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46 Cards in this Set
- Front
- Back
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Does injection of protective Ab cause active or passive immunity?
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Passive
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Does injecting attenuated or killed Ag stimulate active or passive immunity?
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Active
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Does viral infection stimulate active/passive immunity?
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Active
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Does bacterial infection stimulate active or passive immunity?
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Active
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Does injection of protective Ab cause active or passive immunity?
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Passive
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Does Ab passage from Mom-fetus stimulate active or passive immunity?
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Passive
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Does injecting attenuated or killed Ag stimulate active or passive immunity?
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Active
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What is the nim mw for a substance to be an antigen?
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10,000 daltons
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Does viral infection stimulate active/passive immunity?
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Active
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Does bacterial infection stimulate active or passive immunity?
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Active
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What is an adjuvant?
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Something that enhances ANTIGENICITY - slows Ag release or allows MORE time for Ag interaction w/ the immune system.
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Does Ab passage from Mom-fetus stimulate active or passive immunity?
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Passive
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Humoral Immunity components:
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B cells
Antibody |
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What is the nim mw for a substance to be an antigen?
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10,000 daltons
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Cellular Immunity components:
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T cells
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What is an adjuvant?
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Something that enhances ANTIGENICITY - slows Ag release or allows MORE time for Ag interaction w/ the immune system.
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Identical action exhibited by Humoral and Cellular Immunity:
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Proliferation and Memory
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Humoral Immunity components:
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B cells
Antibody |
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Which cell has Erythrocyte receptor? What is the receptor's name?
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T cells - CD2 - E-rosettor
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Cellular Immunity components:
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T cells
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In lymph nodes, where do:
-T cells reside? -B cells reside? |
T: paracortex
B: germinal center |
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Identical action exhibited by Humoral and Cellular Immunity:
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Proliferation and Memory
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Which cell has Erythrocyte receptor? What is the receptor's name?
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T cells - CD2 - E-rosettor
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T cells mature where?
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Thymus
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In lymph nodes, where do:
-T cells reside? -B cells reside? |
T: paracortex
B: germinal center |
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T cells mature where?
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Thymus
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B cells mature where?
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Bone marrow
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B cells mature where?
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Bone marrow
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What is necessary for Antigen presentation to T cells by macrophages/monocytes?
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MHC II
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What is necessary for Antigen presentation to T cells by macrophages/monocytes?
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MHC II
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All immunoglobulins have what basic structure?
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2 Heavy chains
2 Light chains -Bound by disulfide bonds. |
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Which Ig binds MAST cells, via what?
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IgE - via Fc portion.
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IgG subclasses vary based on:
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Number of disulfide bonds.
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Which Ig's have J chains?
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IgM and IgA
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How many units are in:
-IgG -IgM -IgA |
IgG = 1 unit
IgM = 5 units IgA = 2 or 3 units |
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Which Ig's AGGLUTINATE?
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IgG - Incompletely
IgM - Completely |
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What is ALLOTYPE?
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Ig Constant region differences between persons of the same species.
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What is Isotype?
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Heavy chains differences among people.
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What is Idiotype?
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Differences in the VARIABLE regions of antibodies between people.
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Ig present in human serum in highest concentration?
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IgG
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Which Igs fix complement?
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IgM and IgG
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Which Igs cross placenta?
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IgG
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Give 3 characteristics of PRIMARY immune response:
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1. Occurs w/ 1st Ag contact
2. IgM, transient, evidence of ACUTE infection. 3. Slow comp w/ hypersens. or secondary immune response. |
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Give 2 characteristics of SECONDARY immune response:
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1. Requires previous Ag contact.
2. IgG, Fast, Long lasting |
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What is Affinity?
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Strength of single epitope binding/fit
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What is avidity?
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Strength of a multivalent Ag-Ab bond
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