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28 Cards in this Set

  • Front
  • Back

What is a sedative

Anxiolytic agent that reduces anxiety and exerts a calming effect

What is a hypnotic agent

Produces drowsiness and encourages the onset and maintenance of sleep

What are the important groups of Sedative-Hypnotics

Bensodiazepines


Barbituates


The Newer drugs

Describe Insomnia

May be primary with no other symptoms


May be secondary


May be temp or episodic

What are the types of insomnia

Sleeponset insomnia: Difficulty falling asleep


Sleepmaintaining insomnia: difficulty staying asleep


Earlymorning awakening: Waking up too early.

What can cause insomnia

Pain conditions


GI distress


Hypertnesion


Heart Disease


Diabetes


Psych Illness

Nonpharmacological treatments for insomnia

Lifestyle changes


Cognitive behavioral therapy


Relaxation therapy


Sleep-restriciton therapy


Stimulus-control therapy

Pharacotherapy of Insomia

Antihistsamines - Benadryl, Sominex, Unisom


Supplements and herbs


Benzodiazepines


Non-Benzodiazephine


Sedating antidepressants

What is the therapeutic effects of prescription meds for insomnia?

Shorten time to fall asleep


Increase total sleep time


Decrease number of awakenings


Improve sleep quality

What are the newer hypnotic agents

Zolpidem (Ambien)


-Potential for addiction


-Dowsiness


Zaleplon (Sonata)


-Short-acting


Eszopiclone (Lunesta)


-Only one approved for chronic use


Ramelteon (Rozerem)


-melatonin receptor agonist



What are the types of sedating antidepressants

Tricyclic agents


Trazodone


Mirtazapine



Treatment Duration

Adverse effects of sedative hypnotics

CNS Depression


Dizziness


Hypotension


Nausea


Cognitive impairment


-memory, concentration


Behavior changes


-Aggression, sleep walking

Addiction and abuse of Insomnia drugs

Benzodiazepine - most common


Antihistimines


Sedating antidepressants


Herbal Products

Tolerance and insomnia

Use of sedative-hypnotics for more than 1-2 weeks leads to some tolarnce




Abrupt withdrawal leads to more serious withdrawal signs



What is anxiety

Natural evolutionary response to stressful stimuli




Uncomfortable feeling of vague fear or apprehension with characteristic physical sensations

Symptoms of Anxiety

Racing heart, trembling, shortness of breath, pacing, worry, fear, difficulty concentrating

How to differentiate Pathological anxiety

in response to acute stress


secondary to medical causes


symptom with other psych disorder



What can cause secondary axiety

Endocrine


Neurological


Cardiovascular


Resp


GI

What Psych disorders may have anxiety as a symptom?

Bipolar


Major depression


Schizophrenia


Adjustment disorder

What medications are used for anxiety

Sed-Hypnotics


Anti-anxiety agents

What are the therapeutic effects of Benzodiazepines

Anxiolytic

Sed-Hypnotic


Muscle Relaxant


Anticonvulsant




Major uses for Benzo

Anxiety


Insomnia


Alcohol withdrawal


muscle spasticity


pre-surgical sedation

Mechanism of Benzodiazepine

What are the most common adverse effects of Benzo

Drowsiness


Ataxia


Slurred speech


Blurred Vision


Psych-motor impairment


Paradoxical reactions


Respiratory depression

Describe Tolerance to Benzo

Usually develops in about one week




Tolerance to the Anxiolytic, muscle relaxant and aniconvulsant effects not as likely tooccur

Describe Benzo Withdrawal

More common with shorter acting


Most common taking large doses for extended time.


Typically occurs after 3 mo of use


May begin within 24 hourss



Benzo implications for PTs

Inc risk for falls


within 2-4 hours after taking the drug patient will be calm, relaxed, drowsy, less able to focus