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34 Cards in this Set

  • Front
  • Back
Dorsal Column
cell of origin
ipsilateral dorsal root ganglia that alpha-betas; 6 microns
fasciculus gracilis=T7 and below-leg

fasciculus cuneatus=T6 and above (arm
Dorsal column
location
pathway
dorsal funiculus
pathway: within the dorsal funiculus and in within the medulla the fibers cross over
Dorsal column
termination
ipsilateral nucleus gracilis and nucleus cuneatus
Dorsal column lesion deficit
ipsi 2 pt. discrimination, vibration, conscious proprioception, asterognosia, agraphesthesia, ataxia
Anterolateral system
cells of origin
contralateral dorsal horn
DRG cell types: delta fiber, c fiber
Anterolateral system
location and pathway
location:anterolateral quadrant of lateral funiculus
pathway: dorsal root fibers enter at zone of lissauer and ascend two levels to synapse onto dorsal horn neurons that cross to reach the anterolateral system
Anterolateral system
lesion deficits
contralateral loss of pain, temp and crude touch
Anterolateral system
termination
ipsilateral ventral posterolateral nucleus (VPL) of thalamus

VPL-->somatosensory cortex (areas 3, 1 and 2)
Anterolateral system
what happens C2 and C1 since dorsal root fibers need to ascend two levels normally?
C2 fibers terminate in spinal nucleus V (part of trigeminal)

C1 has no dorsal root
Dorsal Spinocerebellar tract (DCST)
cells of origin (1)
medial 1a, II, (muscle spindles) 1b (golgi tendon organs) fibers of dorsal root
Dorsal spinocerebellar tract
location of intraspinal cells (2)
1a, II, 1b fibers terminate on Clarke's Column (C8-L3 at lamina VII/base of dorsal horn)

fibers reach cerebellum via the dorsolateral part of lateral funiculus
Dorsal spinocerebellar tract
termination (3)
ipsilateral cerebellum via inferior cerebellar peduncle
Dorsal spinocerebellar tract
Lesions
ipsilateral muscle incoordination/ataxia
dorsal spinocerebellar tract
How do 1a, II, 1b fibers deal with the fact that clarke's column is only C8-L3
from below L3-->use fasciculus gracilis until L3 to reach Clarke's

From above C8: enter the cord and ascend within fasciculus cuneatus until they reach the caudal medulla's accessory cuneate nucleus. these cells then project to the ipsi cerebellum like C8-L3 do.
Dorsal spinocerebellar tract overview
Basically uses two tracts:
C2-C7-fasiculus cuneatus-->accessory cuneatus nucleus in the medulla

C8-L3-uses the dorsal spinocerebellar tract
Lateral corticospinal tract (LCST)
cells of origin (1)
Corticospinal tract: area 4/precentral gyrus of motor cortex send very long axons that cross at C1 (pyramidal decussation)
Lateral Corticospinal tract fibers (LCST): crossed corticospinal fibers enter lateral funiculus
Lateral corticospinal tract
location and course of axons
1) pyramid of medulla
2) axons cross at caudal medulla in pyramdial decussation
3) axons enter the lateral funiculus of spinal cord where they comprise lateral corticospinal tract
Lateral corticospinal tract
termination
ipsilateral (relative to fibers at C1) ventral horn motor neurons
Lateral corticospinal tract
Lesion deficits general
rostral to pyramidal decussation-contralateral
caudal to pyramidal decussation-ipsilateral
Lateral corticospinal tract
Lesion deficits clincally
1) ipsilateral muscle weakness-->Hemiplegia
2) spasticity (seen when passively moving muscle)
3)clonus: hyperreflexia
4) Babinski sign
Lateral corticospinal tract
reflexes effected
1) cutaneomuscular abdominal and cremasteric reflexes
2) Babinkski sign present
3) Chaddock sign
4) Bing Sign
5) Hoffman sign
6) loss of cremasteric reflex
ventral horn cells
lower motor neurons
axial muscles
motor neurons are medial to those controlling distal muscles
flexors versus extensors
flexors lie dorsal to those controlling extensors
T1 and below
LMNs are associated with axial musculature
Lesions in LMNs
atrophy, flaccidity, atonicity and areflexia
LCST and LMN relationship
Upper motor neuron pathway (LCST) synapses onto LMNs
Lesion in UMN
spasticisity, but no atrophy
Spinal shock
acute: atonia and flacidity below levels of lesion, chronic: weakness and spasticity
Lateral Horn: cells of origin
1) preganglionic sympathetic cells from T1-L2, 2) hypothalamus
Lateral Horn: location
lateral cell column axons pass through white communicating rami
Lateral Horn: options of preganglionic fibers
1) synapse within paravertebral ganglia, 2) ascend or descend, 3) exit to become splanchnics
Lateral Horn: termination
T1 to T5 ascend to superior cervical ganglion
Lateral horn: lesions
1) Horners- T1 lesion, 2) T1-L2-loss of sweating in area of deinnervation, 3) C1 to T1-loss of sweating over entire body ipsilateral to lesion