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15 Cards in this Set

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Sedatives
Reduce activity with little effect on motor or mental functions
Hypnotics
Used to facilitate the onset and maintenance of sleep
CNS Depressants Action
Stimulation of GABA A receptor results in influx of chloride which hyperpolarizes the cell.
Benzodiazepine effect on ion channel
Increase the frequency of channel opening even in the absence of GABA - can induce fatal effects
Barbiturates effect on ion channel
Increases the duration of channel opening
Benzodiazepine Clinical Usage
Seizures
Physiological Dependence to other sedatives
Situational Anxiety
Anxiety Disorders
Insomnia
Barbiturates Clinical Usage
Seizures
Intravenous Anesthetics
Euthanasia

CAN PRODUCE FATAL EFFECTS!!
Adverse Effects of Sedatives
Withdrawl
Tolerance (esp. benzos)
Side Effects: Respiratory Depression, Increased HR, Overdose, Abuse Potential
Alcoholics and Benzos
Increased potential for abuse if already abusing a sedative (ie. Alcohol)
Drug Interactions
Any CNS Depressants
-Exhibit additive/synergistic effect with benzo/barb
Busiprone(Buspar)
Relieves anxiety w/out causing sedation or euphoria
Phenobarbital
Long lasting barbiturate (anti-seizure)
Methohexital
Ultra short-acting barbiturate (anesthesia)
Triazolam
Short acting benzodiazepine (insomnia)
Diazepam
long acting benzodiazepine (anxiety, alcohol detox)