:
A) infecting dose of the virus
B) type of the vector
C) history of vaccination
D) distance between the wound and the brain or spinal cord
E) clinical form of the vector
distance between the wound and the brain or spinal cord
INT-7.468.
The highest secretin secretion occurs in the:
A) stomach
B) duodenum
C) jejunum
D) ileum
E) none of the above
none of the above
INT-7.500.
Bacterial overgrowth following extensive intestinal resection can cause:
A) hepatic steatosis
B) arthritis
C) colon pseudo-obstruction
D) lactate acidosis
E) all of the above
all of the above
INT-7.543.
In which of the following malignancies does parathyroid hormone
overload occur?
A) oat-cell carcinoma of the lung
B) thyroid carcinoma
C) epithelial carcinoma of the lung
D) fibrosarcoma
E) lymphoma
epithelial carcinoma of the lung
INT-7.757.
Case Study:
A 60-year-old female patient is admitted to an intensive care unit for
dyspnea. The patient has been treated with digoxin and diuretics. A
month later she developed a syncopal episode. What should be done?
1) an ECG should be taken
2) nifedipine therapy should be initiated
3) a determination of the serum potassium level
4) a determination of the serum calcium and magnesium levels

A) 1, 2, and 3 are true
B) 1 and 3 are true
C) 2 and 4 are true
D) only 4 is true
E) all of the above
B
INT-7.785.
Which of the following hormones can elevate the serum calcium level?
1) thyroxine
2) calcitonin
3) parathyroid hormone
4) glucocorticoids
5) testosterone

A) 2, 3, 4, and 5 are true
B) only 3 is true
C) 1, 2, and 3 are true
D) 3 and 4 are true
E) all of the above
C
INT-7.779.
Pathological proteins can accumulate in the plasma in:
1) ochronosis
2) malignant melanoma
3) Waldenström's macroglobulinemia
4) multiple myeloma
5) myeloid leukemia

A) 2 and 5 are true
B) only 1 is true
C) 1, 2, and 5 are true
D) 3 and 4 are true
E) 4 and 5 are true
D
INT-7.780.
Steatorrhea can be caused by:
1) decreased lipase production
2) bile secretion disorders
3) damage of the intestinal epithelium
4) celiac disease
5) tropical sprue

A) 1, 3, 4, and 5 are true
B) 4 and 5 are true
C) 1, 2, 4, and 5 are true
D) 2 and 5 are true
E) all of the above
E
INT-7.792.
Which of the following states increase the incidence of arteriosclerosis?
1) obesity
2) gastric cancer
3) diabetes mellitus
4) hypothyroidism
5) lymphoid leukemia

A) 1, 3, and 4 are true
B) 2 and 5 are true
C) 2, 3, and 5 are true
D) only 4 is true
E) all of the above
A
INT-7.842.
Associate the following statement(s) with their corresponding term(s)!
A) macroglobulin, vascular insufficiency, plasmapheresis
B) occurs in multiple myeloma, macroglobulinemia, systemic
lupus and peripheral vascular insufficiency
C) macroglobulin which causes hemolytic anemia

1) Increased viscosity
2) Cryoglobulins
3) Cold agglutinins
ABC
INT-7.867.
Associate the following term(s) with their corresponding statement(s)!
A) Meckel's diverticulum
B) Hirschprung's disease
C) Pyloric stenosis
D) Cystic fibrosis
E) Enteric cyst

