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24 Cards in this Set

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Hypotonic Hyponatremia: Evaluation
with a Urine osmolarity < 100 mOsm/L
n Psychogenic polydipsia
n Beer drinker’s potomania
n Tea and toast
Renal Solute Excretion/Minimum Urine Osmolarity =
Maximum Renal Water Excretion
*Daily solute load
10 mOsm/Kg weight
Hypovolemic Hyponatremia with a Urine Na > 20 mEq/L is caused by
n Diuretics
n Mineralcorticoid deficiency
n Salt wasting nephropathy
n Osmotic diuresis
Euvolemic Hyponatremia with
Urine Osm < 100 is caused by
n Tea and toast
n Beer Potomania
n Psychogenic polydipsia
Euvolemic Hyponatremia with a Urine Osm > 100 causes include
n SIADH
n Postoperative
n Hypothyroidism
n Cortisol deficiency
n Endurance exercise
n Medications
n SIADH
n Postoperative
n Hypothyroidism
n Cortisol deficiency
n Endurance exercise
n Medications
Euvolemic Hyponatremia with a Urine Osm > 100 causes include
Drugs Associated with euvolemic Hyponatremia
n Desmopressin (DDAVP)
n Carbamazepine
n Antipsychotics/A Antidepressants
n Selective serotonin reuptake inhibitor

n Methylamphetamine
n Desmopressin (DDAVP)
n Carbamazepine
n Antipsychotics/A Antidepressants
n Selective serotonin reuptake inhibitor

n Methylamphetamine
Drugs Associated with euvolemic Hyponatremia
n Clinical euvolemia
n Urinary Na > 20 mEq/L
n Absence of adrenal, thyroid or renal
disease
Diagnostic Criteria for SIADH
Hypervolemic Hyponatremia caused by
n Edematous states
n Cirrhosis
n Congestive heart failure
n Nephrotic syndrome
n Advanced kidney disease
Hypotonic Hyponatremia: Treatment for asymptomatic hypovolemics
normal saline)
Hypotonic Hyponatremia: Treatment for Hypervolemics
Hypervolemic (loop diuretics + water
restriction)
Hypotonic Hyponatremia: Treatment of euvolemics
Water restrict
the primary defense
against hypernatremia
thiirst
Renal concentrating mechanisms requires what
the creation of a hypertonic medullary interstitium, osmotic equilibration of urine within the collecting duct with the interstitium and the prescence of ADH
Urine osmolarity of hypernatremia is appropriate if
n Appropriate if > 400 - 800
decreased total body water as well as total body sodium causes what?
Hypovolemic hypernatremia
decreased total body water as well as total body sodium causes Hypovolemic hypernatremia and if the sodium in the urine is found to be greater than 20 then the hypernatremia is probably due to
a renal cause like osmotic or loop diuretics or postobstruction
decreased total body water as well as total body sodium causes Hypovolemic hypernatremia and if the sodium in the urine is found to be less than 20 then the cause is due to
extrarenal causes such as excess sweating, burns and diarrhea
a decrease in total body water with no change in sodium results in
Euvolemic Hypernatremia
a decrease in total body water with no change in sodium results in results in euvolemic hyponatremia and renal causes are
Renal losses
n Diabetes insipidus
n Hypodipsia (hypothalamic disorders)
a decrease in total body water with no change in sodium results in results in euvolemic hyponatremia and extrarenal causes are
Extrarenal losses
n Insensible losses, respiratory
Sodium gains
n Primary hyperaldosteronism
n Hypertonic sodium bicarbonate

cause
an increase in TBW and Sodium resulting in hypervolemic hypernatremia