Sfos Test Ii 18 Microcirculation

Front 1

Define: part of the vascular system comprised of small arterioles, capillaries and small venules whose function is to regulate blood flow and nutrient exchange betewen blood and tissue.

Back 1

Microcirculation

Front 2

What is the primary function of microcirculation?

Back 2

Regulate blood flow and nutrient exchange between blood and tissue

Front 3

What are the three types of capillaries?

Back 3

Continuous, fenestrated, and discontinuous

Front 4

Name the type of capillary: characterized by endothelium in close contact and in some capillaries tight junctions bind endothelial cell together.

Back 4

Continuous capillaries

Front 5

How is transfer of nutrients across continuous capillaries accomplished?

Back 5

diffsuion or transport processes (endocytosis) through the cell

Front 6

The heart, skeletal muscle, skin and brain (blood-brain) have what type of capillaries?

Back 6

Continuous

Front 7

Name the type of capillary: characterized by gaps between endothelial cellswhich allo diffusion of substance including some large and charge molecule into the interstitium.

Back 7

Fenestrated

Front 8

The kidney and intestines have what type of capillaries?

Back 8

Fenestrated

Front 9

Name the type of capillary: characterized by large gaps between endothelial cells that allo free exchange of very large molecules and blood cells between the blood and tissue.

Back 9

Discontinuous

Front 10

The liver, spleen and bone marrow have what type of capillaries?

Back 10

Discontinuous

Front 11

What are the three major factors influencing diffusion through the capillary membrane?

Back 11

Diffusion thickness, surface area and diffusivity

Front 12

Define: an expression of how easily a substance moves through a capillary membrane.

Back 12

Diffusivity.

Front 13

True/False: the same rules of diffusion through a membrane are applied to the capillary membrane.

Back 13

True (through 2 bilipid layers)

Front 14

What are four factors which alter diffusivity?

Back 14

size, solubility(hydrophobic good, hydrophilic bad), charge (bad), hormones and pharmaceutical which change membrane permeability

Front 15

What are the four forces that determine fluid movement through the capillary membrane?

Back 15

Capillary physical (hydrostatic) pressure, interstitial fluid hydrostatic pressure, plasma colloidal pressure, interstitial fluid colloid osmotic pressure.

Front 16

Define: physical force tending to push fluid out of a capillary

Back 16

Capillary physical (hydrostatic) pressure

Front 17

Define: the physical pressure outside the capillary tending to push fluid back into a capillary

Back 17

Intersitial fluid hydrostatic pressure

Front 18

Define: Chemical force that can be expressed as a pressure which tends to push fluid back into the capillary.

Back 18

Plasma colloid osmotic pressure

Front 19

Define: Chemical force which tends to push fluid out of the capillary

Back 19

Interstitial colloid osmotic pressure

Front 20

What three things work together to push fluid into the interstitial fluid?

Back 20

mean capillary pressure (17.3 mmHg), interstitial fluid pressure (-3 mmHg), and interstitial fluid colloid osmotic pressure (8 mmHg).

Front 21

What one pressure works to draw fluid out of the interstitial fluid?

Back 21

Capillary colloid osmotic pressure (28 mmHg)

Front 22

What is the net force of fluid pushed out of the capillary into the interstitial fluid?

Back 22

0.3 mmHg

Front 23

At what point in the capillary is the outward pressure favoring fluid fluid from capillaries?

Back 23

Arterial end

Front 24

At what point in the capillary is the inward pressure favoring fluid resorption from the capillary bed?

Back 24

Venous end

Front 25

What are two major structures in lymphatic anatomy?

Back 25

Lymphatic capillaries, and collecting lymphatics

Front 26

Define: thin walled dead-end lymphatic vessels.

Back 26

Lymphatic capillaries

Front 27

Define: larger bor thin-walled vessels with small amounts of smooth muscle.

Back 27

Collecting lymphatics

Front 28

What allows large molevules and cells to enter the lymphatic capillaries?

Back 28

Gaps or pores in the lymphatic capillaries

Front 29

What permits the one way flow of lymph through the lymphatic system?

Back 29

Vales made of endothelium flaps

Front 30

List the four functions of the lymphatic system (three removes and a minimize)

Back 30

1. Remove unabsorbed interstitial fluid 2. Remove interstitial protein 3. Remove cellular debris 4. Miminize interstitial pressure to prevent edema

Front 31

Describe intrinsic pumping of lymph.

Back 31

When the vessel becomes distended, the smooth muscle of lymph vessels contract and squeeze fluid across a valve which prohibits backflow.

Front 32

List the four factors contributing to edema.

Back 32

1. Increased capillary permeability 2. decrease in plasma colloid osmotic pressure 3. Elevated capillary pressure 4. Lymphatic obstruction