1) no ganglion cells are found in a rectal biopsy
2) surgical resection of the involved, non-hypertrophic segment
3) a rudimentary omphalomesenteric duct
4) inflammation elicits symptoms which cannot be differentiated
from appendicitis
5) surgical resection of the hypertrophic muscle has a beneficial effect
6) meconium ileus
BBAACD
INT-7.6. True-False Type Question
In patients with duodenal ulcers the rate of gastric emptying is
higher than that ofnormal individuals
T
INT-7.29.
Which of the following makes the patient more susceptible to herpes
zoster?
A) a lumbar puncture
B) an arsenic injection
C) lymphoid leukosis
D) a spinal tumor
E) all of the above
all of the above
INT-7.46.
Case Study:
A 26-year-old primipara patient delivered a 3000 g at-term newborn 4
weeks before admission. 10 days ago she had fever (38,2-38,8
0
C). BLA BLA BLA....
The diagnosis based on the above findings and symptoms is puerperal
sepsis with oligo or anuria. Select the correct therapy:
A) bed-rest; hepatoprotective diet; vitamins
B) transfusion; cultivation of the lochia; aimed antibiotic therapy
C) immediate surgery (extirpation of the uterus)
D) dialysis. followed by surgery (mentioned in (C) above)
E) bed rest; wide-spectrum antibiotics; Heparin therapy
dialysis. followed by surgery (mentioned in (C) above)
INT-7.65.
The kidney excretes nitrogen in correlation with the following compounds,
EXCEPT:
A) uric acid
B) creatinine
C) urea
D) amino acids
E) ketone bodies
ketone bodies
INT-7.78.
Which of the following is the most probable cause of a high uric acid
level?
A) generalized atherosclerosis
B) sarcoidosis
C) hypoparathyroidism
D) anaplastic lung carcinoma
E) aseptic necrosis of the femur
hypoparathyroidism
INT-7.85.
Which of the following statements about renal glucose secretion is
true?
A) it depends only on the glomerular filtration rate
B) the secretion occurs in the proximal tubules
C) the Tin glucose value is about 300 mg/min
D) glucose does not appear in the urine until the filtration pressure
is 50% higher than the reabsorption capacity
E) at low serum glucose values, the appearance of glucose in the
urine depends on the ratio between filtration and reabsorption
at low serum glucose values, the appearance of glucose in the
urine depends on the ratio between filtration and reabsorption
INT-7.98.
Which of the following is true if the kidney's diluting capacity is impaired,
but the concentrating ability remains intact?
A) this is due to thiazide diuretics
B) this is due to furosemide
C) this is due to mercury-containing diuretics
D) it is because the medullary part of the loop of Henle is affected
E) it is because the proximal tubule is affected
this is due to thiazide diuretics
INT-7.119.
An iso-osmotic urine usually occurs:
A) in acute tubular necrosis
B) in the hepatorenal syndrome
C) in acute glomerulonephritis
D) after a large loss of body fluids
E) after intravenous urography
in acute tubular necrosis
INT-7.120.
A marked deterioration of the concentrating ability of the kidney can
occur in:
A) hypercalcemic nephropathy
B) acute glomerulonephritis
C) chronic glomerulonephritis
D) after the constant consumption of high-protein food
E) an embolism of the renal artery
hypercalcemic nephropathy
INT-7.123.
An impaired concentrating ability with an intact diluting ability occurs
in all of the following cases, EXCEPT:
A) sickle cell anemia
B) hypokalemia
C) adrenal cortex insufficiency
D) hyperparathyroidism,
E) cystic renal disease
adrenal cortex insufficiency
INT-7.135.
The urine of healthy individuals is usually more acidic than the body
fluids due to the production and renal excretion of endogenous acids.
Which of the following is not important in the process of acid excretion?
A) the ammonia concentration
B) the free hydrogen ion concentration
C) the titratable acidity
D) all of the above
E) none of the above
the free hydrogen ion concentration
