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30 Cards in this Set

  • Front
  • Back
Specialized PFT's
Maximal Voluntary Vent. (MVV)

Single-Breath Carbon Monoxide

Mathacholine Challenge Testing

Closing Volume

Exercise Testing
Indication for MVV
MVV reflects overall status of lung-thorax to provide peak ventilation available to meet physiologic demands
Technique for MVV
Pt breathes rapidly and deeply as possible for 12-15 secs

Total volume exhaled is recorded

Multiplied x 5 or 4 for a total volume moved by lungs in 1 min
Predicted Normal MVV for young healthy adults
170 L/M
How can validity of MVV be est?
Multiplying FEV1 x 35
Why isn't MVV a very useful test?
Results vary widely

Very effort dependent
Indication for Carbon Monoxide Diffusing Capacity
To elvaluate the ability of a gas to dffuse across the A-C membrane of the lungs
-Idiopathic Pulm. Fbrosis
-Emphysema
-Primary Pulm. Hypertension
-Evaluation of Lungs 2ndary to systemic disease
Factors affecting diffusing capacity
Diffusion coefficient of the gas used in testing

Surface area of the A-C membrane

Thickness of the A-C membrane

Blood vol and flow n the Pulm. Cap. network

Distribution of the insp gas

Hematocrit
Sngle Breath Carbon Monoxide Diffusing Capacity Tech.
CO has greater affinity to bind to Hb (210x)

Pt maximally inspires gas mixture

10 sec breath hold

Pt exhales and concentrations of He and CO are analyzed
-He reflects dilution
-Initial PCCO calculated before dffusion
Gas Mixture for DLCOsb
.3-,4% CO

10% He

Air
Nomal Resting DLCOsb for an avg young man
25 mL/min/mm Hg CO

women's is slightly lower (smaller lungs)
DLCO increases with
Exercise (2-3X)
DLCO decreases with
Restrictive Lung disease (pulm fibrosis)
Methacholine Challenge Testing AKA
Bronchial Provocation Testing
MCT Description
Assessing airway responsiveness in which the pt inhales an aerosol of one or more concentrations of methacholine to induce bronchospasm

Spirometry s performed pre and post to quantitate response
MCT Positive result
A decrease in FEV1 value of 20% from baseline
MCT that causes a decrease from baseline is called...
Provocative Concentration

or

Provacative Dose
Indications for MCT
Diagnosis of airway hyperactvity (asthma)

Occupational Asthma

Severity of Hyperresponsiveness

The risk of developing asthma

Response to therapeutic interventions
-increase in FEV1 by 12% or greater
-increase in FVC 200 mL or greater
Testing Conditions for MCT
Pt must be asymptomatic at baseline

Bronchodialators and anti-histamines must be withheld from the pt before test

Inhaled corticosteroids should not be withheld

Emergency equipment should be readily available
MCT Technique
Baseline FEV1 are measured

First dose adminitered is 0.025 mg/mL

Dosing schedules are used each time doubling dose up to a max of 25 mg/mL

Test s concluded once a PD20% is reached (document dosage)
MCT Results in the healthy
-Do NOT show a decrease of 20% in FEV1 during testing
-PD20% is greater than the max dosage used in testing
MCT Results in pt with Hyperreactve airways
Positive Test

PD20% is achieved with 8 mg/mL or less
Closing Vol
A special form of nitrogen washout used for early diagnosis of obstruction in the small airways (COPD)
Closing Vol Technique
Pt inhales a single breath - 100% FIO

Slowly exhales completely while N2 concentrations are monitored and plotted against exhaled vol.

Four phases are clearly seen
Four Phases of Closing Vol
I: Anatomic dead space contain mostly 100% O2

II: Mixture of deadspace & alv gas

III: Alv Plateau (Alv gas)

IV; Airway closure in bases and emptying of apices
Normal results for CV in healthy results
10% of VC
CV in a 60 Year Old
40%
Increase in CV is in indicator of ...
Small airway obstruction
Indications for Exercise Testing
To determine whether exercise limitations is caused by Pulm. or Cardio insufficiency

To evaluate work capacity and to provide direction

To demonstrate oxygen desaturation and determine supplemental O2 therapy via 6 mn walk test
Types of Exercise Testng
Stress Electrocardiography

Vent. Capaciity

Blood Gas Defects

Exercise Challenge

Anaerobic Threshold

Max. Oxygen Uptake

6 Min Walk Test (6MWT)