Study your flashcards anywhere!

Download the official Cram app for free >

  • Shuffle
    Toggle On
    Toggle Off
  • Alphabetize
    Toggle On
    Toggle Off
  • Front First
    Toggle On
    Toggle Off
  • Both Sides
    Toggle On
    Toggle Off
  • Read
    Toggle On
    Toggle Off
Reading...
Front

How to study your flashcards.

Right/Left arrow keys: Navigate between flashcards.right arrow keyleft arrow key

Up/Down arrow keys: Flip the card between the front and back.down keyup key

H key: Show hint (3rd side).h key

A key: Read text to speech.a key

image

Play button

image

Play button

image

Progress

1/68

Click to flip

68 Cards in this Set

  • Front
  • Back
schizoprenia
dz that produces multiple s/s involving thought, behavior, emotion and perception
dopamine hypothesis
an excess of dopamine to be the cause of schizoprenia
glutamate
dominant neurotransmitter in the cerebral cortex and one of its functions is to modulate dopamine activity
characteristic symptoms
delusions
hallucinations
disorganized speech
catatonic behavior
negative symptoms
types of schizo
catatonic
disorganized
paranoid
residual
undifferentiated
most prominent symptoms of schizo
hallucinations
delusions
catatonic
marked pyschomotor disturbances
disorganized
marked incoherence with inappropriate responses

hypochondriacal behavior may be present
paranoid
delusions of grandeur or persecution
residual
vague associations
illogical thinking
withdrawal affect
living skills impaired
undifferentiated schizo
may incorporate prominent delusions, hallucinations, incoherence or grossly disorganized behavior
2 major therapeutic approaches for trmt
psychotherapy
pharmacotherapy
positive symptoms of schizo
hallucinations
delusions
thought disorders
disorganized speech
bizarre behavior
insomnia
combativeness
negative symptoms of schizo
affective flatterning
alogia
apathy
amotivation
anhedonia
asocial behavior
inattentiveness
traditional antipsychotic agts moa
exert their eff by blocking dopamine activity
high potentcy agents
more extrapyramidal symptoms
low potency agents
more sedation
anticholinergic
cardiovascular se
efficacy
effective in treating + sx
atypical agts
address the - sx
traditional agts adv eff
not well tolerated
properties of traditional antipsychotics
phenothiazines
thioxanthenes
butyrophenones
dihydroindolone
dibenzoxazepine
phenothiazines
chlorpromazine
trifluoperazine
thioridazine
mesoridazine
perphenazine
fluphenazine
thixanthene
thiothixene
butyrophenone
haloperidol
dihydroindolone
molindone
dibenzoxazepine
loxapine
antiphyscotic side eff
anticholinergic se
sedation
rahs
photosensitivity
thermoregulation dysfxn
lowered sz threshold
orthostatic hypotension
ECH chgs
hyperprolactenemia
elevated liver transaminases
bld dyscrasia
wgt gain
sexual dysfxn
extrapyramidal sx
ocular opacities
neuroleptic malignant sx
anticholinergic side eff
blurred vision
constipation
dry mouth
urinary retention
pharmacotherapy for tardive dyskinesia
reserpine
benzodiazepines
baclofen
valproic deriv
vit e
acute dystonias
involve sudden muscle spasms
sudden muscle spasms
torticollis
retrocollis
oculogyric crisis
trismus
torticollis
neck twisted to side
retrocollis
neck/head pulled back
trismus
clenched jaw
oculogyric crisis
fixed upward gaze
trmt acute dystonia
anticholinergic agents

diphenhydramine
benztropine
akathisia
motor restlessness
inner tension
agitation
akathisia trmt
b blker
bzd
anticholinergic agts
pseudoparkinsonism
drug induced by dopamine blkade agts

shuffling gait
masked faces
cogwheel rigidity
pill rolling tremor
dopamine blkade agts
antipsychotics
tardive dyskinesia
latent extrapyrimidal eff generally not occurring for mos or yrs

characterized by abnormal movements that can occur in any part of the body incl face, tongue, shoulders, hips, extremitites, fingers and toes
2 general types of movements
dystonic
choreoathetoid
dystonic
fixed
held muscle
choreoathetoid
writhing
rhythmic
td etiology
movements thought to occur fr porlonged dopamine blkade -> upregulation of dopamine rec and inc sensitivity to dop stimulation

generation of free radicals from lipid peroxidation 2ndary to inc neurotransmitter turnover
prevention
best measure against td prevention
measurement toolsof td
abnormal involuntary movement scale (aims)

dyskinesia indentification system condensed user scale (discus)
applied at baseline and every 3-6mos
NMS
neuroleptic malignant syndrome
def of dms
syndrome of extrapyrimidal eff, hyperthermia, altered consciousness and autonomic changes
autonomic changes
tachy
unstable bp
diaphoresis
incontinence
specific mgmt of nms
dc antipsychotic
provide supportive measures
dantrolene or bromocriptine
QTc prolongation
inc the risk for fatal vent arrhy (torsades de pointes)
list of atypical antipsychotics
clozapine
risperidone
olanzapine
quetiapine
ziprasidone
diff bet traditional and atypical agts blkage
traditional - blk D2 rec
atypical - blk sertonin rec
extrapyrimidal se- atypical
fewer than traditional
elevations of prolactin
not produced by atypical agts
hyperprolatinemia
traditional agts
rec affinity for atypical
5 ht rec
clozapine
refractory pts
eps/td free
reserved as last line therapy due to inc incidence of agranulocytosis and frequent lab monitoring- cbc
ziprasidone inj
only parenteral atypical agt
rapid tranquilization
reserved for acutely psychotic pts with agitation and aggression
adv eff histamine
sedation
adv eff serotonin - 5ht
wgt gain
adv eff dopamine
extrapyrimidal sx
hyperprolactenemia
adv eff muscarinic
anticholinergic eff
cognitive/memory inpairment
tachy
adv eff alpha 1
orthostatic hypotension
reflex tachy
long acting
fluphenazine
haldol
most common augmentative therapy
addition of a mood stabilizer to the antipsychotic regimen

typically - valproic acid, cbz or lithium, bzd