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7 Cards in this Set
- Front
- Back
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-dronate suffix |
DONATE box Bisphosphonates Two P coins = structure simiar to pyrophosphate Large T-rex appetite = attach to hydroxyapatite in bone Classmate(osteoclast) stuck in donate box = osteoclasts bind to biphosphonate inhibiting their adherence to bony surface Preventing class from entering = Decrease developement of osteoclast precursors Popping classmates balloon = induce osteoclast apoptosis Elevated icecream = treat acute hypercalcemia Disorganized bone display = treat paget disease Standing on Massive calcified rock = treats hypercalcemia caused by malignancy |
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Calcitonin |
Curator Grabbing classmate = directly inhibits osteoclasts Disorganized bone display = treat paget disease Ice cream pouring down flank = promotes Ca2+ excretion by kidney standing on Massive calcified rock = treats hypercalcemia caused by malignancy Fallen icecream = can cause hypocalcemia |
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-dronate suffix side effects |
Corroded neck = Can cause upper GI side effects avoided by taking water and standing upright Crumbling Jaw = Can cause osteonecrosis of the jaw Falling Icecream = Can cause hypocalcemia |
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Estrogen therapy |
Female Cavewoman and symbol = Can prevent postmenopausal osteoporosis but increases risk of breast cancer Female gaurding waiting class = Inhibits differentiation of osteoclast precursors |
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Raloxifene |
Relax sign held by woman selective estrogen receptor modulator (SERM) treatment and prevention of postmenopausal osteoporosis Relaxing the waiting class = estrogen agonist (inhibits osteoclast differentiation) and antagonist in breast and uterus (reduced risk of breast cancer) |
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Parathyroid Hormone |
P(T)hD Convices osteobuilder to give crank drill = stimulates osteoblasts to express RANKL Crank drill = nuclear factor kappaB ligand (RANKL) Active classmate with crank drill = RANKL binds to RANK on osteoclast, increasing activity |
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Denosumab |
Dino suit man grabbing drill away Antibody spikes = is a monoclonal antibody against RANKL |