INT-7.140.
Case Study:
A 24-year-old male patient with oliguria is admitted to the hospital.
The urine sodium level is 40 mmol/L. This finding can occur in all of
the following, EXCEPT:
A) acute renal insufficiency
B) incomplete obstruction of the urinary tract
C) prerenal azotemia
D) furosemide therapy
E) therapy with ethacrynic acid
prerenal azotemia
INT-7.159.
In essential hypertension:
A) the serum sodium level is high
B) the serum sodium level is low
C) the urine sodium level is high
D) the urine sodium level is low
E) there is an increased sodium content in the vessel wall
there is an increased sodium content in the vessel wall
INT-7.172.
Which of the following mechanisms inhibits renin release?
A) a decreased pressure in the afferent arteriole
B) an elevated Na or Cl concentration in the macula densa
C) stimulation of the sympathetic renal nerves
D) hyperkalemia
E) adrenaline
hyperkalemia
INT-7.179.
Which of the following methods is commonly used for the determination
of the renin concentration?
A) determination of the angiotensin I level
B) determination of the renin with radioimmunoassay (RIA)
C) determination of the renin substrate with RIA
D) via the aldosterone secretion rate
E) determination of the angiotensin II level
determination of the angiotensin I level
INT-7.189.
Which of the following alterations does not occur in primary malignant
nephrosclerosis?
A) proliferative endarteritis of the afferent arterioles
B) proliferative endarteritis of the small interlobular arteries
C) diffuse proliferative glomerulonephritis
D) necrotizing arteriolitis
E) necrotizing glomerulitis
) diffuse proliferative glomerulonephritis
INT-7.196.
Which of the following substances can erroneously alter the
vanilly1mandelic acid values ?
A) methyldopa
B) MAO-inhibitors
C) clofibrate
D) ethanol
E) nitroglycerin
nitroglycerin
INT-7.209.
Which of the following is a sex-dependent, dominantly inherited disease?
A) Wilson's disease
B) cystinuria
C) cystinosis
D) Hartnup disease
E) vitamin D-resistant rickets
vitamin D-resistant rickets
INT-7.219.
Case Study:
A patient with lung carcinoma becomes weak and lethargic, his serum
calcium level is 16.4 mg/ 100 ml. What is the first therapeutic
intervention?
A) phosphate iv.
B) mithramycin iv.
C) glucocorticoids iv.
D) saline and furosemide iv.
E) calcitonin iv.
saline and furosemide iv.
INT-7.227.
Osteomalacia developing due to an increased excretion of phosphate
is typical of one of the following:
A) a vitamin D deficiency
B) an inherited vitamin D dependence
C) a familial vitamin D resistance
D) anti-seizure medication
E) severe liver pathology
a familial vitamin D resistance
INT-7.239.
All of the following can occur as adverse effects of cimetidine, EXCEPT:
A) increased serum transaminase levels and hepatotoxicity
B) rebound acid secretion after discontinuation of the drug
C) mental confusion
D) agranulocytosis
E) gynecomastia
rebound acid secretion after discontinuation of the drug
INT-7.268.
Which of the following pigments cannot appear in the urine?
A) hemoglobin
B) myoglobin
C) hemosiderin
D) porphyrin
E) melanin
hemosiderin
INT-7.296
Which of the following can be a sequel of bronchiectasis?
A) left ventricular dilation
B) left atrial dilation
C) a pulmonary artery embolism
D) a pulmonary vein thrombosis
E) secondary amyloidosis
secondary amyloidosis
INT-7.299.
Which of the following can be a sequel of chronic emphysema?
A) hemothorax
B) pulmonary abscess
C) secondary amyloidosis
D) left ventricular hypertrophy
E) pulmonary edema
secondary amyloidosis
INT-7.333.
The presence of anti SS-A or anti SS-B autoantibodies indicates that
polymyositis/dermatomyositis can be accompanied by one of the
following autoimmune diseases:
A) progressive systemic sclerosis (scleroderma)
B) Sjörgen's syndrome
C) Crohn's disease
D) rheumatoid arthritis
progressive systemic sclerosis (scleroderma)
INT-7.335.
