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28 Cards in this Set
- Front
- Back
The respiratory tract is divided into two main parts
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Upper and lower
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The upper respiratory tract, consists of
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the nose, nasal cavity and the pharynx
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The lower respiratory tract consists of
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the larynx, trachea, bronchi and the lungs
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The lungs are separated by the
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mediastinum
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The terminal parts of the bronchi are the
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alveol
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Histology least likely to recur after resection; frequently a central or bronchial lesion
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Squamous or epidermoid (807_3)
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Histology usually slow-growing, but can metastasize widely; usually a peripheral lesion
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Adenocarcinoma (814_3)
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Histology that is very specific subtype of adenocarcinoma with a distinct characteristic presentation and behavior. Bronchioloalveolar adenocarcinomas arise in the alveolar sacs in the lungs.
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Bronchioloalveolar (82503)
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Histology that is also called giant cell or clear cell Other subtypes of adenocarcinoma are acinar, papillary, and mucinous.
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Large cell carcinoma (80123)
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Histology that has a specific histologic variant containing both epithelial (squamous) and glandular (adeno-) cells.
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Adenosquamous carcinoma (85603)
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Histology that arise from neuroectoderm (which generates supporting structures of lung). Melanomas, sarcomas and lymphomas may also arise in the lung.
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Carcinoids (824_3)
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Histology linked to asbestos exposure; usually involves the pleura, not the lung.
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Mesothelioma (905_3)
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Histology that is a general term used sloppily to separate small cell from the "non-small cell" types (such as adenocarcinoma, squamous cell carcinoma, large cell, etc.) of carcinomas.
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Non-small cell carcinoma (80463)
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A tumor of the apex of lung which invades brachial plexus nerves causing pain in the arm.
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Pancoast tumor
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A less invasive tumor of the apex of the lung.
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Superior sulcus tumor
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It is a description of where the tumor arose: broncho- (bronchus) and -genic (arising in). More information should be obtained before the morphology is coded.
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Bronchogenic carcinoma (not a specific cell type)
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Common metastatic sites of lymphatic spread:
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Cervical lymph nodes, contralateral lung and contralateral mediastinum
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Common metastatic sites of hematogenous spread:
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Brain, bone, liver, adrenal glands, kidney, contralateral lung.
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glyco-protein which is present in extracts of carcinoma cells
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CEA
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Elevated levels of this thyroid hormone occasionally occur with small cell lung cancer; increasing levels may indicate progression of disease
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Calcitonin
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An antigen marker for cancers of gynecologic sites, bladder, and lung; nonspecific to ovarian and cancer; elevated levels indicate presence of malignancy; also used to monitor bladder and lung cancer in males.
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TPA (Tissue Polypeptide Antigen)
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Patients with this type of cancer are potentially curable with surgery, but largely unresponsive to chemotherapy. Patients with distant metastases from this can be treated palliatively with radiation.
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Non-small cell lung cancers (squamous, adenocarcinoma and large cell carcinoma
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Patients with this type of cancer do respond to chemotherapy and radiation, but are usually too far advanced at diagnosis for a surgical cure
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small cell lung cancer
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Exploratory surgical procedure in which the chest is opened to inspect the heart, lungs, and mediastinal contents. Thoracotomy does not necessarily include removal of tissue.
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Exploratory Thoracotomy
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Surgery of distant site—for example, resection of solitary brain tumor
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Mediastinotomy (also called median sternotomy or paramediansternotomy)
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To palliate obstructing lesions
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Endobronchial Laser Surgery
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Chemotherapy Commonly Used for Treating Non-Small Cell Lung Cancer
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Cisplatin, doxorubicin and cytoxan (under clinical evaluation)
Pre-operative Cisplatin and vindesine with or without mitomycin-C (under clinical evaluation) Carboplatin-containing regimens |
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Chemotherapy Commonly used for Treating Small Cell Lung Cancer
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All patients should receive combination chemotherapy regardless of the extent of disease.
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