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24 Cards in this Set
- Front
- Back
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Diagnostic Criteria (DSM-IV) for Schizophrenia/Psychotic Disorder
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2 or more of the following;
-Delusions -Hallucinations -Disorganized speech / incoherence -Disorganized / catatonic behavior -Negative symptoms Social / occupational dysfunction* Duration > 6 months PDD hall/del > 1 month Other mental d/o excluded Substance / medical conditions excluded |
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Positive symptoms
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del / hall / disorg speech / behavior
what schizophrenics have that normals don't |
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Negative symptoms
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flat affect / anergia / withdrawal / anhedonia
What normals have that schizophrenics don't |
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most common type of sensory schizophrenic hallucination
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auditory
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***HISTORICAL
Bleuler’s 4 A’s of SZFN |
Autism
Ambivalence Affect (flattened) A-volition |
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HISTORICAL
Kraepelin distinguishing bipolar from early SCN(dementia praecox) Dementia is: |
remitting,
Non-cognitive impairment Late onset (4th decade) Good vocational / social outcome |
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HISTORICAL
Kraepelin distinguishing bipolar from early SCN(dementia praecox) Dementia praecox: |
Early onset (2nd 3rd decade)
Cognitive impairment, permanent Poor out-come |
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Bleuler suggested Schizophrenia more appropirate name
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splitting of thought and affect prominent
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***Kurt Schneider
First rank symptoms (pathognomonic) |
Thought diffusion
Thought insertion Voices arguing / commenting No longer considered specific to SCP |
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SCN Sub-types
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Paranoid – highest fxning
Undifferentiated – most common Disorganized Residual catatonic |
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SCN percent of pop.
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1%
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mean onset for males & females
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males 25/females 30
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SES
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lower
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parents w/ SCN
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10%
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MZ twin studies
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46%
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Schizo-affective d/o
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major depression or manic/depression signs and symptoms with superimposed SCN signs and symptoms
delusions and hallucinations for more than 2 weeks mood disorder is prevolent |
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Delusional d/o
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Non-bizarre delusions
Functioning spared Types -Erotomanic -Grandiose -Jealous -Persecutory -Somatic -mixed |
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Brief Psychotic d/o
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Same as SCP but < 1 month duration
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Schizophreniform
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Same as SCP but duration less (1 – 6 months)
Functioning preserved Absence of blunted / flat affect Good premorbid social and occupational funct. |
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Side Effects: Clozaril (Clozapine)
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WBC, Sz, Hypr Sal
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Zyprexa (Olanzapine)
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sedation / DM/wt gain
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Risperdal (Risperdone)
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inc prolac / galactorrhea
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Seroquel (Quetiapine)
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cataract
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Clozapine is excellent drug because
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little or no EPS side effects
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