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35 Cards in this Set
- Front
- Back
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Low potency antipsych
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Chlorpromazine
Thioridazine |
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High potency antipsych
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Fluphenazine
Haloperidol |
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Dx criteria for Schizophrenia
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>6months of psychosis/distubed behavior and decline in functioning
2+ of: 1. Delusions 2. Hallucinations 3. Disorganized thought 4. Disorganized behavior 5. Negative symptoms |
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Negative symptoms in Schizophrenia
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Flat affect
Social withdrawal Lack of motivation Lack of speech or thought |
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Schizophrenia subtypes
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Dis Cat PUR
Disorganized Catatonic Paranoid Undifferentiated Residual |
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What other psych disorders are on the Schizophrenia spectrum?
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Schizotypal PD
Schizoaffective Disorder Schizophreniform Disorder (1-6 months) Brief psychotic disorder (<1 month) |
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Novel neuroleptics
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Clozapine
Risperidone Olanzapine Quetiapine Aripiprazole |
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Which neuroleptics are associated with an increased risk of metabolic syndrome and weight gain?
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Olanzapine
Quetiapine |
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Which antipsychs, 1st gen or 2nd gen, can cause Neuroleptic malignant syndrome?
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1st gen
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Which DA pathway is responsible for EPS?
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nigrostriatal
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Which receptors do 1st gen antipsychs block?
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D2
H1, alpha1, mACh |
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What are the side effects of 1st gen antipsychs?
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H1 (sedation, weight gain)
alpha1 (orthostatic HTN) mACh (dry mouth, blurred vision, constipation and urinary retention) decreased seizure threshold prolonged QT interval (increase VT risk) |
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Which receptors do novel neuroleptics block?
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D2 and 5HT2A simultaneously
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Which is more likely on risperidone: anti-mAChR sx or EPS?
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EPS
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What is the most effective neuroleptic?
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There is none, they're all equally effective
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negative symptoms and cognitive side effects of neuroleptics due to which DA pathway?
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Mesocortical
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Describe Schizoid PD
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Shy, lack of interest in anything
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What features of Schizophrenia are associated with improved prognosis?
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paranoid features, late onset with associated life problems
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Is Schizophrenia accompanied by dementia?
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No
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Cortical dementia is seen in what dz?
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Alzheimer's
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Subcortical dementia is seen in what dz?
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Huntington's
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Which type of dementia (cortical or subcortical) shows loss of immediate short term memory?
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Cortical
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Which type of dementia (cortical or subcortical) shows difficulty learning new things?
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Both
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Which type of dementia (cortical or subcortical) shows attention deficits?
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Subcortical
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Alzheimer's prevalence >65yo
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10%
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What treatments have been shown to improve or slow progression of Alzheimer's?
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Physostigmine, Vit. E, ginkgo biloba, ibuprofen
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What characterizes the demential associated with Parkingson's dz?
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difficulty learning new info.
slowed thinking reduced semantic fluency problem solving difficulties |
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What disorder may precede and significantly contribute to pseudodementia?
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Major depression
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Is Depression a common cause of dementia in the elderly?
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No!
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What disorder is associated with AIDS (nearly all AIDS patients get it)?
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Dementia
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Describe Neuroleptic Malignant Syndrome
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fever
leukocytosis rapid onset delirium |
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An anxiety disorder is present when anxiety is..
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– excessively more severe than normally associated with the stimulus
– present in the absence of a recognizable stimulus – uncontrollable or interfering or severely distressing |
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What medical conditions may cause anxiety?
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thyroid, cardiac and seizures
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what substances may induce anxiety?
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stimulants (caffeine), sedative withdrawal
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Which anxiety disorder does Buspirone treat?
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GAD
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