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89 Cards in this Set

  • Front
  • Back
malignant fat tumor
large
will recur unless excised
liposarcoma
most common soft tissue tumor of childhood
malignant
rhabdomyosarcoma
rhabdomyosarcoma
most common soft tissue in kids
malignant
skel muscle
usually head/neck
flat discoloration < 1 cm
macule
macule > 1 cm
patch
elevated skin lesion < 1 cm
papule
papule > 1 cm
plaque
small fluid containing blister
vesicle
transient vesicle
wheal
large fluid containing blister
bulla
irregular, raised lesion resulting from scar tissue hypertrophy (follows trauma to skin, usually in African Americans)
keloid
blister with pus
pustule
dried exudates from a vesicle, bulla, or pustule
crust
hyperkeratosis with retention of nuclei in stratum corneum
parakeratosis (example: psoriasis)
increased thickness of stratum corneum
hyperkeratosis (example: psorioasis)
separation of epidermal cells
acantholysis
epidermal hyperplasia
acanthosis
inflammation of the skin
dermatitis
example of macule
tinea versicolor
example of papule
acne vulgaris
example of plaque
psoriasis
example of vesicle
chickenpox
example of wheal
hives
example of bulla
bullous pemphigoid
example of pustule
impetigo
example of hyperkeratosis and parakeratosis
psoriasis
example of acantholysis
pemphigus vulgaris
verrucae
warts
soft tan cauliflower like lesions
soft tan cauliflower like lesions
verrucae (warts)
warts on hands
verruca vulgaris
genital warts
condyloma accuminatum (HPV)
nevocellular nevus
common mole
urticaria
hives
intensely pruritic wheal that forms after mast cell degranulation
ephelis
freckle
normal number of melanocytes, increased melanin pigment
atopic dermatitis (eczema)
pruritic eruption
common on skin flexures
associated with asthma, allergies
pruritic eruption
common on skin flexures
associated with asthma, allergies
atopic dermatitis (eczema)
freckle
ephelis
hives
urticaria
psoriasis
papules and plaques
silvery scaling
usually knees and elbows
inc stratum spinosum
dec stratum granulosum
inc stratum spinosum
dec stratum granulosum
psoriasis
papules and plaques
silvery scaling
usually knees and elbows
psoriasis
auspitz sign
psoriasis
bleeding spots when scales are scraped off
psoriasis association
nail pitting
psoriatic arthritis
seborrheic keratosis
flat, greasy, pigmented squamous epithelial proliferation with keratin filled cysts (horn cysts)

head, trunk, extremities
benign, older
flat, greasy, pigmented squamous epithelial proliferation with keratin filled cysts (horn cysts)
seborrheic keratosis
albinism: normal melanocyte number with dec melanin production due to dec activity of what enzyme?
tyrosinase
albinism cause
failure of neural crest cell migration
vitiligo
irregular areas of complete depigmentation,
due to dec in melanocytes
melasma
hyperpigmentation associated with pregnancy (mask pregnancy) or OCP use
impetigo
very superficial skin infection
S aureus or S pyogenes
very contagious
honey colored crusting
honey colored crusting, superficial skin infection
impetigo
cellulitis
acute, painful spreading infection
dermis or subcutaneous tissue
s aureus or s pyogenes
necrotizing fasciitis
deeper tissue injury
from anaerobic bacteria and s pyogenes
(flesh eating bacteria)
necrotizing fasciitis results in crepitis due to
methane and CO2 production by bacteria
staph scalded skin syndrome cause
exotoxin
destroyes keratinocyte attachments to stratum granulosum only
staph scalded skin syndrome symptoms
fever
general erythematous rash with slouging of upper layers of epidermis
newborns and kids
fever
general erythematous rash with slouging of upper layers of epidermis
newborns and kids
staph scalded skin syndrome
hairy leukoplakia
white, painless plaques on tongue that cannot be scraped off.
EBV
sort of specific for HIV
pemphigus vulgaris
potentially fatal autoimmune disorder
IgG ab against desmosomes
(anti epithelial cell ab)
shows immunofluourescence throughout epidermis
pemphigus vulgaris
acantholysis- intraepidermal bullae of skin and oral mucosa
pemphigus vulgaris
positive Nikolskys sign (separation of epidermis when stroking the skin)
pemphigus vulgaris
bullous pemphigoid
autoimmune
IgG ab against hemidesmosomes (epidermal basement membrane)
linear immunofluorescence
eosinophils in blisters
affects skin but not oral mucosa
negative nikolskys sign
bullous pemphigoid
dermatitis herpetiformis
pruritic papules and vesicles
deposits of IgA at tips of dermal papillae
celiac disease
celiac disease skin disorder
dermatitis herpetiformis
erythema multiforme
associated with infections, cancers, drugs, autoimmune

multiple lesions- macules, papules, vesicles, target lesions
stevens johnson syndrome
fever
bullae
necrosis
sloughing of skin
high mortality
due to drug reaction
fever
bullae
necrosis
sloughing of skin
high mortality
due to drug reaction
stevens johnsons syndrome
toxic epidermal necrolysis
more severe than stevens johnson with greater epidermal involvement
lichen planus
pruritic
purple
polygonal papules
sawtooth infiltrate of lymphocytes at dermal-epidermal junction
hep C assoc
pruritic
purple
polygonal papules
sawtooth infiltrate of lymphocytes at dermal-epidermal junction
hep C assoc
lichen planus
actinic keratosis
premalignant lesions due to sun exposure
small, rough, erythematous, or brown
cutaneous horn
actinic keratosis can predispose to
squamous cell carcinoma
cutaneous horn
actinic keratosis
acanthosis nigricans
hyperplasia of stratum spinosum
assoc with hyperlipidemia and visceral malignancy
erythema nodosum
inflammatory lesions of subcutaneous fat,
usually on anterior shins,
associated with:
coccido, histo, TB, leprosy, strep, sarcoid
inflammatory lesions of subcutaneous fat,
usually on anterior shins,
associated with:
coccido, histo, TB, leprosy, strep, sarcoid
erythema nodosum
pityriasis rosea
"herald patch" followed days later by "christmas tree" distribution

multiple papular eruptions,
resolves spontaneously
palisading nuclei
bcc
exposure to sun and arsenic
scc
scc locations
hands and face
ulcerative red lesion
keratin pearls
scc
associated with chronic draining sinuses
scc
rolled edges with central ulceration
pearly papules
bcc
s-100 tumor marker
melanoma
melanoma: risk of mets correlates with
depth of tumor
dark with irregular borders
melanoma
precursor to melanoma
dysplastic nevus (atypical mole)