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13 Cards in this Set

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  • Back
SLE
-multi-system AT disease of unknown etiology
-a "connective tissue" dz
typical lupus pt
1. female
2. 15-45
3. F>M
4. can occur at any age
5. blacks and hispanics 2-4x more frequent
SLE classification criteria
1. malar rash- rash across bridge of nose, raised or flat, do not effect nasolabial fold
2. discoid rash-raised patches
3. photosensitivity
4. oral ulcers
5. arthritis
6. serositis
7. renal disorder
8. neuro disorder
9. hematologic disorder
10. immunologic disorder
11. ANA
lab hallmark of SLE
-ANA
->98% of pts with SLE have elevated serum levels of ANA
-test is not specific for SLE
-if ANA is +:
1. dsDNA
2. anti-SM
3. anti-histone
4. folow pts with LUPUS complement C3 and C4
Labs
1. CBC
2. ESR
3. U/A
4. RF
5. ANA
6. CPK
7. Chemscreen
8. thyroid functions
most common courses of death in lupus pts
1. infx
2. lupus nephritis and renal failure
3. CV dz
4. CNA lupus
-sever lupus is uncommon!
Anti phospholipid syndrome (APLS)
-venous thrombosis
-arterial thrombosis
-recurrent feta loss
-thrombocytopenia
organ involvement in SLE
1. joints- 90%
2. skin
3. serositis
4. kidney
5. raynauds
6. mucosa
7. CNA
raynauds phenomenon
-must be 2 or 3 fold
-blue, red, white
CNS
1. seizures
2. hemiparesis
3. CN lesions
4. stem/cord lesions
5. aseptic meningitis
6 transverse myelitis
PNS
1. peripheral neuropathies
2. myasthenia gravis
3. mononeuritis multiplex- vasculitis assoc with lupus, causes and infarct
Psychiatric
1. organic and non organic
treatment
1. NSAIDs
2. PLaquentil
3. Methotrexate
4. Steroids
5. Assess osteoporosis
6. sunscreens
7. immunizations