Which of the following cytokines stimulates the formation of IgE?
A) IL-3
B) IL-4
C) IL-2
D) IL-1
IL-4
INT-7.340.
Which of the following cytokines does not play an important role in the
pathomechanism of rheumatoid arthritis?
A) IL-1
B) IL-3
C) TNF-alpha
D) TNF-beta
IL-3
INT-7.342.
Select the correct therapy of rheumatoid artritis (RA) complicated by
vasculitis:
A) gold salts
B) cyclophosphamide
C) chloroquine
D) sulfasalazine
cyclophosphamide
INT-7.348.
All of the following autoimmune diseases can accompany
autoimmune adrenalitis, EXCEPT:
A) immune thyroiditis
B) hypoparathyroidism
C) ovarian insufficiency
D) pernicious anemia
E) multiple sclerosis
multiple sclerosis
INT-7.366.
Medication recommended for the therapy of pneumococcus pneumonia is:
A) erythromycin
B) streptomycin
C) penicillin G
D) ampicillin
penicillin G
INT-7.369.
Which of the following statements is true for nephrogenic diabetes
insipidus?
A) an autosomal dominant inheritance
B) an autosomal recessive inheritance
C) a low GFR
D) a low serum ADH level
E) in heterozygous women, the urine concentrating capacity is
decreased
in heterozygous women, the urine concentrating capacity is
decreased
INT-7.380.
In acute poststreptococcal glomerulonephritis:
A) streptococcus pharyngitis or impetigo always develop
B) male patients are-usually affected
C) the nephrotic syndrome is the most common form of this
glomerulonephritis
D) the AST (antistreptolysin) titer correlates well with the severity
and outcome of the disease
E) all of the above
F) none of the above
none of the above
INT-7.386.
Focal segmental glomerulonephritis accompanies all of the following
diseases, EXCEPT:
A) systemic lupus erythematosus (SLE)
B) acute poststreptococcal glomerulonephritis
C) polyarteritis nodosa
D) Henoch-Sch6nlein purpura
E) bacterial endocarditis
acute poststreptococcal glomerulonephritis
INT-7.381.
Acute nephritis occurs in all of the following, EXCEPT:
A) essential mixed cryoglobulinemia
B) Guillain-Barré's syndrome
C) acute porphyria
D) solid tumors after irradiation
E) Coxsackievirus infection
acute porphyria
INT-7.383.
The light microscopic histologic picture, similar to that of
mesangiocapillary glomerulonephritis, is observed in all of the following
diseases, EXCEPT:
A) systemic lupus erythematosus (SLE)
B) scleroderma
C) Henoch-Sch6nlein purpura
D) poststreptococcal glomerulonephritis
E) sickle cell anemia
scleroderma
INT-7.238. Single Choice Question
The most pronounced gastrointestinal fluid absorption occurs in
the:
A) duodenum
B) jejunum
C) ileum
D) colon
E) none of the above
jejunum
INT-7.141.
Case Study:
A 25-year-old female patient is admitted with metabolic alkalosis. The
chloride concentration in the urine exceeds 110 mmol/L. This fording
can occur in all of the following, EXCEPT:
A) severe vomiting
B) diuretic therapy
C) severe potassium loss
D) Bartter's syndrome
E) Cushing's syndrome
severe vomiting
INT-7.373.
Nephrosis occurs in all of the following, EXCEPT:
A) right heart insufficiency
B) constrictive pericarditis
C) obstruction of the inferior caval vein above the renal artery
D) polycystic kidney disease
E) amyloidosis
polycystic kidney disease
INT-7.560. MC
The intensity of cardiac murmurs:
A) increases on the right side during expiration
B) amyl nitrate increases the murmur in aortic stenosis
C) increases during Valsalva's maNEUver in hypertrophic obstructive
cardiomyopathy
D) in mitral stenosis the intensity of the murmur depends on the
extent of the stenosis
E) increases during a physical load in aortic insufficiency
BCE
NT-7.714. MC
Which of the following features are characteristic of Bence-Jones
protein?
A) it is found in the urine of 70% of patients with myeloma
B) it precipitates at 37
0
C and is redissolved at higher temperatures
C) it is comprised of both kappa and lambda chains
D) the "Albustix" test is positive
E) when it is present the risk of renal symptoms is increased
AE