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14 Cards in this Set
- Front
- Back
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Cyclosporine
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Binds cyclophilin stopping T-Cell from responding to antigens
Can rescue GvH disease Nephrotoxic HTN Hyperglycemia |
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Tacrolimus
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Binds FK protein stopping T-Cell activation
Can rescue GvH disease |
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Sirolimus
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Binds FK protein and mTOR blocking T and B cell activation and proliferation
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Mycophenolate mofetil
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Inhibit IMPDH inhibiting lymphocyte proliferation and function
Good for transplants |
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Thalidomide
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Immunosuppressant
Teratogen |
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Azathioprine
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Block purine synth, inhibit B/T cell prolif
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Cyclophosphamide
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Alkylating agent
Used for autoimmune disease Hemorrhagic cystitis Hematuria |
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Rh Ig
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Used to block Rh(+) antigen from being recognized by Rh(-) mother
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Rituximab
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Ab against CD20
Kills all B cells, not plasma cells |
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Eculizamab
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Binds terminal C5 blocking inflammation
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Trastuzumab
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Ab binds HER2/neu arresting cell division
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Aldesleukin
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IL-2 analogue
Used to improve T cell count (HIV) |
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Leflunomide
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Blocks dihydroorotate dehydrogenase stopping UMP formation bad for lymphocytes mostly
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Anti-thymocyte globulin
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Ab against T-Cells
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