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6 Cards in this Set

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Describe the adenovirus
DNA; non-enveloped; double-stranded (DS) liner
febrile pharyngitis-sore throat; acute hemorrhagic cystitis
pneumonia
conjunctivitis-pink eye (watery)
Describe the epstein barr virus (EBV)
herpesvurus; DNA; enveloped; DS linear
causes mononucleosis; infects B cells
fever, hepatosplenomegaly, pharyngitis, lymphadenopathy (posterior cervical nodes); peak incidence 15-20 years old (peak kissing years)
reactive circulating cytotoxic T cells (atypical lymphocytes) react to EBV-infected cells
associated w/ development of Hodgkin's and Burkitt's lymphomas and nasopharyngeal carcinoma
positive Monospot test-heterophile Abs detected by agglutination of sheep RBCs
Describe the rhinovirus
picornavirus; RNA; non-enveloped; single-stranded (SS) + linear; icosahedral
cause of common cold; >100 serologic types
Acid labile (destroyed by stomach acid); doesn't infect GI tract
Describe the coronaviridae
RNA virus; enveloped; SS + linear; helical
common cold and SARS
Describe the paramyxovirus
RNA virus; enveloped; SS (-) linear; nonsegmented; helical
cause disease in children:
1. parainfluenza (croup)-seal like barking cough
2. mumps
3. measles (rubeola)
4. RSV-causes respiratory tract infections (bronchiolitis, pneumonia) in infants
contain surface F (fusion) protein which causes respiratory epithelial cells to fuse and form multinucleated cells
Describe the measles (rubeola) virus
paramyxovirus; RNA; enveloped; SS (-) linear; nonsegmented; helical
causes measles; Koplik spots (red spots w/ blu-white center on buccal mucosa) are diagnostic
possible sequalae-SSPE, encephalitis, giant cell pneumonia
rash presents lasts, spreads from head to toe, includes hands and feet
3 Cs of measles-cough, coryza, conjunctivitis (and Koplik spots)