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89 Cards in this Set
- Front
- Back
malignant fat tumor
large will recur unless excised |
liposarcoma
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most common soft tissue tumor of childhood
malignant |
rhabdomyosarcoma
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rhabdomyosarcoma
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most common soft tissue in kids
malignant skel muscle usually head/neck |
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flat discoloration < 1 cm
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macule
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macule > 1 cm
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patch
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elevated skin lesion < 1 cm
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papule
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papule > 1 cm
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plaque
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small fluid containing blister
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vesicle
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transient vesicle
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wheal
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large fluid containing blister
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bulla
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irregular, raised lesion resulting from scar tissue hypertrophy (follows trauma to skin, usually in African Americans)
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keloid
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blister with pus
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pustule
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dried exudates from a vesicle, bulla, or pustule
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crust
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hyperkeratosis with retention of nuclei in stratum corneum
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parakeratosis (example: psoriasis)
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increased thickness of stratum corneum
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hyperkeratosis (example: psorioasis)
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separation of epidermal cells
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acantholysis
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epidermal hyperplasia
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acanthosis
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inflammation of the skin
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dermatitis
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example of macule
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tinea versicolor
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example of papule
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acne vulgaris
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example of plaque
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psoriasis
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example of vesicle
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chickenpox
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example of wheal
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hives
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example of bulla
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bullous pemphigoid
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example of pustule
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impetigo
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example of hyperkeratosis and parakeratosis
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psoriasis
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example of acantholysis
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pemphigus vulgaris
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verrucae
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warts
soft tan cauliflower like lesions |
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soft tan cauliflower like lesions
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verrucae (warts)
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warts on hands
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verruca vulgaris
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genital warts
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condyloma accuminatum (HPV)
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nevocellular nevus
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common mole
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urticaria
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hives
intensely pruritic wheal that forms after mast cell degranulation |
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ephelis
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freckle
normal number of melanocytes, increased melanin pigment |
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atopic dermatitis (eczema)
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pruritic eruption
common on skin flexures associated with asthma, allergies |
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pruritic eruption
common on skin flexures associated with asthma, allergies |
atopic dermatitis (eczema)
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freckle
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ephelis
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hives
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urticaria
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psoriasis
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papules and plaques
silvery scaling usually knees and elbows inc stratum spinosum dec stratum granulosum |
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inc stratum spinosum
dec stratum granulosum |
psoriasis
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papules and plaques
silvery scaling usually knees and elbows |
psoriasis
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auspitz sign
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psoriasis
bleeding spots when scales are scraped off |
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psoriasis association
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nail pitting
psoriatic arthritis |
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seborrheic keratosis
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flat, greasy, pigmented squamous epithelial proliferation with keratin filled cysts (horn cysts)
head, trunk, extremities benign, older |
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flat, greasy, pigmented squamous epithelial proliferation with keratin filled cysts (horn cysts)
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seborrheic keratosis
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albinism: normal melanocyte number with dec melanin production due to dec activity of what enzyme?
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tyrosinase
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albinism cause
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failure of neural crest cell migration
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vitiligo
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irregular areas of complete depigmentation,
due to dec in melanocytes |
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melasma
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hyperpigmentation associated with pregnancy (mask pregnancy) or OCP use
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impetigo
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very superficial skin infection
S aureus or S pyogenes very contagious honey colored crusting |
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honey colored crusting, superficial skin infection
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impetigo
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cellulitis
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acute, painful spreading infection
dermis or subcutaneous tissue s aureus or s pyogenes |
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necrotizing fasciitis
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deeper tissue injury
from anaerobic bacteria and s pyogenes (flesh eating bacteria) |
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necrotizing fasciitis results in crepitis due to
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methane and CO2 production by bacteria
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staph scalded skin syndrome cause
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exotoxin
destroyes keratinocyte attachments to stratum granulosum only |
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staph scalded skin syndrome symptoms
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fever
general erythematous rash with slouging of upper layers of epidermis newborns and kids |
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fever
general erythematous rash with slouging of upper layers of epidermis newborns and kids |
staph scalded skin syndrome
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hairy leukoplakia
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white, painless plaques on tongue that cannot be scraped off.
EBV sort of specific for HIV |
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pemphigus vulgaris
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potentially fatal autoimmune disorder
IgG ab against desmosomes (anti epithelial cell ab) |
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shows immunofluourescence throughout epidermis
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pemphigus vulgaris
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acantholysis- intraepidermal bullae of skin and oral mucosa
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pemphigus vulgaris
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positive Nikolskys sign (separation of epidermis when stroking the skin)
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pemphigus vulgaris
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bullous pemphigoid
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autoimmune
IgG ab against hemidesmosomes (epidermal basement membrane) |
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linear immunofluorescence
eosinophils in blisters affects skin but not oral mucosa negative nikolskys sign |
bullous pemphigoid
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dermatitis herpetiformis
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pruritic papules and vesicles
deposits of IgA at tips of dermal papillae celiac disease |
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celiac disease skin disorder
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dermatitis herpetiformis
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erythema multiforme
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associated with infections, cancers, drugs, autoimmune
multiple lesions- macules, papules, vesicles, target lesions |
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stevens johnson syndrome
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fever
bullae necrosis sloughing of skin high mortality due to drug reaction |
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fever
bullae necrosis sloughing of skin high mortality due to drug reaction |
stevens johnsons syndrome
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toxic epidermal necrolysis
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more severe than stevens johnson with greater epidermal involvement
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lichen planus
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pruritic
purple polygonal papules sawtooth infiltrate of lymphocytes at dermal-epidermal junction hep C assoc |
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pruritic
purple polygonal papules sawtooth infiltrate of lymphocytes at dermal-epidermal junction hep C assoc |
lichen planus
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actinic keratosis
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premalignant lesions due to sun exposure
small, rough, erythematous, or brown cutaneous horn |
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actinic keratosis can predispose to
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squamous cell carcinoma
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cutaneous horn
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actinic keratosis
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acanthosis nigricans
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hyperplasia of stratum spinosum
assoc with hyperlipidemia and visceral malignancy |
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erythema nodosum
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inflammatory lesions of subcutaneous fat,
usually on anterior shins, associated with: coccido, histo, TB, leprosy, strep, sarcoid |
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inflammatory lesions of subcutaneous fat,
usually on anterior shins, associated with: coccido, histo, TB, leprosy, strep, sarcoid |
erythema nodosum
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pityriasis rosea
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"herald patch" followed days later by "christmas tree" distribution
multiple papular eruptions, resolves spontaneously |
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palisading nuclei
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bcc
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exposure to sun and arsenic
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scc
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scc locations
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hands and face
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ulcerative red lesion
keratin pearls |
scc
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associated with chronic draining sinuses
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scc
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rolled edges with central ulceration
pearly papules |
bcc
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s-100 tumor marker
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melanoma
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melanoma: risk of mets correlates with
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depth of tumor
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dark with irregular borders
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melanoma
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precursor to melanoma
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dysplastic nevus (atypical mole)
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