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14 Cards in this Set
- Front
- Back
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What might you see on a diagnostic work up for fungal disease?
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mild anemia
inflammatory leukogram with a left shift on CBC increased immunoglobins, low albumin and slight hypercalcemia on chemistry may see uvuitis on eye exam |
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What are differential diagnoses for hypercalcemia?
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Neoplasia
Renal Disease Fungal Disease Osteolytic disease Hyperphosphotemia |
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What are fungal infections that affect lung and bone?
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histoplasmosis
blastomycosis coccidiomycosis |
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How can you confirm a fungal infection?
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cytology/histology
culture serology organism ID |
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What are advantages/disadvantages of antigen testing?
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-indicates that the org is present (A)
-False neg if org is difficult to detect (D) -Cross reactions (D) |
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What disadvantages of antibody testing?
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-negative in early infection (D)
-False positive - due to previous exposure -Vax can cause false positive |
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How do you confirm a positive antibody test?
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acute and convalescent antibodies
degree of antibody increase Type of Ab (IgM VS IgG) |
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What are common antifungal treatments?
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amphotericin B
Azoles ketoconazole Fluconazole itraconazole |
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What antifungals that are used for dermatophytes?
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Griseofulvin - P450 enzyme inducer
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What antifungals can be used for the CNS?
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Fluconazole
Amphotericin B Flucytosine |
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What fungal infections are caused by inhalation?
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blastomycosis (itraconazole)
histoplasmosis (itraconazole) cryptococcus (ketoconazole) Aspergilosis - intact cribiform plate (eniloconazole) Coccidiodomycosis (keto, itra, flu) |
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What fungal infections are caused by inoculation?
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Sporotrichosis (Azoles)
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What are reasons for using glucocorticoids in patients with fungal disease?
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use when there is life threatening inflammation in the lungs or brain
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What fungal disease is more common in cats?
Dogs? |
cryptococcus
Aspirgillosis |
