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26 Cards in this Set
- Front
- Back
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What are the charachteristics of Seronegative Spondyloarthropathy
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affects axial skeleton, inflammatory, RF negative, Genetic Predisposition, Enthesopathic, Mucocutaneous Features
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name the common spondyloarthropathies
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Ankylosing spondylitis, Psoriatic Arthritis, Reactive Arthritis, Enteropathic Arthritis (crohns disease, ulcerative colitis), Juvenile Ankylosing Spondylitis
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What gene is often associated with spondyloarthropathies but is not necessary or sufficient to cause them
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HLA-B 27
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What are the typical nonvertebral symptoms of spondyloarthropathies
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Asymmetric Peripheral Arthritis, Arthritis of the toe IP joints, sausage digits, achilles tenosynovitis, plantar fasciitis, costochondritis, Iritis, Mucocutaneous Lesions
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What are the major charachteristics of ankylosing spondylitis
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inflammatory, insidious onset involving vertebra and SI intitially then pepheral joints, you will also have cardiac features 5-10% of the time and Iritis 10-20%. Male>F 4:1 with an age of onset of 15-40
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Who suffers from ankylosing spondylitis more
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4:1 M>F
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When does ankylosing spondylitis usually start
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ages 15-40
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What is the schobers test
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where you have patient bend when they flex you should go from lordosis to kyphosis. A Person with ankylosing spondylosis will not have any movement in their back as they bend all the movement will come from the hip
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What lab findings will you find in ankylosing spondylosis
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ESR increased 85% of time, RF usually negative, Mild anemai, HLA B27 positive 90%
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What x-ray finding is indicative of ankylosing spondylitis
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Bamboo Spine
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What eye finding are common in ankylosing spondylitis
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inflammation of eye uveitis and iritis when it goes all the way to the limbus
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What is the treatment for ankylosing Spondyltiis
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physical and occupation therapy to maintain posture, exercise (key), stop smoking, NSAIDS, Sulfalsalazine and MTX, Anti-TNF agents
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What are the essentials of dx Ankylosing Spondylitis
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chronic LBP in young adults gen worse in morning, progressive limitation of back motion or chest expansion, transient or permanent arthritis, inflammatory eye disease, elevated ESR, neg RF, HLA-B27, SI ( Sacroiliac Joint) abnormalitis on x-ray
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What are the classic characteristics of psoriatic arthritis
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Nail pitting/onycholysis, inflamm arth DIPs, Asym Arthritis, Sausage digits, no Rheum Nodules, RF -, erosive arthritis w/o osteopenia, Sacroilitis, syndesmophytes, paravert ossification, enthesopathy
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What are the patterns of arthritis in psoriatic arthritis
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DIP arthritis with nail changes, Asymmetirc oligoarthritis, symmetric polyarthritis, asymmetric spondylitsi is possible,
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What can be used to manage psoriatic arthritis
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Topical agents, PUVA, NSAIDs, Methotrexate, leflunomide, sulfasalazine, anti-tnf agents, surgery
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What are the essential to dx psoriatic arthritis
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80% of time psoriasis before the arthritis, asymmetric sausage appearance of fingers and toes, RF usually neg, SI involvement common with ankylosis, x-ray showing osteolysis, pencil in cup deformity, bony ankylosis, sacroiliitis, syndesmophytes
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What is reactive arthritis
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a seronegative asymmentric arthritis following urethritis or cervicitis or infectious diarrhea.
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What conditions are often associated with reactive arthritis
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enthesopathy (ligament or muscle abnromalities at where they attach to bone), Inflammatory eye disease, balanitis, Oral ulcers, or keratodermia and sacroiliitis
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What venereal disease can lead to reactive arthritis
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chlamydia trichomatis
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What enteric diseases can lead to reactive arthritis
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shigella flexneri, salmonella, yersinia enterocolitica, yersinia pseudotuberculcosis, campylobacter jejuni
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What condition can intravesicular bacille calmette-guerin lead to
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reactive arthritis
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What arthritis sometimes presents with keratodermia blenorrhagica
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Reactive arthritis
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What would a clacaneal spur be termed using medico lingo
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enthesopathy
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What is your typical mangement of reactive arthritis include
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antibiotics, NSAIDs, opthalmic RX, steroids, remittive agents MTX, SSZ, cytotoxic drugs and biologic agents
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What are the essential of dx of reactive arthritis
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50-89% HLA B-27 +, oligoarthritis, conjunctivitis, urethritis and mouth ulcers are most common, usually follows hx of dysentery or sexually transmitted infection
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