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24 Cards in this Set

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Diagnostic Criteria (DSM-IV) for Schizophrenia/Psychotic Disorder
2 or more of the following;
-Delusions
-Hallucinations
-Disorganized speech / incoherence
-Disorganized / catatonic behavior
-Negative symptoms
Social / occupational dysfunction*
Duration > 6 months
PDD hall/del > 1 month
Other mental d/o excluded
Substance / medical conditions excluded
Positive symptoms
del / hall / disorg speech / behavior

what schizophrenics have that normals don't
Negative symptoms
flat affect / anergia / withdrawal / anhedonia

What normals have that schizophrenics don't
most common type of sensory schizophrenic hallucination
auditory
***HISTORICAL
Bleuler’s 4 A’s of SZFN
Autism
Ambivalence
Affect (flattened)
A-volition
HISTORICAL
Kraepelin
distinguishing bipolar from early SCN(dementia praecox)
Dementia is:
remitting,
Non-cognitive impairment
Late onset (4th decade)
Good vocational / social outcome
HISTORICAL
Kraepelin
distinguishing bipolar from early SCN(dementia praecox)

Dementia praecox:
Early onset (2nd 3rd decade)
Cognitive impairment, permanent
Poor out-come
Bleuler suggested Schizophrenia more appropirate name
splitting of thought and affect prominent
***Kurt Schneider
First rank symptoms (pathognomonic)
Thought diffusion
Thought insertion
Voices arguing / commenting

No longer considered specific to SCP
SCN Sub-types
Paranoid – highest fxning
Undifferentiated – most common
Disorganized
Residual
catatonic
SCN percent of pop.
1%
mean onset for males & females
males 25/females 30
SES
lower
parents w/ SCN
10%
MZ twin studies
46%
Schizo-affective d/o
major depression or manic/depression signs and symptoms with superimposed SCN signs and symptoms

delusions and hallucinations for more than 2 weeks

mood disorder is prevolent
Delusional d/o
Non-bizarre delusions
Functioning spared
Types
-Erotomanic
-Grandiose
-Jealous
-Persecutory
-Somatic
-mixed
Brief Psychotic d/o
Same as SCP but < 1 month duration
Schizophreniform
Same as SCP but duration less (1 – 6 months)
Functioning preserved
Absence of blunted / flat affect
Good premorbid social and occupational funct.
Side Effects: Clozaril (Clozapine)
WBC, Sz, Hypr Sal
Zyprexa (Olanzapine)
sedation / DM/wt gain
Risperdal (Risperdone)
inc prolac / galactorrhea
Seroquel (Quetiapine)
cataract
Clozapine is excellent drug because
little or no EPS side effects