Set H

Front 1

MOST TISSUES & ORGANS OF THE BODY ARE FREE OF

Back 1

MICROORGANISMS

Front 2

Advantage of normal flora

Back 2

Microbial antagonism

Front 3

Potential spread into sterile parts of body

Back 3

Disadvantage of normal flora


*Intestine may perforate, skin broken, extraction of tooth, perianal skin flora enters urinary tract*

Front 4

Sequence of Infection at the Cellular Level
, Begins with Attachment then

Back 4

1.Colonization–growth on tissue surface
2.Invasion of Tissues–molecular enhancement factors

Front 5

*Virulence/Molecular Enhancement Factors*


skin as the portal of entry. An enzyme that destroys its substrate of hyaluronic acid (holds cells together)

Back 5

1.Hyaluronidase:

Front 6

*Virulence/Molecular Enhancement Factors*


accelerates blood coagulation

Back 6

2.Coagulase:

Front 7

*Virulence/Molecular Enhancement Factors*


destroys neutrophils & macrophages and white blood cells

Back 7

3.Leukocidins:

Front 8

*Virulence/Molecular Enhancement Factors* 1.Hyaluronidase: skin as the portal of entry. An enzyme that destroys its substrate of hyaluronic acid (holds cells together)
2.Coagulase: accelerates blood coagulation 3.Streptokinase: dissolves clots after reaching certain density and goes into blood
4.Leukocidins: destroys neutrophils & macrophages and white blood cells

Back 8

ALL TOGETHER ILLUSTRATE QUORUM SENSING

Front 9

A substance that is poisonous to other organisms

Back 9

Toxin

Front 10

Altered toxin used to produce antibiotics

Back 10

Toxoid

Front 11

Soluble substances secreted into host tissues

Back 11

Exotoxins

Front 12

Part of the cell membrane (G–) released during cell division or lysis

Back 12

Endotoxins

Front 13

Enzyme exotoxins that lyse red blood cells

Back 13

Hemolysins