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8 Cards in this Set
- Front
- Back
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What is Itraconazole used for?
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DOC: blastomycosis, histoplasmosis, sporotrichosis, black molds
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What is the MOA of Griseofulvin?
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interacts with microtubules to disrupt mitotic spindles, thereby inhibiting mitosis
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What is Butenafine used for?
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cream used as DOC for all types tinea, except capitis
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Which species of malaria is resistant to chloraquine?
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Plasmodium falciparum
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What is the MOA of Atovaquone?
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mitochondrial electron transport chain inhibitor
teratogenic! |
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In what 4 ways does Chloroquine kill Malaria?
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1. transforms heme into a toxin for, thereby poisoning it
2. forms complexes that lyse the Plasmodium and RBCS 3. alkalizes the Plasmodia food vacuole.....starving it 4. inhibits plasmodia DNA synthesis |
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What is the DOC for Pneumocystis?
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TMP-SMZ
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What is the MOA for Albendazole/Mebendazole?
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bind to tubulin in cells of roundworms, preventing microtubule formation
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