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5 Cards in this Set

  • Front
  • Back

FA/FI curve points

Reaches 0.4 rapidly


plateaus between 10-15 minutes at 0.8




Rate of rise:


N20>Des>Sevo>iso>En>Halo

FA/FAO

At 0.2 by about 5 mins


At 0.1 by about 10 minutes


just above 0.01 at 120mins




Rate of decrement


N20>Des>Sevo>iso>En>Halo

Context sensitive decrement times

50% and 80% decrement times remain the same with different durations of anaesthetics (3 and 5 mins)


90% decrement time - increases with increasing duration of anaesthetic (equal with desflurane up to 90min duration of anaesthetic then begins to accumulate - plateaus at 50min CSDT at 350mins)

Metabolism

3%


Liver -oxidation


CYP450 2E1

Toxic Metabolites

Inorganic and organic fluroides


Non-Trifluroacetic acid acetic compounds


Compound A (reaction with soda-lime)