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44 Cards in this Set

  • Front
  • Back
Name 5 most common forms of soft tissue Rheumatism
Bursitis, tendinitis
Adhesive capsulitis
Reflex sympathetic dystrophy
Dupuytren's contracture
Fibromyalgia syndrome
Whats the etiology of bursitis and tendinitis?
Trauma
inflammation: RA, SLE, gout
infection: staph and strep
Common sites of bursitis and tendinitis?
subacromial
olecranon
illiopsoas
trochanteric
ischiogluteal
prepatellar
anserine
retrocalcaneal
what are the signs and symptoms of bursitis?
Acute: pain, tenderness (in case of subdeltoid bursitis on lateral side of the upper arm
Chronic: chronic annoying pain
Chronic cases of bursitis might cause?
Adhesive capsulitis
Whats happening in tennis elbow?
Lateral epicondylitis
inflammation of the origin of the common extensor tendon
pain at the lateral elbow, radiation above and down
point tenderness at the lateral epicondyle
pain worse by resisted extension of the wrists
Whats happening in Olecranon bursitis?
Caused by trauma, inflammation (RA and gout)
swelling, little spontaneous pain
pain on palpation if not infected
Sepsis of the olecranon bursa?
pain and swelling
erythema, heat and tenderness
gram stain and culture with aspiration of fluid
What is DeQuervain's disease?
tendinitis of the radial tendons
wrist pain on the radial side
tenderness on palpation
caused by trauma, direct of repetitive
Whats bursitis?
inflammation of bursa overlaying the bone
pain... usually radiated
tenderness
caused usually by trauma
Why can iliopsoas bursitis be confused by arthritis?

what is the complication of iliopsoas bursitis?
both cause pain in the groin area
iliopsoas bursitis is inflammation of bursa anterior to the hip joint, behind the iliopsoas muscle
a cystic mass may compress the femoral vein and causes venous distention in the knee and the leg
pain is worse on extension of hip
diagnosis by CT or MRI
Whats anserine bursitis?
inflammation of the sartorius bursa (between common tendon of sartorius, racillis and semitendinosus, medial aspect of the knee)
pain and tenderness on palpation
what does erythema, heat and tenderness suggest in prepatellar bursitis?
prepatellar bursitis is swelling over the patella
heat and erythema suggests infection
Whats a must do when there is a chance of infection in bursitis or tendinitis?
Fluid aspiration and culture
What is cause of adhesive capsulitis of the shoulder (frozen shoulder)?
usually shoulder bursitis or tendinitis
trauma
immobility
coronary artery disease (CAD)
Whats the pathology and clinical findings in adhesive capsulitis of the shoulder?
decreased range of motion
diffuse pain
thickening of the joint capsule
proliferation of synovial lining membrane and small blood vessels
mild chronic inflammation
calcification (late stages)
How do you differentiate adhesive capsulitis with RA?
in RA you will see juxtarticular osteopenia and bone erosion on the x-ray
Reflex sympathetic dystrophy
or
Complex regional pain syndrome

what is the clinical manifestation
chronic pain in the extremity
decreased range of motion due to associated adhesive capsulitis
initially: swelling, warmth and erythema in extremity
later: cold, raynaud's phenomenon, loss of hair, extreme tenderness
Whats the histology of Complex regional pain syndrome?
same as capsulitis.

thickening of the joint capsule
proliferation of synovial lining membrane and small blood vessels
mild chronic inflammation
calcification (late stages)
Whats the cause of Complex regional pain syndrome?
prolonged immobilization due to:
trauma
bicipital tendinitis
hemiplegia
Whats the mechanism of Complex regional pain syndrome?
increased sympathetic activity resulting form trauma
with internuncial neuronal excitation in the spinal column
with activation of adjacent symptomatic effector neurons
allodynia?
stimulus that causes pain
probably touch or pressure

characteristic of fibromyalgia
What is Duputren's Contracture?
nodular thickening and shortening of the palmar fascia
unilaterally or bilaterally
puckering and dimpling of the skin
gradual flexion contracture mostly in 4th and 5th fingers
proliferation and then contraction of the myofibroblasts
most seen in men!
whats the treatment for Duputren's contracture?
Steroid injection
local injection of collagenase clostridium histolyticum (Xiaflex)
limited fasciectomy
What percent of population and who get Fibromyalgia?
3-3.5%
80-90% female
peak age 40-60
people with concurrent medical
Whats the importance of FMS?
immense suffering and poor quality of life
high cost to the society
much morbidity
increased risk of cancer and mortality
What is FMS?
A chronic, widespread musculoskeletal pain syndrome
tender points on palpation at multiple sites
Name the most important symptoms of FMS
Widespread pain
fatigue
stiffness
cognitive difficulties
Tissue swollen feeling
dizziness
What are some disease associations with FMS?
Irritable bowel syndrome
headache - tension type
migraine headaches
chronic fatigue syndrome
restless legs syndrome
temporomandibular joint
What are tender points?
tenderness on palpation of local tissues such as muscles, ligaments or joint
elicited by applying force (4kg)
What are physical findings in FMS?
tender points
no swelling (feels swollen)
no neurological findings
signs of accompanying disease (arthritis or neuritis)
ACR classification of FMS?
Widespread aching
>11 tender points among possible 18 sites
What is the pathophysiology of FMS?
disease of the central nervous system with central sensitization
no structural pathology in peripheral tissues
peripheral nociception generators (trauma, arthritis) may trigger central sensitization
whats the neuroplasticity seen in FMS?
greater sensitivity to peripheral stimuli, pressure, heat
spread of pain beyond area of stimulus
prolonged pain after stimulus
What is central sensitization?
wind up!
Nociceptive output> nociceptive input
repetitive nerve discharge --> sensory amplification
increased pain transmission and decreased modulation
What causes central sensitization?
Genetic factors
non-restorative sleep
physical trauma
viral infection
inflammation (RA or OA may trigger central sensitization)
Psychological distress
What is seen in SPECT Scan of brain in FMS?
decreased blood flow in caudate nuclei and thalami
What are the psychological factors that affect FMS?
psychological distress 35%
depression
metal stress
poor coping
catastrophizing
What syndromes are in part of central sensitivity syndromes?
FMS, PTSD, Chronic fatigue syndrome, irritable bowel syndrome, headaches, temporomandibular dysfunction, restless leg syndrome, interstitial cystitis, multiple chemical sensitivity
How do you manage FMS?
empathy and education
exercise
sleep hygiene
behavioral therapy for coping
serotonergic and epinephric drugs
pregabalin
What is pregabalin (Lyrica)?
binds to the alpha-delta subunit of voltage gated Ca channel
decrease Ca influx to cell
reduce the release of substance P and glutamate
What is Duloxetine (Cymbalta)?
selective serotonin and norepinephrine reuptake inhibitor (SNRI)
What is Milnacipran (Savella)?
SNRI
What drugs are used in treatment of FMS?
serotonergic and epinephric drugs:
amitriptylene, cymbalta, tramadol, milnacipran
Pregabalin