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26 Cards in this Set

  • Front
  • Back
Secretes glucagon
alpha cells
Secretes insulin
beta cells
Secretes somatostatin
delta cells
glucose from aa's
gluconeogenesis
glucose into glycogen
glycogenesis
glycogen into glucose
glycogenolysis
Primary control of insulin
blood glucose level
Target tissues of insulin
adipose
muscle
liver
Insulin independent tissues
CNS
Retina
Kidney
RBC
What does insulin do in muscle cells
increased glucose entry, glycogen synthesis, AA and K+ uptake

Decreased protein breakdown
Insulin's affect on the liver
inhibits gluconeogenesis
increases glycogen stores, glycogen buffer
Enzyme that stores glucose as glycogen in the liver
glucokinase
What does a lack of glucose do to adipose tissue
increases fatty acid synthesis
activates lipoprotein lipase
increases K+ uptake
increases LDL and cholesterol
Deficiency of ADH
Diabetes insipidus
Excessive fluid loss d/t overproduction of gluccocorticoids
adrenal diabetes
Insulin dependent area of the brain that is responsible for hunger
hypothalamus
What are some of the metabolic changes that occur due to DM
increased fat and protein metabolism
decreased Na and K
Hyperglycemia
Dehydration
Stimulates B cells to release more insulin
sulfonylureas
Suppress liver output of glucose
metformin
Make cells more receptive to insulin
Rezulin
Normal fasting glucose level
90-100
How long does it normally take glucose levels to get back to normal after glucose tolerant test
2 hours
What is the action of glucagon on carbs
increase hepatic glucose production and release
promotes glycogenolysis
decrease glycogen synthesis
What is the action of glucagon on fats
enhances ketone production
ketogenesis- break down of fats to ketone bodies
Inhibits triglyceride synthesis
What is the action somatostatin
inhibits GH
decreases GI motility
What are the components of metabolic syndrome
obesity
hyperglycemia
insulin resistance
lipid abnormalities
HTN