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46 Cards in this Set

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Does injection of protective Ab cause active or passive immunity?
Passive
Does injecting attenuated or killed Ag stimulate active or passive immunity?
Active
Does viral infection stimulate active/passive immunity?
Active
Does bacterial infection stimulate active or passive immunity?
Active
Does injection of protective Ab cause active or passive immunity?
Passive
Does Ab passage from Mom-fetus stimulate active or passive immunity?
Passive
Does injecting attenuated or killed Ag stimulate active or passive immunity?
Active
What is the nim mw for a substance to be an antigen?
10,000 daltons
Does viral infection stimulate active/passive immunity?
Active
Does bacterial infection stimulate active or passive immunity?
Active
What is an adjuvant?
Something that enhances ANTIGENICITY - slows Ag release or allows MORE time for Ag interaction w/ the immune system.
Does Ab passage from Mom-fetus stimulate active or passive immunity?
Passive
Humoral Immunity components:
B cells
Antibody
What is the nim mw for a substance to be an antigen?
10,000 daltons
Cellular Immunity components:
T cells
What is an adjuvant?
Something that enhances ANTIGENICITY - slows Ag release or allows MORE time for Ag interaction w/ the immune system.
Identical action exhibited by Humoral and Cellular Immunity:
Proliferation and Memory
Humoral Immunity components:
B cells
Antibody
Which cell has Erythrocyte receptor? What is the receptor's name?
T cells - CD2 - E-rosettor
Cellular Immunity components:
T cells
In lymph nodes, where do:
-T cells reside?
-B cells reside?
T: paracortex

B: germinal center
Identical action exhibited by Humoral and Cellular Immunity:
Proliferation and Memory
Which cell has Erythrocyte receptor? What is the receptor's name?
T cells - CD2 - E-rosettor
T cells mature where?
Thymus
In lymph nodes, where do:
-T cells reside?
-B cells reside?
T: paracortex

B: germinal center
T cells mature where?
Thymus
B cells mature where?
Bone marrow
B cells mature where?
Bone marrow
What is necessary for Antigen presentation to T cells by macrophages/monocytes?
MHC II
What is necessary for Antigen presentation to T cells by macrophages/monocytes?
MHC II
All immunoglobulins have what basic structure?
2 Heavy chains
2 Light chains
-Bound by disulfide bonds.
Which Ig binds MAST cells, via what?
IgE - via Fc portion.
IgG subclasses vary based on:
Number of disulfide bonds.
Which Ig's have J chains?
IgM and IgA
How many units are in:
-IgG
-IgM
-IgA
IgG = 1 unit
IgM = 5 units
IgA = 2 or 3 units
Which Ig's AGGLUTINATE?
IgG - Incompletely

IgM - Completely
What is ALLOTYPE?
Ig Constant region differences between persons of the same species.
What is Isotype?
Heavy chains differences among people.
What is Idiotype?
Differences in the VARIABLE regions of antibodies between people.
Ig present in human serum in highest concentration?
IgG
Which Igs fix complement?
IgM and IgG
Which Igs cross placenta?
IgG
Give 3 characteristics of PRIMARY immune response:
1. Occurs w/ 1st Ag contact
2. IgM, transient, evidence of ACUTE infection.
3. Slow comp w/ hypersens. or secondary immune response.
Give 2 characteristics of SECONDARY immune response:
1. Requires previous Ag contact.
2. IgG, Fast, Long lasting
What is Affinity?
Strength of single epitope binding/fit
What is avidity?
Strength of a multivalent Ag-Ab bond