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28 Cards in this Set

  • Front
  • Back
The respiratory tract is divided into two main parts
Upper and lower
The upper respiratory tract, consists of
the nose, nasal cavity and the pharynx
The lower respiratory tract consists of
the larynx, trachea, bronchi and the lungs
The lungs are separated by the
mediastinum
The terminal parts of the bronchi are the
alveol
Histology least likely to recur after resection; frequently a central or bronchial lesion
Squamous or epidermoid (807_3)
Histology usually slow-growing, but can metastasize widely; usually a peripheral lesion
Adenocarcinoma (814_3)
Histology that is very specific subtype of adenocarcinoma with a distinct characteristic presentation and behavior. Bronchioloalveolar adenocarcinomas arise in the alveolar sacs in the lungs.
Bronchioloalveolar (82503)
Histology that is also called giant cell or clear cell Other subtypes of adenocarcinoma are acinar, papillary, and mucinous.
Large cell carcinoma (80123)
Histology that has a specific histologic variant containing both epithelial (squamous) and glandular (adeno-) cells.
Adenosquamous carcinoma (85603)
Histology that arise from neuroectoderm (which generates supporting structures of lung). Melanomas, sarcomas and lymphomas may also arise in the lung.
Carcinoids (824_3)
Histology linked to asbestos exposure; usually involves the pleura, not the lung.
Mesothelioma (905_3)
Histology that is a general term used sloppily to separate small cell from the "non-small cell" types (such as adenocarcinoma, squamous cell carcinoma, large cell, etc.) of carcinomas.
Non-small cell carcinoma (80463)
A tumor of the apex of lung which invades brachial plexus nerves causing pain in the arm.
Pancoast tumor
A less invasive tumor of the apex of the lung.
Superior sulcus tumor
It is a description of where the tumor arose: broncho- (bronchus) and -genic (arising in). More information should be obtained before the morphology is coded.
Bronchogenic carcinoma (not a specific cell type)
Common metastatic sites of lymphatic spread:
Cervical lymph nodes, contralateral lung and contralateral mediastinum
Common metastatic sites of hematogenous spread:
Brain, bone, liver, adrenal glands, kidney, contralateral lung.
glyco-protein which is present in extracts of carcinoma cells
CEA
Elevated levels of this thyroid hormone occasionally occur with small cell lung cancer; increasing levels may indicate progression of disease
Calcitonin
An antigen marker for cancers of gynecologic sites, bladder, and lung; nonspecific to ovarian and cancer; elevated levels indicate presence of malignancy; also used to monitor bladder and lung cancer in males.
TPA (Tissue Polypeptide Antigen)
Patients with this type of cancer are potentially curable with surgery, but largely unresponsive to chemotherapy. Patients with distant metastases from this can be treated palliatively with radiation.
Non-small cell lung cancers (squamous, adenocarcinoma and large cell carcinoma
Patients with this type of cancer do respond to chemotherapy and radiation, but are usually too far advanced at diagnosis for a surgical cure
small cell lung cancer
Exploratory surgical procedure in which the chest is opened to inspect the heart, lungs, and mediastinal contents. Thoracotomy does not necessarily include removal of tissue.
Exploratory Thoracotomy
Surgery of distant site—for example, resection of solitary brain tumor
Mediastinotomy (also called median sternotomy or paramediansternotomy)
To palliate obstructing lesions
Endobronchial Laser Surgery
Chemotherapy Commonly Used for Treating Non-Small Cell Lung Cancer
Cisplatin, doxorubicin and cytoxan (under clinical evaluation)
Pre-operative Cisplatin and vindesine with or without mitomycin-C (under clinical evaluation)
Carboplatin-containing regimens
Chemotherapy Commonly used for Treating Small Cell Lung Cancer
All patients should receive combination chemotherapy regardless of the extent of disease.